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30321por Okiring, Jaffer, Gonahasa, Samuel, Nassali, Martha, Namuganga, Jane F., Bagala, Irene, Maiteki‑Sebuguzi, Catherine, Opigo, Jimmy, Nabende, Isaiah, Nangendo, Joanita, Kabami, Jane, Ssewanyana, Isaac, Kiwuwa, Steven M., Nankabirwa, Joaniter I., Dorsey, Grant, Briggs, Jessica, Kamya, Moses R., Staedke, Sarah G.“…METHODS: During April–May 2021, households were randomly selected from target areas (1–7 villages) surrounding 12 government-run health facilities established as Malaria Reference Centres; at least 50 households were enrolled per cluster. …”
Publicado 2022
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30322por Ge, Jieyun, Wang, Qiubo, Chen, Gangcheng, Kassegne, Kokouvi, Zhang, Hangye, Yu, Jiali, Tang, Jianxia, Wang, Bo, Lu, Feng, Cao, Jun, Han, Eun-Taek, Cheng, Yang“…BACKGROUND: Plasmodium vivax rhoptry-associated membrane antigen (RAMA) is a glycophosphatidylinositol-anchored membrane protein currently under consideration as a malaria vaccine candidate. Immunoglobulin G (IgG) antibodies induced by P. vivax RAMA (PvRAMA) have been proved to persist over 12 months in the sera of people infected with P. vivax. …”
Publicado 2022
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30323por Anthonj, Carmen, Githinji, Sophie, Höser, Christoph, Stein, Alfred, Blanford, Justine, Grossi, Valentina“…RESULTS: The books comprehensively address drinking water issues, including sources, quality, treatment, safe storage and water conservation; risks and transmission pathways of various waterborne (Cholera, Typhoid fever), water-based (Bilharzia), vector-related (Malaria) and other communicable diseases (Tuberculosis); and the importance of environmental hygiene and health promotion. …”
Publicado 2021
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30324por Youmbi, Laetitia M., Makong, Yves S. D., Mbaveng, Armelle T., Tankeo, Simplice B., Fotso, Ghislain W., Ndjakou, Bruno L., Wansi, Jean D., Beng, Veronique P., Sewald, Norbert, Ngadjui, Bonaventure T., Efferth, Thomas, Kuete, Victor“…Brucea antidysenterica is an African medicinal plant traditionally used to treat cancer, dysentery, malaria, diarrhea, stomach aches, helminthic infections, fever, and asthma. …”
Publicado 2023
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30325por Mohammed, Nuredin I., Wason, James, Mendy, Thomas, Nass, Stefan A., Ofordile, Ogochukwu, Camara, Famalang, Baldeh, Bakary, Sanyang, Chilel, Jallow, Amadou T., Hossain, Ilias, Faria, Nuno, Powell, Jonathan J., Prentice, Andrew M., Pereira, Dora I.A.“…Secondary endpoints reported herein include hospitalisation, acute respiratory infection, malaria, treatment failures, iron handling markers, inflammatory markers, longitudinal prevalence of diarrhoea and incidence density of bloody diarrhoea. …”
Publicado 2023
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30326por Gaggiano, Carla, Del Bianco, Alessandra, Sota, Jurgen, Gentileschi, Stefano, Ruscitti, Piero, Giacomelli, Roberto, Piga, Matteo, Crisafulli, Francesca, Monti, Sara, Emmi, Giacomo, De Paulis, Amato, Vitale, Antonio, Tarsia, Maria, Caggiano, Valeria, Nuzzolese, Rossana, Parretti, Veronica, Fabiani, Claudia, Lopalco, Giuseppe, Maier, Armin, Cattalini, Marco, Rigante, Donato, Govoni, Marcello, Li Gobbi, Francesca, Guiducci, Serena, Parronchi, Paola, Marino, Achille, Ciccia, Francesco, Maggio, Maria Cristina, Aragona, Emma, Bartoloni, Elena, Iagnocco, Annamaria, Viapiana, Ombretta, Sebastiani, Gian Domenico, Guerriero, Silvana, Insalaco, Antonella, Del Giudice, Emanuela, Conti, Giovanni, Barone, Patrizia, Olivieri, Alma Nunzia, Brucato, Antonio, Carubbi, Francesco, Triggianese, Paola, Mauro, Angela, Tosi, Gian Marco, Fonollosa, Alex, Giardini, Henrique Ayres Mayrink, Ragab, Gaafar, Tharwat, Samar, Hernández-Rodríguez, José, Sfikakis, Petros P., Laskari, Katerina, Karamanakos, Anastasios, Espinosa, Gerard, Shahram, Farhad, Direskeneli, Haner, Hinojosa-Azaola, Andrea, Opris-Belinski, Daniela, AlMaghlouth, Ibrahim A., Hatemi, Gülen, Eksin, Mehmet Akif, Önen, Fatos, Więsik-Szewczyk, Ewa, Akkoç, Nurullah, Tufan, Abdurrahman, Şahin, Ali, Erten, Şükran, Ozen, Seza, Batu, Ezgi Deniz, Frediani, Bruno, Balistreri, Alberto, Cantarini, Luca“…METHODS: The project was coordinated by the University of Siena and the Italian patient advocacy organization SIMBA (Associazione Italiana Sindrome e Malattia di Behçet), in the context of the AIDA (AutoInflammatory Diseases Alliance) Network programme. …”
Publicado 2023
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30327por Madanitsa, Mwayiwawo, Barsosio, Hellen C, Minja, Daniel T R, Mtove, George, Kavishe, Reginald A, Dodd, James, Saidi, Queen, Onyango, Eric D, Otieno, Kephas, Wang, Duolao, Ashorn, Ulla, Hill, Jenny, Mukerebe, Crispin, Gesase, Samwel, Msemo, Omari A, Mwapasa, Victor, Phiri, Kamija S, Maleta, Kenneth, Klein, Nigel, Magnussen, Pascal, Lusingu, John P A, Kariuki, Simon, Mosha, Jacklin F, Alifrangis, Michael, Hansson, Helle, Schmiegelow, Christentze, Gutman, Julie R, Chico, R Matthew, ter Kuile, Feiko O“…BACKGROUND: Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin–piperaquine is more effective than IPTp with sulfadoxine–pyrimethamine at reducing malaria infection during pregnancy in areas with high-grade resistance to sulfadoxine–pyrimethamine by Plasmodium falciparum in east Africa. …”
Publicado 2023
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30328por Mbabazi, Joseph, Pesu, Hannah, Mutumba, Rolland, Filteau, Suzanne, Lewis, Jack I., Wells, Jonathan C., Olsen, Mette F., Briend, André, Michaelsen, Kim F., Mølgaard, Christian, Ritz, Christian, Nabukeera-Barungi, Nicolette, Mupere, Ezekiel, Friis, Henrik, Grenov, Benedikte“…Eleven serious adverse events occurred in 10 (1.3%) children, mainly hospitalization with malaria and anemia, all deemed unrelated to the intervention. …”
Publicado 2023
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30329por Perrotti, Edvige, L’Episcopia, Mariangela, Menegon, Michela, Soares, Irene S., Rosas-Aguirre, Angel, Speybroeck, Niko, LLanos-Cuentas, Alejandro, Menard, Didier, Ferreira, Marcelo Urbano, Severini, Carlo“…The low variability of the sequence encoding PvETRAMP11.2 protein suggests that it would be a suitable marker in prospective serodiagnostic assays for surveillance strategies or in vaccine design against P. vivax malaria. METHODS: The pvetramp11.2 of P. vivax isolates collected from Brazil (n = 68) and Peru (n = 36) were sequenced and analyzed to assess nucleotide polymorphisms, allele distributions, population differentiation, genetic diversity and signature of selection. …”
Publicado 2023
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30330por Tsegaye, Arega, Demissew, Assalif, Hawaria, Dawit, Abossie, Ashenafi, Getachew, Hallelujah, Habtamu, Kassahun, Degefa, Teshome, Wang, Xiaoming, Lee, Ming-Chieh, Zhou, Guofa, Yewhalaw, Delenasaw, Yan, Guiyun“…When coupled with behavioural resistances, a shift in malaria vector feeding and resting behaviours could compromise the effectiveness of the current adult vector control strategies. …”
Publicado 2023
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30331por Flegg, Jennifer A, Guérin, Philippe J, Nosten, Francois, Ashley, Elizabeth A, Phyo, Aung Pyae, Dondorp, Arjen M, Fairhurst, Rick M, Socheat, Duong, Borrmann, Steffen, Björkman, Anders, Mårtensson, Andreas, Mayxay, Mayfong, Newton, Paul N, Bethell, Delia, Se, Youry, Noedl, Harald, Diakite, Mahamadou, Djimde, Abdoulaye A, Hien, Tran T, White, Nicholas J, Stepniewska, Kasia“…BACKGROUND: The emergence of Plasmodium falciparum resistance to artemisinins in Southeast Asia threatens the control of malaria worldwide. The pharmacodynamic hallmark of artemisinin derivatives is rapid parasite clearance (a short parasite half-life), therefore, the in vivo phenotype of slow clearance defines the reduced susceptibility to the drug. …”
Publicado 2013
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30332por Robinson, Leanne J., Wampfler, Rahel, Betuela, Inoni, Karl, Stephan, White, Michael T., Li Wai Suen, Connie S. N., Hofmann, Natalie E., Kinboro, Benson, Waltmann, Andreea, Brewster, Jessica, Lorry, Lina, Tarongka, Nandao, Samol, Lornah, Silkey, Mariabeth, Bassat, Quique, Siba, Peter M., Schofield, Louis, Felger, Ingrid, Mueller, Ivo“…BACKGROUND: The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. …”
Publicado 2015
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30333por van der Kam, Saskia, Salse-Ubach, Nuria, Roll, Stephanie, Swarthout, Todd, Gayton-Toyoshima, Sayaka, Jiya, Nma Mohammed, Matsumoto, Akiko, Shanks, Leslie“…A three-armed, partially-blinded, randomised controlled trial was conducted in children diagnosed as having malaria, diarrhoea, or lower respiratory tract infection. …”
Publicado 2016
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30334por Pantoja, Tomas, Opiyo, Newton, Lewin, Simon, Paulsen, Elizabeth, Ciapponi, Agustín, Wiysonge, Charles S, Herrera, Cristian A, Rada, Gabriel, Peñaloza, Blanca, Dudley, Lilian, Gagnon, Marie‐Pierre, Garcia Marti, Sebastian, Oxman, Andrew D“…Strategies targeted at healthcare recipients: mass media interventions to increase uptake of HIV testing; intensive self‐management and adherence, intensive disease management programmes to improve health literacy; behavioural interventions and mobile phone text messages for adherence to antiretroviral therapy; a one time incentive to start or continue tuberculosis prophylaxis; default reminders for patients being treated for active tuberculosis; use of sectioned polythene bags for adherence to malaria medication; community‐based health education, and reminders and recall strategies to increase vaccination uptake; interventions to increase uptake of cervical screening (invitations, education, counselling, access to health promotion nurse and intensive recruitment); health insurance information and application support. …”
Publicado 2017
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30335por Keitel, Kristina, Kagoro, Frank, Samaka, Josephine, Masimba, John, Said, Zamzam, Temba, Hosiana, Mlaganile, Tarsis, Sangu, Willy, Rambaud-Althaus, Clotilde, Gervaix, Alain, Genton, Blaise, D’Acremont, Valérie“…Current disease management tools, such as the Integrated Management of Childhood Illness (IMCI) algorithm, rely solely on clinical signs and have not made use of available point-of-care tests (POCTs) that can help to identify children with severe infections and children in need of antibiotic treatment. e-POCT is a novel electronic algorithm based on current evidence; it guides clinicians through the entire consultation and recommends treatment based on a few clinical signs and POCT results, some performed in all patients (malaria rapid diagnostic test, hemoglobin, oximeter) and others in selected subgroups only (C-reactive protein, procalcitonin, glucometer). …”
Publicado 2017
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30336por Ogunleye, Olayinka O., Basu, Debashis, Mueller, Debjani, Sneddon, Jacqueline, Seaton, R. Andrew, Yinka-Ogunleye, Adesola F., Wamboga, Joshua, Miljković, Nenad, Mwita, Julius C., Rwegerera, Godfrey Mutashambara, Massele, Amos, Patrick, Okwen, Niba, Loveline Lum, Nsaikila, Melaine, Rashed, Wafaa M., Hussein, Mohamed Ali, Hegazy, Rehab, Amu, Adefolarin A., Boahen-Boaten, Baffour Boaten, Matsebula, Zinhle, Gwebu, Prudence, Chirigo, Bongani, Mkhabela, Nongabisa, Dlamini, Tenelisiwe, Sithole, Siphiwe, Malaza, Sandile, Dlamini, Sikhumbuzo, Afriyie, Daniel, Asare, George Awuku, Amponsah, Seth Kwabena, Sefah, Israel, Oluka, Margaret, Guantai, Anastasia N., Opanga, Sylvia A., Sarele, Tebello Violet, Mafisa, Refeletse Keabetsoe, Chikowe, Ibrahim, Khuluza, Felix, Kibuule, Dan, Kalemeera, Francis, Mubita, Mwangana, Fadare, Joseph, Sibomana, Laurien, Ramokgopa, Gwendoline Malegwale, Whyte, Carmen, Maimela, Tshegofatso, Hugo, Johannes, Meyer, Johanna C., Schellack, Natalie, Rampamba, Enos M., Visser, Adel, Alfadl, Abubakr, Malik, Elfatih M., Malande, Oliver Ombeva, Kalungia, Aubrey C., Mwila, Chiluba, Zaranyika, Trust, Chaibva, Blessmore Vimbai, Olaru, Ioana D., Masuka, Nyasha, Wale, Janney, Hwenda, Lenias, Kamoga, Regina, Hill, Ruaraidh, Barbui, Corrado, Bochenek, Tomasz, Kurdi, Amanj, Campbell, Stephen, Martin, Antony P., Phuong, Thuy Nguyen Thi, Thanh, Binh Nguyen, Godman, Brian“…The World Health Organization (WHO) warns that a lack of nets and treatment could result in up to 18 million additional cases of malaria and up to 30,000 additional deaths in sub-Saharan Africa. …”
Publicado 2020
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30337Publicado 2020“…Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). …”
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30338Publicado 2021“…Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0·80 (95% UI 0·71–0·86) deaths per 1000 livebirths and U5MR to 1·44 (95% UI 1·27–1·58) deaths per 1000 livebirths, and in 2019, there were as many as 1·87 million (95% UI 1·35–2·58; 37% [95% UI 32–43]) of 5·05 million more deaths of children younger than 5 years than the survival potential frontier. …”
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30339por Sutcliffe, Alice C., Irish, Seth R., Rogier, Eric, Finney, Micaela, Zohdy, Sarah, Dotson, Ellen M.“…BACKGROUND: Plasmodium spp. sporozoite rates in mosquitoes are used to better understand malaria transmission intensity, the relative importance of vector species and the impact of interventions. …”
Publicado 2021
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30340por Breiman, Robert F., Blau, Dianna M., Mutevedzi, Portia, Akelo, Victor, Mandomando, Inacio, Ogbuanu, Ikechukwu U., Sow, Samba O., Madrid, Lola, El Arifeen, Shams, Garel, Mischka, Thwala, Nana Bukiwe, Onyango, Dickens, Sitoe, Antonio, Bassey, Ima-Abasi, Keita, Adama Mamby, Alemu, Addisu, Alam, Muntasir, Mahtab, Sana, Gethi, Dickson, Varo, Rosauro, Ojulong, Julius, Samura, Solomon, Mehta, Ashka, Ibrahim, Alexander M., Rahman, Afruna, Vitorino, Pio, Baillie, Vicky L., Agaya, Janet, Tapia, Milagritos D., Assefa, Nega, Chowdhury, Atique Iqbal, Scott, J. Anthony G., Gurley, Emily S., Kotloff, Karen L., Jambai, Amara, Bassat, Quique, Tippett-Barr, Beth A., Madhi, Shabir A., Whitney, Cynthia G.“…Among 46 child deaths with malnutrition as the underlying condition, all had ≥1 other condition in the causal chain, most commonly sepsis, followed by LRI, malaria, and diarrheal disease. Including all positions in the causal chain for neonatal deaths resulted in 19-fold and 11-fold increases in attributable roles for meningitis and LRI, respectively. …”
Publicado 2021
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