“…However, genome-wide analysis showed that average nucleotide identity (ANI, 95.47%), DNA-DNA in silico hybridization (dDDH, 61.9%), average amino acid identity (AAI, 97.13%), TETRA (0.99%) and intergenic distance (0.04) values were below the established thresholds for differentiation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Generally, the swine 1A lineage viruses that seeded the 2009 H1 pandemic were antigenically most similar to the H1 pandemic vaccine strains, with the exception of viruses in the genetic clade 1A.1.1.3, which had a two-amino acid deletion mutation near the receptor-binding site, which dramatically reduced antibody recognition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we report a ceftazidime-avibactam-resistant and carbapenem-susceptible Klebsiella pneumoniae strain carrying a novel KPC variant, KPC-112, which differs from KPC-2 by 4-amino-acid deletions at Ambler positions 166L/167E and 242G/243T. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…KEGG enrichment showed that when the virus first invades (eats the leaf-discs), EcobNPV-QF4 mainly affects pathways such as ribosome (p-value = 2.47 × 10(−29)), and at 48 hpi EcobNPV-QF4, causes dramatic changes in the amino-acid-synthesis pathway and ribosome pathway (p-value = 6.94 × 10(−13)) in E. grisescens. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Metabolites mainly associated with nucleoside, carbohydrate, amino acid, bile acid, fatty acid, polyol, steroid and amine metabolism were identified in the faeces using untargeted GC/MS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…At 5 months of age, after the introduction of an amino acid-based formula (Neocate LCP Nutricia ®), an improvement of enteral feeding was observed, with no further and significantly decreased episodes of abdominal distension and vomiting respectively, and regular stool emission. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Levels of total procollagen type I amino-terminal propeptide (tPINP), osteocalcin (OC), serum calcium and phosphate were significantly lower (P < 0.001) while the level of parathormone (PTH) was significantly higher (P = 0.004) in COPD than in controls. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the present study, a combination of lysolecithin, synthetic emulsifiers and monoglycerides was able to significantly increase nutrient and amino acid digestibility in growing pigs, driving significant increases in growth, efficiency and the economics of production. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SIMPLE SUMMARY: Reliable differentiation between true tumor progression and treatment-related changes is a challenging situation in the management of glioma patients. Both amino-acid PET and perfusion MRI, as well as their combination, play a central role in this decision. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…PPAR signaling pathway, AMPK signaling pathway, insulin signaling pathway, carbon metabolism, pyruvate metabolism, fatty acid metabolism, regulation of lipolysis in adipocytes, biosynthesis of amino acids, citrate cycle (TCA cycle) and 2-Oxocarboxylic acid metabolism were the top 10 pathways involving in the upregulated DEGs, and graft-versus-host disease, allograft rejection, viral myocarditis, cell adhesion molecules, phagosome, type I diabetes mellitus, antigen processing and presentation, autoimmune thyroid disease, intestinal immune network for IgA production and rheumatoid arthritis were the top 10 pathways in downregulated DEGs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the open reading frame (ORF) S, mutations associated with vaccine escape and diagnostic failure were detected in 7.8% of the sequences (17/217) [AHB: 3.8% (3/79), CHB: 10.1% (14/138)]. ORF-P amino acid substitutions associated with antiviral resistance were detected in 3.2% of the samples (7/217) [AHB: 1.3% (1/79), CHB 4.3%, (6/138)]. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Seven existed single nucleotide polymorphism in GSV section can be translated into eleven various amino acid sequences. CONCLUSIONS: Generally, this study, indicating that orfH79 was always accompanied by the B-atp6, not only provide two original CMS sources for rice breeding, but also confirm the uniform structure of B-atp-orfH79, which contribute to revealing the origin of rice gametophytic CMS genes, and the reason about frequent recombination of mitochondrial DNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Results: The Raman spectra showed significant differences in the levels of uric acid (640 cm(−1)), urea, creatinine (1,608, 1,706 cm(−1)), proteins/amino acids (642, 828, 1,556, 1,585, 1,587, 1,596, 1,603, 1,615 cm(−1)), and ketone body (1,643 cm(−1)) (p < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In sum, the current important results of this thorough research work exposed the interesting repurposing potential of the three 2-amino-1,3,4-thiadiazole ligands, ChloViD2022, Taroxaz-26, and CoViTris2022, to effectively conflict with the vital biointeractions between the coronavirus's polymerase/exoribonuclease and the four essential RNA nucleotides, and, accordingly, arrest COVID-19 disease, persuading the relevant investigators to quickly begin the three agents' comprehensive preclinical and clinical anti-COVID-19 assessments.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Pulses are an important source of energy and protein, essential amino acids, dietary fibers, minerals, and vitamins, and play a significant role in addressing global nutritional security. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SIMPLE SUMMARY: Soybean meal is currently one of the most widely used ingredients in aquafeed due to its consistent supply, reasonable price, and well-balanced amino acid profile. However, anti-nutritional factors such as antigen proteins and soybean agglutinin in soybean meal can also cause intestinal barrier injury and inflammatory reactions in fish, harming fish growth, immunity, and intestinal health. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The designed vaccine construct comprises 274 amino acid long sequences having a molecular weight of 28.14 kDa and instability index of 27.62. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Polar metabolites including disaccharides, nucleic acids, organic acids, inositols, and amino acids also increased in abundance upon rewetting. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Glyphosate prevents the synthesis of aromatic amino acids by inhibiting the Shikimate pathway, which, besides killing weeds, can also inhibit bacterial growth and promote bacterial dysbiosis. …”
Enlace del recurso
Enlace del recurso

“…Two base changes at positions 6624 (A to C) and 6739 (A to G) did not result in alteration in the amino acid sequence, and therefore 100% amino acid identity could be confirmed. …”
Enlace del recurso
Enlace del recurso