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  1. 1121
    “…A SPEAR-targeting strategy markedly reduces SARS-CoV-2 titer, suggesting a pan-sarbecoviral therapeutic modality.…”
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    A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon
  2. 1122
    “…Importantly, ribavirin markedly inhibited TBEV propagation, as evidenced by impairment of TBEV production and viral RNA replication. …”
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    Inhibition of tick-borne encephalitis virus in cell cultures by ribavirin
  3. 1123
    “…We found that the loss of these markers resulted in significantly lower viral titers but did not impact viral genome or protein accumulation. …”
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    HSV-1 exploits host heterochromatin for nuclear egress
  4. 1124
    “…Additionally, cTfh cells were positively correlated with neutralizing antibody titers. Our results suggest that CoronaVac vaccine–induced spike-specific T cells are capable of supporting humoral immunity for long-term immune protection.…”
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    Longitudinal analysis of memory Tfh cells and antibody response following CoronaVac vaccination
  5. 1125
    por Miller, Gail Lorenz, Stanley, W. M.
    Publicado 1944
    “…It was found that the temperature at which the test is conducted has a marked effect on the titer, whereas within the range of pH 6–8 the pH has a negligible effect. …”
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    QUANTITATIVE ASPECTS OF THE RED BLOOD CELL AGGLUTINATION TEST FOR INFLUENZA VIRUS
  6. 1126
    “…There was no demonstrable difference in time of appearance or titer of the antibody responses, i.e. precipitins, antistreptolysins, and opsonins between the normal and nutritionally deficient monkeys. …”
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    REACTIONS OF MONKEYS TO EXPERIMENTALLY INDUCED STREPTOCOCCUS HEMOLYTICUS, GROUP C, INFECTION : AN ANALYSIS OF THE RELATIVE RÔLES OF HUMORAL AND CELLULAR IMMUNITY UNDER CONDITIONS OF OPTIMAL OR DEFICIENT NUTRITION
  7. 1127
    “…However, the roles of C/EBP transcription factors have not been fully identified because of functional redundancy among family members. Using high titer–retroviral infection, we demonstrate that a dominant-negative C/EBP completely blocked the granulocyte–macrophage commitment of human myeloid progenitors. …”
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    Reciprocal Roles for CCAAT/Enhancer Binding Protein (C/EBP) and PU.1 Transcription Factors in Langerhans Cell Commitment
  8. 1128
    “…The B cell response was characterized by high titers of antibody specific for hCII, and a high degree of cross-reactivity with murine type II collagen. …”
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    An HLA-DR1 Transgene Confers Susceptibility to Collagen-induced Arthritis Elicited with Human Type II Collagen
  9. 1129
    “…Several mechanisms have been proposed to account for the marked increase in severity of human infections with avian compared to human influenza strains, including increased cytokine expression, poor immune response, and differences in target cell receptor affinity. …”
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    Exploring Cell Tropism as a Possible Contributor to Influenza Infection Severity
  10. 1130
    “…BACKGROUND: When scaling up lignocellulose-based ethanol production, the desire to increase the final ethanol titer after fermentation can introduce problems. …”
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    Effect of mixing on enzymatic hydrolysis of steam-pretreated spruce: a quantitative analysis of conversion and power consumption
  11. 1131
    “…Our data indicated that oral administration of IFN-transformed B. longum for 2 weeks after virus infection reduced significantly the severity of virus-induced myocarditis, markedly down regulated virus titers in the heart, and induced a T helper 1 cell pattern in the spleen and heart compared with controls. …”
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    Oral administration of interferon-α2b-transformed Bifidobacterium longum protects BALB/c mice against coxsackievirus B3-induced myocarditis
  12. 1132
    “…In addition, OVA-specific IgG1 titers were markedly increased in breast milk from allergic mothers (OVA-sensitized and OVA-unexposed mother: 11.0 ± 0.5, OVA-sensitized and OVA-exposed mother: 12.3 ± 0.3). …”
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    Oral Tolerance Induced by Transfer of Food Antigens via Breast Milk of Allergic Mothers Prevents Offspring from Developing Allergic Symptoms in a Mouse Food Allergy Model
  13. 1133
    “…The intensity of the inhibition directly correlated with the titer of anti-Amot antibodies induced by the vaccine. …”
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    A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors
  14. 1134
    “…Serum GITRL levels were markedly increased in patients with SLE compared with healthy controls (mean 401.3 ng/mL and 36.59 ng/mL, resp.; P < 0.0001). …”
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    Correlation of Circulating Glucocorticoid-Induced TNFR-Related Protein Ligand Levels with Disease Activity in Patients with Systemic Lupus Erythematosus
  15. 1135
    “…The toxicity on a normal human liver cell (Chang liver cell) was determined using the CellTiter-Blue cell viability assay, and the compounds contained in the fractions were identified using GC-MS. …”
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    Evaluation of the Antibacterial and Antifungal Potential of Peltophorum africanum: Toxicological Effect on Human Chang Liver Cell Line
  16. 1136
    “…Almost all the mice died post challenge when xylitol or RGs were administered separately. Survival was markedly enhanced when xylitol was administered along with RGs, pointing to a synergistic effect. …”
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    Protective Effect of Dietary Xylitol on Influenza A Virus Infection
  17. 1137
    “…The patient’s symptoms improved markedly after a 5-day-course of high-dose glucocorticoid therapy. …”
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    Paraneoplastic brainstem encephalitis in a patient with exceptionally long course of a metastasized neuroendocrine rectum neoplasm
  18. 1138
    “…Other investigations showed leukocytopenia with lymphopenia, reduced IgG(2) and IgA levels, and low titers of specific postimmunization antibodies against tetanus toxoid and Haemophilus B polysaccharide. …”
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    A Precocious Cerebellar Ataxia and Frequent Fever Episodes in a 16-Month-Old Infant Revealing Ataxia-Telangiectasia Syndrome
  19. 1139
    “…With the use of precise gene editing, we further demonstrate that elongated O-glycans are essential for HSV-1 in human HaCaT keratinocytes, where HSV-1 produced markedly lower viral titers in HaCaT with abrogated O-glycans compared to the isogenic counterpart with normal O-glycans. …”
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    A Strategy for O-Glycoproteomics of Enveloped Viruses—the O-Glycoproteome of Herpes Simplex Virus Type 1
  20. 1140
    “…In contrast, combinatorial therapy using S1 and P28, one of six potent shRNAs, markedly reduced titers for both wild-type and T472C HBV. …”
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    Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice
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