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  1. 1021
    “…However, when such females are injected with the molting hormone β-ecdysone a marked stimulation of this enzyme's activity is observable. …”
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    ECDYSONE-MEDIATED STIMULATION OF DOPA DECARBOXYLASE ACTIVITY AND ITS RELATIONSHIP TO OVARIAN DEVELOPMENT IN AEDES AEGYPTI
  2. 1022
    “…A West Nile virus titer was positive, and serial brain magnetic resonance imaging scans showed resolving abnormalities that paralleled his neurological examination. …”
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    The natural history of West Nile virus infection presenting with West Nile virus meningoencephalitis in a man with a prolonged illness: a case report
  3. 1023
    “…In humans, chronic inflammation, severe injury, infection and disease can result in changes in steroid hormone titers and delayed onset of puberty; however the pathway by which this occurs remains largely unknown. …”
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    Tissue Damage Disrupts Developmental Progression and Ecdysteroid Biosynthesis in Drosophila
  4. 1024
    “…Hemostatic studies showed prolonged activated partial thromboplastin time, decreased factor VIII coagulation, and a high factor VIII inhibitor titer; these findings led to a diagnosis of acquired hemophilia A for which he was treated with methylprednisolone and recombinant activated factor VII on admission. …”
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    Myelofibrosis and acquired hemophilia A: a case report
  5. 1025
    “…A second course of rituximab was necessary as autoantibody titers showed no change and as new antibodies were noted after treatment with rituximab and cyclophosphamide. …”
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    Electroretinographic improvement after rituximab therapy in a patient with autoimmune retinopathy
  6. 1026
    “…Subsequently, parasite serology showed a markedly elevated level of Schistosoma antibody titers, and cerebrospinal fluid analysis yielded normal results. …”
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    Neuroschistosomiasis mimicking lower back pain: case report of a rare differential diagnosis in a pediatric patient
  7. 1027
    “…Consequently, current vaccine formulations might not induce adequate protective immunity in poultry, and emergence of isolates with marked avidity for human-like receptors increases the zoonotic risk.…”
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    Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential
  8. 1028
    “…However, ZnCl(2) and ZnSO(4) markedly reduced viral titers as well as TGEV RNA and viral protein synthesis when applied during virus penetration and at different time points after viral cell entry. …”
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    Antiviral activity of zinc salts against transmissible gastroenteritis virus in vitro
  9. 1029
    “…The administration of the SphK1 activator, K6PC-5, or S1P, or the overexpression of SphK1 consistently exhibited striking inhibitory effects in EBOV-GP-driven entry in diverse cell lines. Finally, K6PC-5 markedly reduced the EBOV titer in infected cells and the de novo production of viral proteins. …”
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    The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection
  10. 1030
    “…Although mRNA vaccines induced the greatest magnitude of Omicron BA.1 and BA.2 plasma neutralizing activity, administration of a booster based on the Wuhan-Hu-1 spike sequence markedly increased neutralizing antibody titers and breadth against BA.1 and BA.2 across all vaccines evaluated. …”
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    Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines
  11. 1031
    “…Administration of a homologous or heterologous booster based on the Wuhan-Hu-1 spike sequence markedly increased neutralizing antibody titers and breadth against BA.1, BA.2, BA.2.12.1, BA.4, and BA.5 across all vaccines evaluated. …”
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    Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines
  12. 1032
    “…We use these circuits to program the secretion of human monoclonal antibodies and to control T-cell effector function marked by interferon-γ production. Antibody titers and interferon-γ concentrations significantly correlate with synthetic promoter strengths, providing a platform for programming gene expression and cellular function in diverse applications.…”
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    A synthetic transcription platform for programmable gene expression in mammalian cells
  13. 1033
    “…We demonstrated that in SA-deficient NahG tobacco the elevation of in planta GSH and GSSG levels either by exogenous GSH or by crossing with glutathione overproducing plants confers enhanced resistance to Tobacco mosaic virus (TMV) manifested as both reduced symptoms (i.e. suppression of hypersensitive-type localized necrosis) and lower virus titers. The beneficial effects of elevated GSH on TMV resistance was markedly stronger in NahG than in Xanthi NN leaves. …”
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    Glutathione Can Compensate for Salicylic Acid Deficiency in Tobacco to Maintain Resistance to Tobacco Mosaic Virus
  14. 1034
    “…In addition, EMB showed signs of lymphocytic endocarditis with infiltrates, marked thickening and fibrosis of the endocardium (Fig. 1). …”
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    Post-COVID morphologically proved endocarditis: infective and nonbacterial forms
  15. 1035
    “…Multivariate analysis reveals the presence of a unique pre-existing Fcγ-receptor-binding antibody profile in individuals that evolved broadly reactive hemagglutination inhibition activity (HAI), marked by the presence of elevated levels of pre-existing FCGR2B-binding antibodies. …”
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    Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination
  16. 1036
    “…Continuous passages in primary human amnion cell cultures of Coxsackie prototype viruses A-9, A-10, A-11, A-13, A-14, A-15, A-18, B-1, B-2, B-4, and B-5 increased the titers, hastened and enhanced cytopathic effect, and in varying degrees caused loss of virulence for newborn mice. …”
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    PATHOGENICITY FOR SUCKLING MICE OF COXSACKIE VIRUSES ADAPTED TO HUMAN AMNION CELLS
  17. 1037
    “…Neutralizing autoantibodies to type I, but not type II, interferons (IFNs) are found at high titers in almost every patient with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), a disease caused by AIRE gene mutations that lead to defects in thymic T-cell selection. …”
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    Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes
  18. 1038
    “…High levels of creatine kinase (97,000 IU/L) and high titer of anti-influenza A virus antibody (H3N2) (320 ×) with negative anti-influenza B virus antibody were observed. …”
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    Influenza A (H3N2)-induced rhabdomyolysis complicating anterior compartment syndrome: Serial changes in muscle MRI T2 fat suppression imaging
  19. 1039
    “…The factor VIII activity level was reduced to 1.2%, and the factor VIII inhibitor titer was 285.3 BU/mL, a diagnosis of acquired hemophilia A (AHA) was made. …”
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    Acquired hemophilia A developing cerebral infarction 36 days after the frequent administration of bypass hemostatic agents
  20. 1040
    “…He began treatment with rituximab, which reduced the rate of relapse markedly. Following discontinuation of rituximab, however, the patient experienced two successive optic neuritis attacks 2 and 4 months after B-lymphocyte restoration. …”
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    Rebound of relapses after discontinuation of rituximab in a patient with MOG-IgG1 positive highly relapsing optic neuritis: a case report
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