Immune checkpoint modulation enhances HIV-1 antibody induction

por Bradley, Todd, Kuraoka, Masayuki, Yeh, Chen-Hao, Tian, Ming, Chen, Huan, Cain, Derek W., Chen, Xuejun, Cheng, Cheng, Ellebedy, Ali H., Parks, Robert, Barr, Maggie, Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Bouton-Verville, Hilary, Santra, Sampa, Wiehe, Kevin, Lewis, Mark G., Ogbe, Ane, Borrow, Persephone, Montefiori, David, Bonsignori, Mattia, Anthony Moody, M., Verkoczy, Laurent, Saunders, Kevin O., Ahmed, Rafi, Mascola, John R., Kelsoe, Garnett, Alt, Frederick W., Haynes, Barton F.
Publicado 2020

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

por Sheahan, Timothy P., Sims, Amy C., Zhou, Shuntai, Graham, Rachel L., Pruijssers, Andrea J., Agostini, Maria L., Leist, Sarah R., Schäfer, Alexandra, Dinnon, Kenneth H., Stevens, Laura J., Chappell, James D., Lu, Xiaotao, Hughes, Tia M., George, Amelia S., Hill, Collin S., Montgomery, Stephanie A., Brown, Ariane J., Bluemling, Gregory R., Natchus, Michael G., Saindane, Manohar, Kolykhalov, Alexander A., Painter, George, Harcourt, Jennifer, Tamin, Azaibi, Thornburg, Natalie J., Swanstrom, Ronald, Denison, Mark R., Baric, Ralph S.
Publicado 2020

Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection

por Jeong, Hye Won, Kim, Se-Mi, Jung, Min Kyung, Noh, Ji Yun, Yoo, Ji-Seung, Kim, Eun-Ha, Kim, Young-Il, Yu, Kwangmin, Jang, Seung-Gyu, Gil, Juryeon, Casel, Mark Anthony, Rare, Rollon, Choi, Jeong Ho, Kim, Hee-Sung, Kim, Jun Hyoung, Um, Jihye, Kim, Chaeyoon, Kim, Yeonjae, Chin, Bum Sik, Jung, Sungmin, Choi, Jun Yong, Song, Kyoung-Ho, Kim, Yong-Dae, Park, Jun-Sun, Song, Joon Young, Shin, Eui-Cheol, Choi, Young Ki
Publicado 2022

Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques

por Yu, Jingyou, Collins, Natalie D., Mercado, Noe B., McMahan, Katherine, Chandrashekar, Abishek, Liu, Jinyan, Anioke, Tochi, Chang, Aiquan, Giffin, Victoria M., Hope, David L., Sellers, Daniel, Nampanya, Felix, Gardner, Sarah, Barrett, Julia, Wan, Huahua, Velasco, Jason, Teow, Elyse, Cook, Anthony, Van Ry, Alex, Pessaint, Laurent, Andersen, Hanne, Lewis, Mark G., Hofer, Christian, Burke, Donald S., Barkei, Erica K., King, Hannah A. D., Subra, Caroline, Bolton, Diane, Modjarrad, Kayvon, Michael, Nelson L., Barouch, Dan H.
Publicado 2022

Single-Shot Ad26 Vaccine Protects Against SARS-CoV-2 in Rhesus Macaques

por Mercado, Noe B., Zahn, Roland, Wegmann, Frank, Loos, Carolin, Chandrashekar, Abishek, Yu, Jingyou, Liu, Jinyan, Peter, Lauren, McMahan, Katherine, Tostanoski, Lisa H., He, Xuan, Martinez, David R., Rutten, Lucy, Bos, Rinke, van Manen, Danielle, Vellinga, Jort, Custers, Jerome, Langedijk, Johannes P., Kwaks, Ted, Bakkers, Mark J.G., Zuijdgeest, David, Huber, Sietske K. Rosendahl, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Hoffman, Emily, Jacob-Dolan, Catherine, Kirilova, Marinela, Li, Zhenfeng, Lin, Zijin, Mahrokhian, Shant H., Maxfield, Lori F., Nampanya, Felix, Nityanandam, Ramya, Nkolola, Joseph P., Patel, Shivani, Ventura, John D., Verrington, Kaylee, Wan, Huahua, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Strasbaugh, Amanda, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Zouantchangadou, Serge, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Cai, Yongfei, Chen, Bing, Schmidt, Aaron G., Reeves, R. Keith, Baric, Ralph S., Lauffenburger, Douglas A., Alter, Galit, Stoffels, Paul, Mammen, Mathai, Van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2020

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression

por Liu, Jing, Ottaviani, Daniela, Sefta, Meriem, Desbrousses, Céline, Chapeaublanc, Elodie, Aschero, Rosario, Sirab, Nanor, Lubieniecki, Fabiana, Lamas, Gabriela, Tonon, Laurie, Dehainault, Catherine, Hua, Clément, Fréneaux, Paul, Reichman, Sacha, Karboul, Narjesse, Biton, Anne, Mirabal-Ortega, Liliana, Larcher, Magalie, Brulard, Céline, Arrufat, Sandrine, Nicolas, André, Elarouci, Nabila, Popova, Tatiana, Némati, Fariba, Decaudin, Didier, Gentien, David, Baulande, Sylvain, Mariani, Odette, Dufour, Florent, Guibert, Sylvain, Vallot, Céline, Rouic, Livia Lumbroso-Le, Matet, Alexandre, Desjardins, Laurence, Pascual-Pasto, Guillem, Suñol, Mariona, Catala-Mora, Jaume, Llano, Genoveva Correa, Couturier, Jérôme, Barillot, Emmanuel, Schaiquevich, Paula, Gauthier-Villars, Marion, Stoppa-Lyonnet, Dominique, Golmard, Lisa, Houdayer, Claude, Brisse, Hervé, Bernard-Pierrot, Isabelle, Letouzé, Eric, Viari, Alain, Saule, Simon, Sastre-Garau, Xavier, Doz, François, Carcaboso, Angel M., Cassoux, Nathalie, Pouponnot, Celio, Goureau, Olivier, Chantada, Guillermo, de Reyniès, Aurélien, Aerts, Isabelle, Radvanyi, François
Publicado 2021

Breakthrough SARS-CoV-2 infections with the delta (B.1.617.2) variant in vaccinated patients with immune-mediated inflammatory diseases using immunosuppressants: a substudy of two...

por Boekel, Laura, Stalman, Eileen W, Wieske, Luuk, Hooijberg, Femke, van Dam, Koos P J, Besten, Yaëlle R, Kummer, Laura Y L, Steenhuis, Maurice, van Kempen, Zoé L E, Killestein, Joep, Volkers, Adriaan G, Tas, Sander W, van der Kooi, Anneke J, Raaphorst, Joost, Löwenberg, Mark, Takkenberg, R Bart, D'Haens, Geert R A M, Spuls, Phyllis I, Bekkenk, Marcel W, Musters, Annelie H, Post, Nicoline F, Bosma, Angela L, Hilhorst, Marc L, Vegting, Yosta, Bemelman, Frederike J, Voskuyl, Alexandre E, Broens, Bo, Parra Sanchez, Agner, van Els, Cécile A C M, de Wit, Jelle, Rutgers, Abraham, de Leeuw, Karina, Horváth, Barbara, Verschuuren, Jan J G M, Ruiter, Annabel M, van Ouwerkerk, Lotte, van der Woude, Diane, Allaart, Cornelia F, Teng, Y K Onno, van Paassen, Pieter, Busch, Matthias H, Jallah, Papay B P, Brusse, Esther, van Doorn, Pieter A, Baars, Adája E, Hijnen, Dirk Jan, Schreurs, Corine R G, van der Pol, W Ludo, Goedee, H Stephan, Vogelzang, Erik H, Leeuw, Maureen, Atiqi, Sadaf, van Vollenhoven, Ronald, Gerritsen, Martijn, van der Horst-Bruinsma, Irene E, Lems, Willem F, Nurmohamed, Mike T, Boers, Maarten, Keijzer, Sofie, Keijser, Jim, van de Sandt, Carolien, Boogaard, Arend, Cristianawati, Olvi, ten Brinke, Anja, Verstegen, Niels J M, Zwinderman, Koos A H, van Ham, S Marieke, Rispens, Theo, Kuijpers, Taco W, Wolbink, Gertjan, Eftimov, Filip
Publicado 2022

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

por Baum, Alina, Ajithdoss, Dharani, Copin, Richard, Zhou, Anbo, Lanza, Kathryn, Negron, Nicole, Ni, Min, Wei, Yi, Mohammadi, Kusha, Musser, Bret, Atwal, Gurinder S., Oyejide, Adelekan, Goez-Gazi, Yenny, Dutton, John, Clemmons, Elizabeth, Staples, Hilary M., Bartley, Carmen, Klaffke, Benjamin, Alfson, Kendra, Gazi, Michal, Gonzalez, Olga, Dick, Edward, Carrion, Ricardo, Pessaint, Laurent, Porto, Maciel, Cook, Anthony, Brown, Renita, Ali, Vaneesha, Greenhouse, Jack, Taylor, Tammy, Andersen, Hanne, Lewis, Mark G., Stahl, Neil, Murphy, Andrew J., Yancopoulos, George D., Kyratsous, Christos A.
Publicado 2020

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

por Parzych, Elizabeth M., Du, Jianqiu, Ali, Ali R., Schultheis, Katherine, Frase, Drew, Smith, Trevor R. F., Cui, Jiayan, Chokkalingam, Neethu, Tursi, Nicholas J., Andrade, Viviane M., Warner, Bryce M., Gary, Ebony N., Li, Yue, Choi, Jihae, Eisenhauer, Jillian, Maricic, Igor, Kulkarni, Abhijeet, Chu, Jacqueline D., Villafana, Gabrielle, Rosenthal, Kim, Ren, Kuishu, Francica, Joseph R., Wootton, Sarah K., Tebas, Pablo, Kobasa, Darwyn, Broderick, Kate E., Boyer, Jean D., Esser, Mark T., Pallesen, Jesper, Kulp, Dan W., Patel, Ami, Weiner, David B.
Publicado 2022

Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques

por He, Xuan, Chandrashekar, Abishek, Zahn, Roland, Wegmann, Frank, Yu, Jingyou, Mercado, Noe B., McMahan, Katherine, Martinot, Amanda J., Piedra-Mora, Cesar, Beecy, Sidney, Ducat, Sarah, Chamanza, Ronnie, Huber, Sietske Rosendahl, van Heerden, Marjolein, van der Fits, Leslie, Borducchi, Erica N., Lifton, Michelle, Liu, Jinyan, Nampanya, Felix, Patel, Shivani, Peter, Lauren, Tostanoski, Lisa H., Pessaint, Laurent, Van Ry, Alex, Finneyfrock, Brad, Velasco, Jason, Teow, Elyse, Brown, Renita, Cook, Anthony, Andersen, Hanne, Lewis, Mark G., Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2021

Robust and prototypical immune responses toward influenza vaccines in the high-risk group of Indigenous Australians

por Hensen, Luca, Nguyen, Thi H. O., Rowntree, Louise C., Damelang, Timon, Koutsakos, Marios, Aban, Malet, Hurt, Aeron, Harland, Kim L., Auladell, Maria, van de Sandt, Carolien E., Everitt, Anngie, Blacker, Cath, Oyong, Damian A., Loughland, Jessica R., Webb, Jessica R., Wines, Bruce D., Hogarth, P. Mark, Flanagan, Katie L., Plebanski, Magdalena, Wheatley, Adam, Chung, Amy W., Kent, Stephen J., Miller, Adrian, Clemens, E. Bridie, Doherty, Peter C., Nelson, Jane, Davies, Jane, Tong, Steven Y. C., Kedzierska, Katherine
Publicado 2021

SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

por Lusvarghi, Sabrina, Pollett, Simon D., Neerukonda, Sabari Nath, Wang, Wei, Wang, Richard, Vassell, Russell, Epsi, Nusrat J., Fries, Anthony C, Agan, Brian K, Lindholm, David A., Colombo, Christopher J., Mody, Rupal, Ewers, Evan C., Lalani, Tahaniyat, Ganesan, Anuradha, Goguet, Emilie, Hollis-Perry, Monique, Coggins, Si’Ana A., Simons, Mark P., Katzelnick, Leah C., Wang, Gregory, Tribble, David R., Bentley, Lisa, Eakin, Ann E., Broder, Christopher C., Erlandson, Karl J., Laing, Eric D., Burgess, Timothy H., Mitre, Edward, Weiss, Carol D.
Publicado 2021

SARS-CoV-2 BA.1 variant is neutralized by vaccine booster-elicited serum, but evades most convalescent serum and therapeutic antibodies

por Lusvarghi, Sabrina, Pollett, Simon D., Neerukonda, Sabari Nath, Wang, Wei, Wang, Richard, Vassell, Russell, Epsi, Nusrat J., Fries, Anthony C., Agan, Brian K., Lindholm, David A., Colombo, Christopher J., Mody, Rupal, Ewers, Evan C., Lalani, Tahaniyat, Ganesan, Anuradha, Goguet, Emilie, Hollis-Perry, Monique, Coggins, Si’Ana A., Simons, Mark P., Katzelnick, Leah C., Wang, Gregory, Tribble, David R., Bentley, Lisa, Eakin, Ann E., Broder, Christopher C., Erlandson, Karl J., Laing, Eric D., Burgess, Timothy H., Mitre, Edward, Weiss, Carol D.
Publicado 2022

Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals following mRNA vaccination

por Goel, Rishi R., Apostolidis, Sokratis A., Painter, Mark M., Mathew, Divij, Pattekar, Ajinkya, Kuthuru, Oliva, Gouma, Sigrid, Hicks, Philip, Meng, Wenzhao, Rosenfeld, Aaron M., Dysinger, Sarah, Lundgreen, Kendall A., Kuri-Cervantes, Leticia, Adamski, Sharon, Hicks, Amanda, Korte, Scott, Oldridge, Derek A., Baxter, Amy E., Giles, Josephine R., Weirick, Madison E., McAllister, Christopher M., Dougherty, Jeanette, Long, Sherea, D’Andrea, Kurt, Hamilton, Jacob T., Betts, Michael R., Luning Prak, Eline T., Bates, Paul, Hensley, Scott E., Greenplate, Allison R., Wherry, E. John
Publicado 2021

Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters

por Tostanoski, Lisa H., Chandrashekar, Abishek, Patel, Shivani, Yu, Jingyou, Jacob-Dolan, Catherine, Chang, Aiquan, Powers, Olivia C., Sellers, Daniel, Gardner, Sarah, Barrett, Julia, Sanborn, Owen, Stephenson, Kathryn E., Ansel, Jessica L., Jaegle, Kate, Seaman, Michael S., Porto, Maciel, Lok, Megan, Spence, Brittany, Cayer, Kathleen, Nase, Danielle, Holman, Shaikim, Bradette, Heath, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Cox, Freek, Tolboom, Jeroen T. B. M., de Groot, Anne Marit, Heerwegh, Dirk, Le Gars, Mathieu, Sadoff, Jerald, Wegmann, Frank, Zahn, Roland C., Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2022

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

por Chandrashekar, Abishek, Yu, Jingyou, McMahan, Katherine, Jacob-Dolan, Catherine, Liu, Jinyan, He, Xuan, Hope, David, Anioke, Tochi, Barrett, Julia, Chung, Benjamin, Hachmann, Nicole P., Lifton, Michelle, Miller, Jessica, Powers, Olivia, Sciacca, Michaela, Sellers, Daniel, Siamatu, Mazuba, Surve, Nehalee, VanWyk, Haley, Wan, Huahua, Wu, Cindy, Pessaint, Laurent, Valentin, Daniel, Van Ry, Alex, Muench, Jeanne, Boursiquot, Mona, Cook, Anthony, Velasco, Jason, Teow, Elyse, Boon, Adrianus C.M., Suthar, Mehul S., Jain, Neharika, Martinot, Amanda J., Lewis, Mark G., Andersen, Hanne, Barouch, Dan H.
Publicado 2022

Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses

por Dijokaite-Guraliuc, Aiste, Das, Raksha, Zhou, Daming, Ginn, Helen M., Liu, Chang, Duyvesteyn, Helen M.E., Huo, Jiandong, Nutalai, Rungtiwa, Supasa, Piyada, Selvaraj, Muneeswaran, de Silva, Thushan I., Plowright, Megan, Newman, Thomas A.H., Hornsby, Hailey, Mentzer, Alexander J., Skelly, Donal, Ritter, Thomas G., Temperton, Nigel, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Roemer, Cornelius, Peacock, Thomas P., Paterson, Neil G., Williams, Mark A., Hall, David R., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2023

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in non-human primates and has an extended half-life in humans

por Loo, Yueh-Ming, McTamney, Patrick M., Arends, Rosalinda H., Abram, Michael E., Aksyuk, Anastasia A., Diallo, Seme, Flores, Daniel J., Kelly, Elizabeth J., Ren, Kuishu, Roque, Richard, Rosenthal, Kim, Streicher, Katie, Tuffy, Kevin M., Bond, Nicholas J., Cornwell, Owen, Bouquet, Jerome, Cheng, Lily I., Dunyak, James, Huang, Yue, Rosenbaum, Anton I., Reddy, Venkatesh Pilla, Andersen, Hanne, Carnahan, Robert H., Crowe, James E., Kuehne, Ana I., Herbert, Andrew S., Dye, John M., Bright, Helen, Kallewaard, Nicole L., Pangalos, Menelas N., Esser, Mark T.
Publicado 2022

Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

por Montefiori, David C., Karnasuta, Chitraporn, Huang, Ying, Ahmed, Hasan, Gilbert, Peter, de Souza, Mark S., McLinden, Robert, Tovanabutra, Sodsai, Laurence-Chenine, Agnes, Sanders-Buell, Eric, Moody, M. Anthony, Bonsignori, Mattia, Ochsenbauer, Christina, Kappes, John, Tang, Haili, Greene, Kelli, Gao, Hongmei, LaBranche, Celia C., Andrews, Charla, Polonis, Victoria R., Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, Self, Steve G., Berman, Phillip W., Francis, Donald, Sinangil, Faruk, Lee, Carter, Tartaglia, Jim, Robb, Merlin L., Haynes, Barton F., Michael, Nelson L., Kim, Jerome H.
Publicado 2012

A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates

por Dalvie, Neil C., Tostanoski, Lisa H., Rodriguez-Aponte, Sergio A, Kaur, Kawaljit, Bajoria, Sakshi, Kumru, Ozan S., Martinot, Amanda J., Chandrashekar, Abishek, McMahan, Katherine, Mercado, Noe B., Yu, Jingyou, Chang, Aiquan, Giffin, Victoria M., Nampanya, Felix, Patel, Shivani, Bowman, Lesley, Naranjo, Christopher A., Yun, Dongsoo, Flinchbaugh, Zach, Pessaint, Laurent, Brown, Renita, Velasco, Jason, Teow, Elyse, Cook, Anthony, Andersen, Hanne, Lewis, Mark G., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Biswas, Sumi, Love, J. Christopher, Barouch, Dan H.
Publicado 2021