Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models

por Jacob, Sheeba, Turner, Tia H, Cai, Jinyang, Floros, Konstantinos V, Yu, Ann K, Coon, Colin M, Khatri, Rishabh, Alzubi, Mohammad A, Jakubik, Charles T, Bouck, Ynes M, Puchalapalli, Madhavi, Shende, Mayuri, Dozmorov, Mikhail G, Boikos, Sosipatros A, Hu, Bin, Harrell, J Chuck, Benes, Cyril H, Koblinski, Jennifer E, Costa, Carlotta, Faber, Anthony C
Publicado 2022

RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions

por Hogstad, Brandon, Berres, Marie-Luise, Chakraborty, Rikhia, Tang, Jun, Bigenwald, Camille, Serasinghe, Madhavika, Lim, Karen Phaik Har, Lin, Howard, Man, Tsz-Kwong, Remark, Romain, Baxter, Samantha, Kana, Veronika, Jordan, Stefan, Karoulia, Zoi, Kwan, Wing-hong, Leboeuf, Marylene, Brandt, Elisa, Salmon, Helene, McClain, Kenneth, Poulikakos, Poulikos, Chipuk, Jerry, Mulder, Willem J.M., Allen, Carl E., Merad, Miriam
Publicado 2018

An Adjusted Treatment Comparison Comparing Amivantamab Versus Real-World Clinical Practice in Europe and the United States for Patients with Advanced Non-Small Cell Lung Cancer wit...

por Chouaid, Christos, Bosquet, Lise, Girard, Nicolas, Kron, Anna, Scheffler, Matthias, Griesinger, Frank, Sebastian, Martin, Trigo, Jose, Viteri, Santiago, Knott, Craig, Rodrigues, Bernardo, Rahhali, Nora, Cabrieto, Jedelyn, Diels, Joris, Perualila, Nolen J., Schioppa, Claudio A., Sermon, Jan, Toueg, Raphael, Erdmann, Nicole, Mielke, Janka, Nematian-Samani, Mehregan, Martin-Fernandez, Cristina, Pfaira, Innocent, Li, Tracy, Mahadevia, Parthiv, Wolf, Jürgen
Publicado 2023

Large language models encode clinical knowledge

por Singhal, Karan, Azizi, Shekoofeh, Tu, Tao, Mahdavi, S. Sara, Wei, Jason, Chung, Hyung Won, Scales, Nathan, Tanwani, Ajay, Cole-Lewis, Heather, Pfohl, Stephen, Payne, Perry, Seneviratne, Martin, Gamble, Paul, Kelly, Chris, Babiker, Abubakr, Schärli, Nathanael, Chowdhery, Aakanksha, Mansfield, Philip, Demner-Fushman, Dina, Agüera y Arcas, Blaise, Webster, Dale, Corrado, Greg S., Matias, Yossi, Chou, Katherine, Gottweis, Juraj, Tomasev, Nenad, Liu, Yun, Rajkomar, Alvin, Barral, Joelle, Semturs, Christopher, Karthikesalingam, Alan, Natarajan, Vivek
Publicado 2023

Publisher Correction: Large language models encode clinical knowledge

por Singhal, Karan, Azizi, Shekoofeh, Tu, Tao, Mahdavi, S. Sara, Wei, Jason, Chung, Hyung Won, Scales, Nathan, Tanwani, Ajay, Cole-Lewis, Heather, Pfohl, Stephen, Payne, Perry, Seneviratne, Martin, Gamble, Paul, Kelly, Chris, Babiker, Abubakr, Schärli, Nathanael, Chowdhery, Aakanksha, Mansfield, Philip, Demner-Fushman, Dina, Agüera y Arcas, Blaise, Webster, Dale, Corrado, Greg S., Matias, Yossi, Chou, Katherine, Gottweis, Juraj, Tomasev, Nenad, Liu, Yun, Rajkomar, Alvin, Barral, Joelle, Semturs, Christopher, Karthikesalingam, Alan, Natarajan, Vivek
Publicado 2023

A cross-sectional multicenter linkage study of hospital admissions and mortality due to methanol poisoning in Iranian adults during the COVID-19 pandemic

por Mahdavi, Seyed Amirhosein, Zamani, Nasim, McDonald, Rebecca, Akhgari, Maryam, Kolahi, Ali-Asghar, Gheshlaghi, Farzad, Ostadi, Ali, Dehghan, Ahmad, Moshiri, Mohammad, Rahbar-Taramsari, Morteza, Delirrad, Mohammad, Mohtasham, Neda, Afzali, Saeed, Ebrahimi, Sara, Ziaeefar, Pardis, Khosravi, Navid, Kazemifar, Amir Mohammad, Ghadirzadeh, Mohammadreza, Farajidana, Hoorvash, Barghemadi, Tahereh, Sadeghi, Farangis, Hadeiy, Seyed Kaveh, Hadipourzadeh, Mehdi, Mesbahi, Javad, Malekpour, Mohammad-Reza, Arabi, Mohsen, Jamshidi, Farkhondeh, Dadpour, Bita, Hovda, Knut Erik, Hassanian-Moghaddam, Hossein
Publicado 2022

Endovascular equipoise shift in a phase III randomized clinical trial of sonothrombolysis for acute ischemic stroke

por Alexandrov, Andrei V., Tsivgoulis, Georgios, Köhrmann, Martin, Katsanos, Aristeidis H., Soinne, Lauri, Barreto, Andrew D., Rothlisberger, Travis, Sharma, Vijay K., Mikulik, Robert, Muir, Keith W., Levi, Christopher R., Molina, Carlos A., Saqqur, Maher, Mavridis, Dimitris, Psaltopoulou, Theodora, Vosko, Milan R., Fiebach, Jochen B., Mandava, Pitchaiah, Kent, Thomas A., Alexandrov, Anne W., Schellinger, Peter D.
Publicado 2019

Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia

por Liu, Yiman, Li, Qinglan, Alikarami, Fatemeh, Barrett, Declan R., Mahdavi, Leila, Li, Hangpeng, Tang, Sylvia, Khan, Tanweer A., Michino, Mayako, Hill, Connor, Song, Lele, Yang, Lu, Li, Yuanyuan, Pokharel, Sheela Pangeni, Stamford, Andrew W., Liverton, Nigel, Renzetti, Louis M., Taylor, Simon, Watt, Gillian F., Ladduwahetty, Tammy, Kargman, Stacia, Meinke, Peter T., Foley, Michael A., Shi, Junwei, Li, Haitao, Carroll, Martin, Chen, Chun-Wei, Gardini, Alessandro, Maillard, Ivan, Huggins, David J., Bernt, Kathrin M., Wan, Liling
Publicado 2022

IL-12Rβ1 Deficiency in Two of Fifty Children with Severe Tuberculosis from Iran, Morocco, and Turkey

por Boisson-Dupuis, Stéphanie, El Baghdadi, Jamila, Parvaneh, Nima, Bousfiha, Aziz, Bustamante, Jacinta, Feinberg, Jacqueline, Samarina, Arina, Grant, Audrey V., Janniere, Lucile, El Hafidi, Naima, Hassani, Amal, Nolan, Daniel, Najib, Jilali, Camcioglu, Yildiz, Hatipoglu, Nevin, Aydogmus, Cigdem, Tanir, Gonul, Aytekin, Caner, Keser, Melike, Somer, Ayper, Aksu, Guside, Kutukculer, Necil, Mansouri, Davood, Mahdaviani, Alireza, Mamishi, Setareh, Alcais, Alexandre, Abel, Laurent, Casanova, Jean-Laurent
Publicado 2011

ARES: a spectrometer for investigation of rare particle decays and rare nuclear processes

por Baranov, V, Chernyavsky, M M, Evtoukhovitch, P G, Filippov, A T, Fursov, A P, Glazov, A A, Khomutov, N V, Kisel, I V, Korenchenko, A S, Korenchenko, S M, Kostin, B F, Kravuchuk, N P, Kuchinskii, N A, Moiseenko, A S, Mzhavia, D A, Nekrasov, K G, Povinec, P, Szarka, I, Smirnov, V S, Tsamalaidze, Z B, Vanko, J, Yakovlev, S L, Zyazyulya, F E
Publicado 1994

Distinct mesenchymal cell states mediate prostate cancer progression

por Pakula, Hubert, Omar, Mohamed, Carelli, Ryan, Pederzoli, Filippo, Fanelli, Giuseppe Nicolò, Pannellini, Tania, Van Emmenis, Lucie, Rodrigues, Silvia, Fidalgo-Ribeiro, Caroline, Nuzzo, Pier V., Brady, Nicholas J., Jere, Madhavi, Unkenholz, Caitlin, Alexanderani, Mohammad K., Khani, Francesca, de Almeida, Francisca Nunes, Abate-Shen, Cory, Greenblatt, Matthew B, Rickman, David S., Barbieri, Christopher E., Robinson, Brian D., Marchionni, Luigi, Loda, Massimo
Publicado 2023

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

por Poulikakos, Poulikos I., Persaud, Yogindra, Janakiraman, Manickam, Kong, Xiangju, Ng, Charles, Moriceau, Gatien, Shi, Hubing, Atefi, Mohammad, Titz, Bjoern, Gabay, May Tal, Salton, Maayan, Dahlman, Kimberly B., Tadi, Madhavi, Wargo, Jennifer A., Flaherty, Keith T., Kelley, Mark C., Misteli, Tom, Chapman, Paul B., Sosman, Jeffrey A., Graeber, Thomas G., Ribas, Antoni, Lo, Roger S., Rosen, Neal, Solit, David B.
Publicado 2011

Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence

por Furches, Anna, Kainer, David, Weighill, Deborah, Large, Annabel, Jones, Piet, Walker, Angelica M., Romero, Jonathon, Gazolla, Joao Gabriel Felipe Machado, Joubert, Wayne, Shah, Manesh, Streich, Jared, Ranjan, Priya, Schmutz, Jeremy, Sreedasyam, Avinash, Macaya-Sanz, David, Zhao, Nan, Martin, Madhavi Z., Rao, Xiaolan, Dixon, Richard A., DiFazio, Stephen, Tschaplinski, Timothy J., Chen, Jin-Gui, Tuskan, Gerald A., Jacobson, Daniel
Publicado 2019

Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1

por Kurupi, Richard, Floros, Konstantinos V., Jacob, Sheeba, Chawla, Ayesha T., Cai, Jinyang, Hu, Bin, Puchalapalli, Madhavi, Coon, Colin M., Khatri, Rishabh, Crowther, Giovanna Stein, Egan, Regina K., Murchie, Ellen, Greninger, Patricia, Dalton, Krista M., Ghotra, Maninderjit S., Boikos, Sosipatros A., Koblinski, Jennifer E., Harada, Hisashi, Sun, Yue, Morgan, Iain M., Basu, Devraj, Dozmorov, Mikhail G., Benes, Cyril H., Faber, Anthony C.
Publicado 2022

Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer

por Simoneau, Antoine, Engel, Justin L., Bandi, Madhavi, Lazarides, Katherine, Liu, Shangtao, Meier, Samuel R., Choi, Ashley H., Zhang, Hongxiang, Shen, Binzhang, Martires, Lauren, Gotur, Deepali, Pham, Truc V., Li, Fang, Gu, Lina, Gong, Shanzhong, Zhang, Minjie, Wilker, Erik, Pan, Xuewen, Whittington, Douglas A., Throner, Scott, Maxwell, John P., Chen, Yingnan, Yu, Yi, Huang, Alan, Andersen, Jannik N., Feng, Tianshu
Publicado 2023

Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex

por Huuki-Myers, Louise, Spangler, Abby, Eagles, Nick, Montgomery, Kelsey D., Kwon, Sang Ho, Guo, Boyi, Grant-Peters, Melissa, Divecha, Heena R., Tippani, Madhavi, Sriworarat, Chaichontat, Nguyen, Annie B., Ravichandran, Prashanthi, Tran, Matthew N., Seyedian, Arta, Hyde, Thomas M., Kleinman, Joel E., Battle, Alexis, Page, Stephanie C., Ryten, Mina, Hicks, Stephanie C., Martinowich, Keri, Collado-Torres, Leonardo, Maynard, Kristen R.
Publicado 2023

A13 THE RATE OF ADVERSE EVENTS AFTER COVID-19 VACCINATION IS SIMILAR IN PATIENTS WITH CELIAC DISEASE AND NON-CELIAC POPULATION: RESULTS OF A LARGE INTERNATIONAL CROSS-SECTIONAL STU...

por Tandon, S, Stefanolo, J P, Russell, L, Paz Temprano, M D L, Niveloni, S, Verdu, E, Armstrong, D, Lebwohl, B, Leffler, D, Tye-Din, J, Day, A, Olano, C, Lopez, V, Uzcanga, L, Madaria, E, Montoro Huguet, M, Vivas, S, Rodriguez-Herrera, A, Makharia, G, Sanders, D, Zeitz, J, Mulder, C, Ciacci, C, Valerio, F, Pinto-Sanchez, M I
Publicado 2023

Incidence of Malignancy after Living Kidney Transplantation: A Multicenter Study from Iran

por Einollahi, Behzad, Rostami, Zohreh, Nourbala, Mohammad Hossein, Lessan-Pezeshki, Mahboob, Simforoosh, Naser, Nemati, Eghlim, Pourfarziani, Vahid, Beiraghdar, Fatemeh, Nafar, Mohsen, Pour-Reza-Gholi, Fatemeh, Mazdeh, Mitra Mahdavi, Amini, Manochehr, Ahmadpour, Pedram, Makhdoomi, Khadijeh, Ghafari, Ali, Ardalan, Mohammad Reza, Khosroshahi, Hamid Taebi, Oliaei, Farshid, Shahidi, Shahrzad, Abbaszadeh, Shahin, Fatahi, Mohammad Reza, Hiedari, Fatemeh, Makhlogh, Atehieh, Azmandian, Jalal, Samimagham, Hamid Reza, Shahbazian, Heshmatollah, Nazemian, Fatemeh, Naghibi, Massih, Khosravi, Masoud, Monfared, Ali, Mosavi, Seyed Majid, Ahmadi, Javad, Jalalzadeh, Mojgan
Publicado 2012

Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates

por White, Andrew D., Tran, Andy C., Sibley, Laura, Sarfas, Charlotte, Morrison, Alexandra L., Lawrence, Steve, Dennis, Mike, Clark, Simon, Zadi, Sirine, Lanni, Faye, Rayner, Emma, Copland, Alastair, Hart, Peter, Diogo, Gil Reynolds, Paul, Matthew J., Kim, Miyoung, Gleeson, Fergus, Salguero, Francisco J., Singh, Mahavir, Stehr, Matthias, Cutting, Simon M., Basile, Juan I., Rottenberg, Martin E., Williams, Ann, Sharpe, Sally A., Reljic, Rajko
Publicado 2023

Creating a role model for “Academicians” Social Responsibility (ASR) synergizing with Swachh Bharat Abhiyaan: A campus hygiene initiative by PGIMER, Chandigarh

por Anand, Akshay, Banik, Avijit, Minhas, Gillipsie, Bammidi, Sridhar, Thakur, Keshav, Sharma, Kaushal, Tyagi, Rahul, Modgil, Shweta, Bali, Parul, Sayal, Natasha, Kaur, Paramvir, Pal, Deepak Kumar, Goyal, Atul Kumar, Bhatt, Vinod, Kaur, Navneet, Kumar, Saurabh, Saini, Jyoti, Kaushal, Sushant, Tiwari, Abha, Ghani, Abdul, Kaur, Gurkeerat, Devi, Chandra, Battu, Priya, Khosla, Radhika, Sharma, Kanupriya, Sivapuram, Madhava Sai, Podder, Vivek, Singh, Amarjeet, Mehra, Priya
Publicado 2019