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1201por Kuo, Tsun-Yung, Lin, Meei-Yun, Coffman, Robert L., Campbell, John D., Traquina, Paula, Lin, Yi-Jiun, Liu, Luke Tzu-Chi, Cheng, Jinyi, Wu, Yu-Chi, Wu, Chung-Chin, Tang, Wei-Hsuan, Huang, Chung-Guei, Tsao, Kuo-Chien, Chen, Charles“…S-2P in combination with CpG 1018 and aluminum hydroxide (alum) was found to be the most potent immunogen and induced high titer of neutralizing antibodies in sera of immunized mice against pseudotyped lentivirus reporter or live wild-type SARS-CoV-2. …”
Publicado 2020
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1202por Hirata, Hirohisa, Sakurai, Yoshihiko, Takeda, Tomohiro, Kasetani, Tetsuya, Morita, Takeshi“…Here, we report the case of a 43-year-old man who had marked prolongation of prothrombin time and activated partial thromboplastin time after surgery. …”
Publicado 2021
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1203por Kuchinsky, Sarah C., Frere, Francesca, Heitzman-Breen, Nora, Golden, Jacob, Vázquez, Ana, Honaker, Christa F., Siegel, Paul B., Ciupe, Stanca M., LeRoith, Tanya, Duggal, Nisha K.“…LAS chickens had significantly higher viral titers in blood and other tissues, as well as oral secretions, and significantly lower development of neutralizing antibody responses compared to HAS chickens. …”
Publicado 2021
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1204“…Surprisingly, CP treatment did not predict survival. Strikingly, marked decline in neutralization titers was observed in the fatal patients prior to death, and convalescent plasma treatment did not reverse this trend. …”
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1205por Stellavato, Antonietta, Restaino, Odile Francesca, Vassallo, Valentina, Cassese, Elisabetta, Finamore, Rosario, Ruosi, Carlo, Schiraldi, Chiara“…Inflammatory cytokines were markedly reduced by Ph while a slight decrease was only found for US-FS1.…”
Publicado 2021
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1206por Wang, Lin-Yue, Shen, Yan, Zeng, Han-Qing, Zhang, Ying, Lou, Shi-Feng, Deng, Jian-Chuan, Luo, Yun“…In all patients, FVIII activity levels were low (median: 1.5%; 1–3%), FVIII inhibitor titers were high (median: 24.5 BU/mL; 13.2–48.6 BU/mL), and activated partial thromboplastin time was markedly prolonged (median: 99.4 s; 60.9–110.1 s). …”
Publicado 2021
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1207por Nakano, Miki, Ayano, Masahiro, Kushimoto, Kazuo, Kawano, Shotaro, Higashioka, Kazuhiko, Inokuchi, Shoichiro, Mitoma, Hiroki, Kimoto, Yasutaka, Akahoshi, Mitsuteru, Ono, Nobuyuki, Arinobu, Yojiro, Akashi, Koichi, Horiuchi, Takahiko, Niiro, Hiroaki“…In SLE patients, sCD226 levels were significantly correlated with SLEDAI-2K scores and anti-dsDNA antibody titers. Moreover, the cumulative probability of flare was markedly higher in patients with high sCD226 than in those with low sCD226. …”
Publicado 2021
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1208por Muscarà, Claudia, Smeriglio, Antonella, Trombetta, Domenico, Mandalari, Giuseppina, La Camera, Erminia, Grassi, Gianpaolo, Circosta, Clara“…Gas chromatographic analysis showed that cannabinoids remained the predominant class of compounds in both extracts (82.56% and 86.38%, respectively), whereas a marked depletion of the terpenes occurred. Moreover, liquid chromatographic analysis highlighted a high titer of cannabidiol acid (CBDA) and CBD in CFHE1 and CFHE2, respectively. …”
Publicado 2021
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1209por Castanha, Priscila M S, Tuttle, Dylan J, Kitsios, Georgios D, Jacobs, Jana L, Braga-Neto, Ulisses, Duespohl, Matthew, Rathod, Sanjay, Marti, Michelle M, Wheeler, Sarah, Naqvi, Asma, Staines, Brittany, Mellors, John, Morris, Alison, McVerry, Bryan J, Shah, Faraaz, Schaefer, Caitlin, Macatangay, Bernard J C, Methe, Barbara, Fernandez, Christian A, Barratt-Boyes, Simon M, Burke, Donald, Marques, Ernesto T A“…We showed that plasma levels of C1q and circulating immune complexes were markedly increased in patients with severe COVID-19 and correlated with higher immunoglobulin (Ig) G titers, greater complement activation, and higher disease severity score. …”
Publicado 2022
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1210por Maritati, Federica, Bini, Claudia, Cuna, Vania, Tondolo, Francesco, Lerario, Sarah, Grandinetti, Valeria, Busutti, Marco, Corradetti, Valeria, La Manna, Gaetano, Comai, Giorgia“…The outcome in ABOi kidney transplantation have markedly improved over the years. In fact, although randomized trials are still lacking, recent meta analysis has revealed that there is no difference in terms of graft and patient’s survival between ABOi and ABO compatible kidney transplant, even in the long term. …”
Publicado 2022
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1211por Esseili, Malak A., Mann, Amy, Narwankar, Revati, Kassem, Issmat I., Diez-Gonzalez, Francisco, Hogan, Robert J.“…Therefore, on fresh berries infectious viruses are markedly inactivated over time and can be largely removed by washing with water. …”
Publicado 2022
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1212“…Here, we report that a high-titer HBV inoculum can be generated from the transient transfection-based cell model after optimizing transfection conditions and modifying the HBV-expressing construct. …”
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1213por Langalia, Akshay, Sinha, Nidhi, Thakker, Viral, Shah, Aarshvi, Shah, Jinali, Singh, Bijay“…Results indicated that saliva could be a reliable and financially viable option in both testing viral titers as well as marking for bio analytes due to its propitious specificity and sensitivity results reported in most of the studies. …”
Publicado 2022
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1214por Nurpeisova, Ainur, Khairullin, Berik, Abitaev, Ruslan, Shorayeva, Kamshat, Jekebekov, Kuanish, Kalimolda, Elina, Kerimbayev, Aslan, Akylbayeva, Karligash, Abay, Zhandos, Myrzakhmetova, Balzhan, Nakhanov, Aziz, Absatova, Zharkinay, Nurabayev, Sergazy, Orynbayev, Mukhit, Assanzhanova, Nurika, Abeuov, Khairulla, Kutumbetov, Lespek, Kassenov, Markhabat, Abduraimov, Yergaly, Zakarya, Kunsulu“…This study has demonstrated that a double immunization enhances the growth of antibody titers as assessed by the microneutralization assay (MNA) and the enzyme-linked immunosorbent assay (ELISA) in a pre-clinical immunogenicity test on animal models. …”
Publicado 2022
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1215Publicado 1993“…The administration of monoclonal antibodies to rat ICAM-1 and LFA-1 markedly decreased the severity of the renal disease. …”
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1216“…EBV envelope proteins including gH/gL, gB and gp350 play key roles in EBV entry and infection of target cells, and neutralizing antibodies elicited by each of these proteins have shown to prevent EBV infection of target cells and markedly decrease EBV titers in the peripheral blood of humanized mice challenged with lethal dose EBV. …”
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1217“…Interferon can be detected in the medium by 2 hr after viral infection and the titers usually reach a peak of 10,000 PDD(50)/ml by 4–6 hr. …”
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1218por Schäfer, Simon, Weibel, Stephanie, Donat, Ulrike, Zhang, Qian, Aguilar, Richard J, Chen, Nanhai G, Szalay, Aladar A“…This led to considerably elevated virus titers in GLV-1h255 infected tumors, and to enhanced tumor regression. …”
Publicado 2012
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1219por Hu, Zenglei, Zhao, Jiangyan, Zhao, Yiheng, Fan, Xuelian, Hu, Jiao, Shi, Lei, Wang, Xiaoquan, Liu, Xiaowen, Hu, Shunlin, Gu, Min, Cao, Yongzhong, Liu, Xiufan“…Despite inducing low levels of nAb, inactivated H7N9 vaccine conferred full protection against H7N9 challenge in chickens and markedly inhibited virus shedding. Similarly, Newcastle disease virus (NDV)-vectored H7N9 vaccine induced marginal HI and nAb titers but high level of IgG antibody against H7N9 virus. …”
Publicado 2020
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1220por Schilcher, Felix, Hilsmann, Lioba, Rauscher, Lisa, Değirmenci, Laura, Krischke, Markus, Krischke, Beate, Ankenbrand, Markus, Rutschmann, Benjamin, Mueller, Martin J., Steffan-Dewenter, Ingolf, Scheiner, Ricarda“…In addition, in vitro honeybees did not display the typical increase in juvenile hormone titer, which goes hand-in-hand with the initiation of foraging in colony-reared bees. …”
Publicado 2021
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