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1261“…Mouse mammary tumor virus (MMTV) has previously been shown to encode a functional homolog of the human immunodeficiency virus-1 (HIV-1) nuclear export protein Rev, termed Rem. …”
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1262por Uva, Paolo, Aurisicchio, Luigi, Watters, James, Loboda, Andrey, Kulkarni, Amit, Castle, John, Palombo, Fabio, Viti, Valentina, Mesiti, Giuseppe, Zappulli, Valentina, Marconato, Laura, Abramo, Francesca, Ciliberto, Gennaro, Lahm, Armin, La Monica, Nicola, de Rinaldis, Emanuele“…RESULTS: We analyzed human and dog gene expression data derived from both tumor and normal mammary samples. By analyzing the expression levels of about ten thousand dog/human orthologous genes we observed a significant overlap of genes deregulated in the mammary tumor samples, as compared to their normal counterparts. …”
Publicado 2009
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1263por Gyorki, David E, Asselin-Labat, Marie-Liesse, van Rooijen, Nico, Lindeman, Geoffrey J, Visvader, Jane E“…INTRODUCTION: Macrophages in the mammary gland are essential for morphogenesis of the ductal epithelial tree and have been implicated in promoting breast tumor metastasis. …”
Publicado 2009
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1264“…This review will concentrate on Myc as a signaling mediator in the mammary gland, discussing its regulation and function during normal development, as well as its activation and roles in breast cancer.…”
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1265“…4T1 mouse mammary tumor cells can be implanted sub-cutaneously in nu/nu mice to form palpable tumors in 15 to 20 days. …”
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1266por Weng, Desheng, Cunin, Monique C, Song, Baizheng, Price, Brendan D, Eller, Mark S, Gilchrest, Barbara A, Calderwood, Stuart K, Gong, Jianlin“…T-oligo also caused radiosensitization in two in vivo mammary tumor models. Indeed, combined T-oligo and IR-treatment in vivo led to a substantial reduction in tumor growth. …”
Publicado 2010
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1267“…The mammary gland is a unique organ that continually undergoes postnatal developmental changes. …”
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1268por Wagh, Purnima K., Gray, Jerilyn K., Zinser, Glendon M., Vasiliauskas, Juozas, James, Laura, Monga, Satdarshan P.S., Waltz, Susan E.“…Our previous studies demonstrated that selective overexpression of the Ron receptor tyrosine kinase in the murine mammary epithelium leads to mammary tumor formation. …”
Publicado 2011
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1269por Rajkumar, Lakshmanaswamy, Guzman, Raphael C, Yang, Jason, Thordarson, Gudmundur, Talamantes, Frank, Nandi, Satyabrata“…Short-term exposure to ethynyl estradiol plus megesterol acetate or norethindrone was effective in decreasing the incidence of mammary cancers. Tamoxifen plus progesterone treatment for 3 weeks was able to confer only a transient protection from mammary carcinogenesis, while 2-methoxy estradiol plus progesterone was effective in conferring protection against mammary cancers. …”
Publicado 2004
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1270“…RESULTS: In this study we report the characterization of several cell lines established from mammary tumors that develop in MTB-IGFIR transgenic mice. …”
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1271“…Studies in rodent models of breast cancer show that exposures to dietary/hormonal factors during the in utero and pubertal periods, when the mammary gland undergoes extensive modeling and re-modeling, alter susceptibility to carcinogen-induced mammary tumors. …”
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1272por Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J“…Importantly, mouse mammary tumors were found to carry fewer structural rearrangements than human mammary cancers and expressed in-frame fusion genes. …”
Publicado 2010
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1273por Prosperi, Jenifer R., Khramtsov, Andrey I., Khramtsova, Galina F., Goss, Kathleen H.“…In mouse models, Apc mutation disrupts normal mammary development and predisposes to mammary tumor formation; however, the cooperation between APC and other mutations in breast tumorigenesis has not been studied. …”
Publicado 2011
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1274por Yang, Hai Jie, Lee, Eun-Mi, Kim, Ah-Young, Lee, Eun-Joo, Hong, IL-Hwa, Huh, Sung-Oh, Jeong, Kyu-Shik“…An eleven-year-old spayed female Yorkshire Terrier presented with a sublumbar mass and upon ultrasonographic examination, was revealed to have a mammary gland tumor. Black to reddish colored masses, located in the visceral peritoneum of the sublumbar region was observed on laparotomy with masectomy of the right side. …”
Publicado 2011
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1275por Blanchard, Zannel, Malik, Rohit, Mullins, Nicole, Maric, Christine, Luk, Hugh, Horio, David, Hernandez, Brenda, Killeen, Jeffrey, ElShamy, Wael M.“…Geminin overexpressing human mammary epithelial cells form aneuploid, aggressive tumors in SCID mice. …”
Publicado 2011
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1277por Shull, JD, Schaffer, BS, Bartsch, LM, Buckles, LK, Gould, KA, Tochacek, M, Xie, B, Lachel, CM, Pennington, KL, Strecker, TE, Hansen, KKEnlace del recurso
Publicado 2003
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1278por Rosen, JM, Welm, BE, Tepera, SB, Behbod, F, Grimm, SL, Venezia, T, Goodell, MA, Graubert, TA, Werb, Z, Li, Y, Varmus, HEEnlace del recurso
Publicado 2003
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