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1261por Barlev, Ashley N., Malkiel, Susan, Kurata-Sato, Izumi, Dorjée, Annemarie L., Suurmond, Jolien, Diamond, Betty“…Loss of FcγRIIB on B cells in Fcgr2b–conditional KO (Fcgr2b-cKO) mice led to a spontaneous increase in autoantibody titers. This increase was most striking for IgG3, suggestive of increased extrafollicular responses. …”
Publicado 2022
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1262por Liu, Dong, An, Chaoqiang, Bai, Yu, Li, Kelei, Liu, Jianyang, Wang, Qian, He, Qian, Song, Ziyang, Zhang, Jialu, Song, Lifang, Cui, Bopei, Mao, Qunying, Jiang, Wei, Liang, Zhenglun“…L2 plus Al with composite adjuvant compatibility with RBD markedly improved the immunogenicity of ZF2001; in particular, neutralizing antibody titers increased by about 44-fold for Omicron, and the combination also induced higher levels of antibodies than CpG 7909/poly(I:C) plus Al in mice. …”
Publicado 2022
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1263por Hsu, Fu-Fei, Liang, Kang-Hao, Kumari, Monika, Chen, Wan-Yu, Lin, Hsiu-Ting, Cheng, Chao-Min, Tao, Mi-Hua, Wu, Han-Chung“…Compared with traditional protein-based immunization approaches, inoculation of mice with RBD mRNA-LNP induced higher titers of serum antibodies and markedly increased serum neutralizing activity. …”
Publicado 2022
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1264por Fülöp, Gábor Áron, Lakatos, Bálint, Ruppert, Mihály, Kovács, Attila, Juhász, Vencel, Dér, Gábor, Tállay, András, Vágó, Hajnalka, Kiss, Boldizsár, Merkely, Béla, Zima, Endre“…Athletes were also tested for SARS-CoV-2 anti-nucleoprotein antibody titers, showing only modest increases following the second infection. …”
Publicado 2022
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1265por Panizo, Nayara, Giménez, Estela, Albert, Eliseo, Zulaica, Joao, Rodríguez-Moreno, Alicia, Rusu, Luciana, Giménez-Civera, Elena, Puchades, Maria Jesús, D’Marco, Luis, Gandía-Salmerón, Lorena, Torres, Ignacio, Sancho, Asunción, Gavela, Eva, Gonzalez-Rico, Miguel, Montomoli, Marco, Perez-Baylach, Carmen Maria, Bonilla, Begoña, Solano, Camila, Alvarado, Mª Fernanda, Torregrosa, Isidro, Gonzales-Candia, Boris, Alcaraz, María Jesús, Geller, Ron, Górriz, José Luis, Navarro, David“…The magnitude of the effect was more marked in HD than KTR patients.…”
Publicado 2022
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1266“…The fusion protein HA1-2-fliC and HA1-2 combined with PEI could induce significantly higher HA1-2-specific IgG and hemagglutination inhibition titers than HA1-2 alone at 12 days post-boost, with superior HA1-2 specific IgG titers in the HA1-2-fliC group compared with the PEI adjuvanted group. …”
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1267por Pani, Arianna, Cento, Valeria, Vismara, Chiara, Campisi, Daniela, Di Ruscio, Federica, Romandini, Alessandra, Senatore, Michele, Schenardi, Paolo Andrea, Gagliardi, Oscar Matteo, Giroldi, Simona, Zoppini, Laura, Moreno, Mauro, Corradin, Matteo, Epis, Oscar Massimiliano, Ughi, Nicola, Cuppari, Irene, Crocchiolo, Roberto, Merli, Marco, Bosio, Marco, Rossini, Silvano, Puoti, Massimo, Scaglione, Francesco“…Women had a higher probability of having higher titers than men (64.5% [1044/1618] vs 58.3% [410/703]; P=.005). …”
Publicado 2021
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1268por Pozo-Balado, María del Mar, Bulnes-Ramos, Ángel, Olivas-Martínez, Israel, Garrido-Rodríguez, Vanesa, Lozano, Carmen, Álvarez-Ríos, Ana I., Sánchez-Sánchez, Berta, Sánchez-Bejarano, Encarnación, Maldonado-Calzado, Isabel, Martín-Lara, José Manuel, Santamaría, Juan Antonio, Bernal, Rafael, González-Escribano, María Francisca, Leal, Manuel, Pacheco, Yolanda M.“…BACKGROUND: Older people achieve lower levels of antibody titers than younger populations after Covid-19 vaccination and show a marked waning humoral immunity over time, likely due to the senescence of the immune system. …”
Publicado 2023
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1269por Dahiya, Saurabh, Luetkens, Tim, Avila, Stephanie, Dahiya, Saurabh, Margiotta, Philip, Hankey, Kim, Lesho, Patricia, Bauman, Sherri, Smith, Nancy, Ruehle, Kathleen, Lee, Seung-Tae, Law, Jennie Y., Baddley, John, Kocoglu, Mehmet Hakan, Yared, Jean A., Hardy, Nancy M., Rapoport, Aaron P., Atanackovic, Djordje“…However, while at ~4 weeks post second dose of the vaccine the HCs showed marked antibody titers against all the viral spike proteins including their “delta” variants (Figure 2B), that was not the case for our CAR-T patients. …”
Publicado 2021
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1270por Sun, Zhihao, Wang, Qiuxia, Li, Gang, Li, Jingzhi, Chen, Sujuan, Qin, Tao, Ma, Hongwei, Peng, Daxin, Liu, Xiufan“…The recombinant H7N9 AIV with a modified epitope in the HA2 protein was rescued and named A/Chicken/Huadong/JD-cHA/17 (JD-cHA/17). The HA titer of JD-cHA/17 was 10 log(2), and the 50% egg infective dose (EID(50)) titer was 9.67 log(10) EID(50)/ml. …”
Publicado 2021
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1271por Nevo, Lea, Cahen-Peretz, Adva, Vorontsov, Olesya, Frenkel, Rachelli, Kabessa, Maor, Cohen, Sarah M., Hamrani, Adar, Oiknine-Djian, Esther, Lipschuetz, Michal, Goldman-Wohl, Debra, Walfisch, Asnat, Kovo, Michal, Neeman, Michal, Yagel, Simcha, Wolf, Dana G., Beharier, Ofer“…CONCLUSION: Postinfection maternal humoral immunity wanes during pregnancy, leading to low or undetectable protective titers for a marked proportion of patients. A single boosting dose of the BNT162b2 messenger RNA vaccine induced a robust increase in protective titers for both the mother and newborn with moderate reported side effects.…”
Publicado 2022
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1272por Yamamoto, Shohei, Matsuda, Kouki, Maeda, Kenji, Oshiro, Yusuke, Inamura, Natsumi, Mizoue, Tetsuya, Konishi, Maki, Takeuchi, Junko S., Horii, Kumi, Ozeki, Mitsuru, Sugiyama, Haruhito, Mitsuya, Hiroaki, Sugiura, Wataru, Ohmagari, Norio“…RESULTS: Breakthrough infection cases showed marked increases in NAb titers against Wild-type (4.1-fold) and Delta (5.5-fold), and 64% had detectable NAb against Omicron BA.1 at follow-up, although the NAb against Omicron after breakthrough infection was 6.7- and 5.2-fold lower than Wild-type and Delta, respectively. …”
Publicado 2023
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1273por Zhang, Xiaoyan, Sun, Chenxi, Hao, Jinfang, Cao, Li, Zhang, Xinyan, Du, Jianping, Han, Qian“…Enterovirus 71 (EV71) infection is one of the main causes of severe hand, foot and mouth disease (HFMD), which is usually accompanied by a marked inflammatory response. The excessive inflammatory response has been implicated to serve an important role in EV71-caused HFMD. …”
Publicado 2023
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1274“…Recovery of rabbits from severe burn infections was associated with the development of high titers of serum antibody to the alpha hemolysin or dermonecrotoxin of the staphylococcus. …”
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1275“…Insoluble blood group substances prepared by copolymerization of soluble blood group substances with N-carboxy-L-leucine anhydride were used to absorb blood group antibodies from two human, high-titered anti-A sera. After the absorbants were washed free of nonspecific serum proteins, blood group antibodies were eluted either with pH 3.62 acetate buffer, or at neutral pH with monosaccharide haptens of the A or B antigenic determinants (N-acetyl-D-galactosamine or D-galactose respectively). …”
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1276“…The effect of pituitary growth hormone on the biosynthesis of DNA in the thymus and other lymphoid organs, as well as the ability of the rat to respond immunologically to sheep red blood cells, has been evaluated. There is a marked reduction in plaque-forming cells, hemagglutination titers, and DNA synthesis in animals when examined at 15 wk after hypophysectomy. …”
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1277“…Immune spleen cells, when transferred to neonatal carriers, led to a decrease in virus titers in blood and brains and to development of antibody without acute CNS disease. …”
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1278“…A panel of serological tests for vasculitis were checked and showed elevated titers of cANCA and anti-proteinase 3 antibodies. …”
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1279por Sanchez, Carlos J., Hinojosa, Cecilia A., Shivshankar, Pooja, Hyams, Catherine, Camberlein, Emilie, Brown, Jeremy S., Orihuela, Carlos J.“…In mice challenged intraperitoneally, a marked reduction in bacterial blood titers was observed for those challenged with +6A and +7F versus +4 and +23F was undetectable. …”
Publicado 2011
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1280por Kar, Upendra K., Jiang, Janina, Champion, Cheryl I., Salehi, Sahar, Srivastava, Minu, Sharma, Sherven, Rabizadeh, Shahrooz, Niazi, Kayvan, Kickhoefer, Valerie, Rome, Leonard H., Kelly, Kathleen A.“…CONCLUSIONS/SIGNIFICANCE: These experiments show that vault nanocapsules induced strong anti-OVA CD8(+) and CD4(+) T cell memory responses and modest antibody production, which markedly differed from the immune response induced by liposomes. …”
Publicado 2012
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