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112841por Lu, Roujian, Zhao, Xiang, Li, Juan, Niu, Peihua, Yang, Bo, Wu, Honglong, Wang, Wenling, Song, Hao, Huang, Baoying, Zhu, Na, Bi, Yuhai, Ma, Xuejun, Zhan, Faxian, Wang, Liang, Hu, Tao, Zhou, Hong, Hu, Zhenhong, Zhou, Weimin, Zhao, Li, Chen, Jing, Meng, Yao, Wang, Ji, Lin, Yang, Yuan, Jianying, Xie, Zhihao, Ma, Jinmin, Liu, William J, Wang, Dayan, Xu, Wenbo, Holmes, Edward C, Gao, George F, Wu, Guizhen, Chen, Weijun, Shi, Weifeng, Tan, Wenjie“…Notably, homology modelling revealed that 2019-nCoV had a similar receptor-binding domain structure to that of SARS-CoV, despite amino acid variation at some key residues. INTERPRETATION: 2019-nCoV is sufficiently divergent from SARS-CoV to be considered a new human-infecting betacoronavirus. …”
Publicado 2020
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112842por Geng, Yan, Guan, Renguo, Hong, Weifeng, Huang, Bowen, Liu, Peizhen, Guo, Xiaohua, Hu, Shixiong, Yu, Min, Hou, Baohua“…Moreover, we identified four m6A RNA methylation related genes expressed significantly differently among these seven subgroups, including collagen type VII alpha 1 chain (COL7A1), branched chain amino acid transaminase 1 (BCAT1), zinc finger protein 596 (ZNF596), and PLK1. …”
Publicado 2020
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112843por Holloway, Cassie L, Boyd, R Dean, Koehler, Dean, Gould, Stacie A, Li, Qingyun, Patience, John F“…Therefore, two experiments were conducted to determine if performance could be improved by feeding phytase at super-dosed levels, and whether this response would be different if energy and amino acid (AA) were limiting. Experiment 1 involved 440 weaned pigs (6.27 ± 0.01 kg) in a factorial arrangement of treatments comparing the main effects of diet (positive control [PC] balanced for all nutrients vs. a negative control [NC]: 10% lower standardized ileal digestible (SID) lysine with relative reduction of all other essential AA and 1% reduced fat) and phytase levels (0 vs. 2,500 FTU Quantum Blue 5G phytase/kg). …”
Publicado 2018
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112844por Carmichael, Remy N, Genther-Schroeder, Olivia N, Deters, Erin L, Jackson, Trey D, Messersmith, Elizabeth M, VanValin, Katherine R, Hansen, Stephanie L“…Steers were stagger started (four blocks of eight steers) and stratified by BW within growing diets to one of two Zn strategies (ZNTRT), no supplemental Zn (analyzed 36 mg Zn/kg dry matter [DM]; CON) or supranutritional Zn (CON + 60 mg Zn/kg DM as ZnSO(4) + 60 mg Zn/kg DM as Zn–amino acid complex; SUPZN). Dietary fiber strategies (FIBER) were formulated to target two fiber supplementation rates representing high fiber (HF; ~35% neutral detergent fiber [NDF]) or low fiber (LF; ~25% NDF). …”
Publicado 2019
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112845por Seraphim, Carlos Eduardo, Canton, Ana Pinheiro Machado, Montenegro, Luciana Ribeiro, Piovesan, Maiara Ribeiro, Bohlen, Tabata Mariz, Frazao, Renata, Macedo, Delanie Bulcão, de Faria, Aline Guimarães, Ramos, Carolina, Gagliardi, Priscila Carvalho, Abreu, Ana Paula, Leal, Andrea de Castro, Castro, Margaret De, Antonini, Sonir Roberto Rauber, Soriano-Guillén, Leandro, Escribano-Muñoz, Arancha, Collado, Raquel Corripio, Labarta, Jose Ignacio, Lourdes, Travieso-Suárez, Ortiz-Cabrera, Neimar Valentina, Argente, Jesús, Mendonca, Berenice Bilharinho, Kaiser, Ursula B, Brito, Vinicius Nahime, Latronico, Ana Claudia“…A frameshift mutation affecting codon 161 in the amino terminal region of the protein was the most frequent MKRN3 defect (46%), representing a hotspot region. …”
Publicado 2020
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112846por Thomas, Guillermo Javier, Peverini, Agustina, Smithuis, Fernando, Fabbro, Dolores, Tkatch, Julieta, Rosmino, Josefina, Aranda, Claudio, Guitelman, Mirtha, Oneto, Adriana“…For that reason we analyzed serum samples from 80 healthy pregnant women living in the Metropolitan Area of Buenos Aires (AMBA): 22 were in the 1(st) trimester (1T), 29 in the 2(nd) (2T) and 29 in the 3(rd) (3T). …”
Publicado 2020
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112847por Arguello, Mingxue“…Lung cancer is known to secrete PTHrp and PTHrp secreting hepatic cellular carcinoma (HCC) is exceedingly rare. …”
Publicado 2020
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112848por Garrahy, Aoife, Galloway, Iona, Hannon, Anne Marie, Dineen, Rose, Gan, K J, Javadpour, Mohsen, Tormey, William T, Twomey, Patrick J, McKenna, Malachi J, Kilbane, Mark, Sherlock, Mark, Crowley, Rachel K, Thompson, Chris J“…Serum markers of bone remodeling (total procollagen type 1 amino-terminal propeptide (P1NP), bone specific alkaline phosphatase (bone ALP), N-mid-osteocalcin (OCI) and C-terminal teleopeptides of type I collagen (CTX-1)) were assessed in a cohort of patients admitted with subarachnoid hemorrhage (SAH), who were prospectively studied over seven days. …”
Publicado 2020
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112849por Goodchild, Emily, Stoetaert, Jan, Drake, William, Linton, Kenneth, Brown, Morris Jonathan“…Methods Comparative bioinformatic analysis of the SLC35F1 amino acid sequence was carried out. Ex vivo 4uM adrenal sections, from 6 PA patients in the MATCH study, were stained on serial sections with anti-CYP11B2 (Gomez-Sanchez) or anti-SLC35F1 (Novus NBP1-86755). …”
Publicado 2020
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112850“…Of the two ChPUM proteins, ChPUM2 was most similar in amino acid sequence (27% identity and 45% homology) and predicted protein structure to Arabidopsis APUM23, while ChPUM3 was similar to APUM24 (35% identity and 54% homology). …”
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112851por Hussein, Maytham, Karas, John A., Schneider-Futschik, Elena K., Chen, Fan, Swarbrick, James, Paulin, Olivia K. A., Hoyer, Daniel, Baker, Mark, Zhu, Yan, Li, Jian, Velkov, Tony“…Concordant with its time-dependent antibacterial killing action, Leu(10)-teixobactin caused more perturbations in the levels of key intermediates in pathways of amino-sugar and nucleotide-sugar metabolism and their downstream peptidoglycan and teichoic acid biosynthesis at 3 and 6 h. …”
Publicado 2020
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112852“…A signal of positive selection was also detected in the receptor-binding motif (RBM) of the spike protein but most likely resulted from a recombination event that involved the BatCoV RaTG13 sequence. In line with previous data, we suggest that the common ancestor of SARS-CoV-2 and BatCoV RaTG13 encoded/encodes an RBM similar to that observed in SARS-CoV-2 itself and in some pangolin viruses. …”
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112853“…RESULTS: The serum levels of bone turnover markers (type I procollagen amino‐terminal peptide [P1NP], type I collagen carboxyl terminal peptide [β‐CTx], and osteocalcin [OC]) decreased, while the bone mineral density of the lumbar spine and bilateral femoral neck increased after treatment in the experiment group (P < 0.05, P < 0.01). …”
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112854“…FishTaco analysis identified Ruminococcus and Coprococcus as the taxa potentially contributing to the enriched KEGG pathways for biosynthesis of amino acids and to the metabolisms of pyruvate, glycerophospholipid, and nicotinate and nicotinamide in the rumen of HE-fed cows. …”
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112855“…Antioxidant activities were analyzed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay. …”
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112856por Suria, Andrea M., Tan, Karen C., Kerwin, Allison H., Gitzel, Lucas, Abini-Agbomson, Lydia, Bertenshaw, Jessica M., Sewell, Jaydeen, Nyholm, Spencer V., Balunas, Marcy J.“…JC28 had a 14-gene cluster with >95% amino acid identity to a known bromoalterochromide (BAC) cluster. …”
Publicado 2020
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112857“…Furthermore, there was an increased synthesis of heat shock proteins and unfolded proteins that could reduce the availability of circulating amino acids for milk protein synthesis. The findings of the current experiment may help to explore the impact of heat stress on immune function, milk production, and milk protein synthesis in cows. …”
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112858por Kabaka, Joy M., Wachira, Benson M., Mang’era, Clarence M., Rono, Martin K., Hassanali, Ahmed, Okoth, Sylvance O., Oduol, Vincent O., Macharia, Rosaline W., Murilla, Grace A., Mireji, Paul O.“…Most enriched biological processes in the head were associated with vision, muscle activity and neuropeptide regulations, amino acid/nucleotide metabolism and circulatory system processes. …”
Publicado 2020
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112859por Giunta, Diego Hernán, Marquez Fosser, Santiago, Boietti, Bruno Rafael, Ación, Laura, Pollan, Javier Alberto, Martínez, Bernardo, Luna, Daniel, Bonella, Maria Belen, Grande Ratti, María Florencia“…METHODS: This retrospective cohort included patients who had a First-H in Hospital Italiano de Buenos Aires between 2014–2015. Follow-up occurred from discharge until ED-visit, readmission, death, disaffiliation from health insurance, or 13 months. …”
Publicado 2020
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112860por Naranjo Nuñez, Luis F., Santander-Parra, Silvana H., Kyriakidis, Nicolaos C., Astolfi-Ferreira, Claudete S., Buim, Marcos R., De la Torre, David, Piantino Ferreira, Antonio J.“…The phylogenetic analyses of the sequences obtained herein classified CAstV as uniquely belonging to group B iv, showing a high similarity of nucleotides (NT) (75.7–80.6%) and amino acids (AA) (84.2–89.9%) with the members of group B and a low similarity of NT (46.7–47.9%) and AA (37.8–38.9%) with the virus belonging in group A. …”
Publicado 2020
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