“…Plasmas from guinea pigs, chronically infected with group C hemolytic streptococci, neutralize the components of bacterial extract which exert a marked toxic action on hypersensitive cells in vitro. 2. …”
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“…Injection of formalin-treated, virus-free extracts containing considerable amounts of soluble antigen fails to elicit anti-soluble substance antibodies and to induce immunity in normal guinea pigs; administration of such preparations to immune pigs, however, is followed by a marked increase in the titer of anti-soluble substance antibodies in their serum. …”
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“…It was demonstrated that there are marked discrepancies in correlation between antibody titers obtained by in vitro hemagglutination-inhibition and in vivo neutralization techniques and that neutralizing antibody is preferentially absorbed by a given quantity of virus. …”
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“…Further, the intraperitoneal administration of these concentrations of fluoroacetate was found to inhibit markedly the propagation of influenza, Type A, virus in the lungs of mice. …”
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“…With Newcastle disease and influenza A, the slope of the neutralization line varies markedly with the host-cell system used and in the chick embryo is strikingly affected by the route of inoculation. …”
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“…Fv-1 was shown to have a marked suppressive effect on time of appearance of detectable infectious virus and on the titers attained in vivo, but did not affect the ability of the cells to produce virus in vitro after induction with 5-iododeoxyuridine. …”
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“…The exposure of cells to P-specific siRNAs also led to inhibition of virus replication as evidenced by marked reduction in the progeny virion titers. Taken together, the findings suggest that exogenous P silencing siRNAs can inhibit aMPV replication with potential implications in the design of novel siRNA based prophylactics.…”
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“…Type D, bacillus of rabbit septicemia, exhibits marked fixity of the character of virulence. This is true for cultures that are regularly transplanted on serum agar or in broth. …”
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“…There was a fall in complement titer by 1 min after Ab infusion that was due to complement consumption by the donor kidney. …”
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“…In bioactivity assays, LST-007 or titers of Cmax sera derived from pharmacokinetic studies, markedly attenuated PA motility in an equipotent manner. …”
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“…Next, the pedicled muscle flap was perfused with high titers of Ad.BMP-2 and Ad.GFP virus, respectively. …”
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“…WPCD effectively improved the titers of IgG, IgG(1) and IgG(2a) and markedly enhanced the proliferation of T and B cells, the production of IFN-γ and IL-4 in CD4(+) T cells and the expression level of IFN-γ in CD8(+) T cells better than Alum. …”
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“…Our findings show that the third vaccine dose improves the humoral response, but the wane of the anti-spike and neutralizing antibody titers over time is more marked in the neutralizing antibodies.…”
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“…When analyzing CR or not, the fitting of the binary logistic regression model including both PLA2R Ab titer and PLR (Hosmer–Lemeshow test: χ(2)=8.328, P = 0.402; OR (PLA2R Ab titer) = 1.002 (95% CI 1.000–1.004, P = 0.042); OR (PLR) = 1.006 (95% CI 0.999–1.013, P = 0.098)) was markedly better than that with only PLA2R Ab titer (Hosmer–Lemeshow test: χ(2)=13.885, P = 0.016). …”
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“…When CY-treated mice were given sheep red blood cells the serum hemagglutinin titers produced were significantly lower than those found when mice received SRBC but not CY. …”
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“…On the other hand, antibody titers to pH1N1 virus were highest in school children, which were followed by a gradual decrease in adult. …”
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“…Seroprevalence of antibodies against Pd, as well as antibody titers, was greater among little brown myotis than among four other species of cave-hibernating bats in North America, including species with markedly lower WNS mortality rates. …”
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“…Primary outcomes included serum anti-SARS-CoV-2 spike immunoglobulin G (IgG) titers and neutralizing antibody titers against B.1.1.7 (alpha), B.1.617.2 (delta), and B.1.1.529 (omicron) variants. …”
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“…RESULTS: The majority of HCMV miRNAs were markedly upregulated in the serum of fever patients. …”
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“…Surviving mice became persistently infected carriers, with high virus titers in blood and brain. Immunofluorescent examination of the brain showed that in CY-induced carriers infection was initially confined to the choroid plexus, ependyma, and leptomeninges, but over the next 30 days gradually spread to the neural parenchyma, most notably to the molecular layer of the cerebellum. …”
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