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1421“…MLN Tfh frequency was markedly enhanced by chitosan-DNA, and was associated with VP1-specific IgA titer. 24 h after immunization, intranasal chitosan-DNA induced a recruitment of CD103(+)DCs into the MLN that paralleled a selective loss of CD103(+)DCs in the lamina propria (LP). …”
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1422SAT-354 Characterization of Cell Death Induced by SOAT1 Inhibition in Adrenocortical Carcinoma Cellspor Weigand, Isabel, Schreiner, Jochen, Roehrig, Florian, Hoefner, Kerstin, Kendl, Sabine, Fassnacht, Martin, Sbiera, Silviu, Kroiss, Matthias“…Methods: SOAT1 inhibition was quantified in vitro, ER-stress marker expression by qPCR, cell viability by cell titer glo assay, lipid composition by GC-MS, and lipid peroxidation with BODIPY 581/591 C11. …”
Publicado 2019
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1423por Li, Guomin, Li, Yifan, Liu, Haimei, Shi, Yu, Guan, Wanzhen, Zhang, Tao, Yao, Wen, Wu, Bingbing, Xu, Hong, Sun, Li“…B cell lymphoma (BCL)-2-interacting mediator of cell death levels in peripheral blood mononuclear cells from 4 patients were markedly reduced, whereas those in the control were normal. …”
Publicado 2020
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1424por Kothalawala, Shashika Dinethri, Edward, Daniya, Harasgama, Jayamini C., Ranaweera, Loshini, Weerasena, Ovitigala Vithanage Don Sisira Jagathpriya, Niloofa, Roshan, Ratnasooriya, Wanigasekera Daya, Premakumara, Galbada Arachchige Sirimal, Handunnetti, Shiroma M.“…Both HED and 1/2HED exhibited marked anti-inflammatory activity (72–83% inhibition at 4(th)-5(th) hours; p < 0.05). …”
Publicado 2020
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1425por DeMarco, Jennifer K, Severson, William E, DeMarco, Daniel R, Gabbard, Jon, Palmer, Kenneth E“…Finally, supernatants collected from naïve MPs subjected to ADE markedly increased the susceptibility of Vero E6 cells to SARS-CoV-2 nearly 9.8-fold (p< 0.0001). …”
Publicado 2020
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1426por Stephenson, Caroline J., Coatsworth, Heather, Kang, Seokyoung, Lednicky, John A., Dinglasan, Rhoel R.“…In a subsequent comparison with the recent COL mosquito colony, we also observed significantly higher midgut infection of COL and ORL by the Haitian DENV-4 field strain and a significantly higher saliva positivity rate for COL, although overall saliva virus titers were similar between the two. These data point to a potential midgut infection barrier for the DENV-4 laboratory strain for both mosquito colonies and indicate that the marked differences in transmission potential estimates hinge on virus-vector combinations. …”
Publicado 2021
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1427por Kurnianda, Johan, Hardianti, Mardiah S., Triyono, Teguh, Thobari, Jarir A., Trisnawati, Ika, Wisudarti, Calcarina F.R., Sukorini, Usi, Anshori, Fuad, Setiawan, Syahru A., Ucche, Meita, Farahnaz, Abrid, Suryani, Yana“…CONCLUSION: This study showed promising results for CP marked by improvements in clinical outcome, as well as significant reduction of inflammatory markers among recipients.…”
Publicado 2022
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1428por Okoroafor, Obianuju Nkiruka, Ogunniran, Temitope Mofoluso, Ikenna-Ezeh, Nkechi Harriet, Udeani, Ikechukwu John, Omeke, Jacinta Ngozi, Ezema, Wilfred Sunday, Anene, Boniface“…The activities of CAT and SOD were reduced markedly in the NDV-challenged chickens. Increases in the mean antibody titers were observed in the NDV-challenged group when compared with the UCCs from days 3 to 21 pi. …”
Publicado 2021
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1429por Abd El-Ghany, Wafaa A., Abdel-Latif, Mervat A., Hosny, Fouad, Alatfeehy, Nayera M., Noreldin, Ahmed E., Quesnell, Rebecca R., Chapman, Robert, Sakai, Lisa, Elbestawy, Ahmed R.“…Immunologically, the highest significant (P ≤ 0.05) hemagglutination inhibition antibody titers for Newcastle disease virus vaccine were in Gs 1 and 3 (6.4 log(2)). …”
Publicado 2022
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1430por Caserta, Leonardo C., Martins, Mathias, Cronk, Brittany, Anderson, Renee, Eldridge, Harry, Gallow, Deidre, Kruppa, Frank, Plocharczyk, Elizabeth, Diel, Diego G.“…Importantly, infectious virus loads were determined in a subset of samples and demonstrated shedding of high viral titers in respiratory secretions of vaccinated individuals.…”
Publicado 2022
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1431por Mazzio, Elizabeth, Barnes, Andrew, Badisa, Ramesh, Council, Stevie, Soliman, Karam F. A.“…This discovery led to the purposeful administration of the same attenuated strains, known as “Coley’s toxin,” marking the onset of the first microbial (pathogen) associated molecular pattern (MAMPs or PAMPs)-based tumor immunotherapy, used clinically for over four decades. …”
Publicado 2023
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1432Publicado 1980“…Strains which were positive at ICP and IP for anti-IgG had four-times higher serum levels of total IgA and two-times higher levels of total IgG than the corresponding negative strains from IC and JL. The anti-IgG titers differed markedly from one strain to the other in the same environment; e.g., in mice from ICP, BALB/c mice produced 40-times less anti-IgG than 129/Sv. …”
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1433“…Patients with human immunodeficiency virus 1–associated immunological thrombocytopenia (HIV-1–ITP) have markedly elevated platelet-bound immunoglobulin (Ig)G, IgM, and C3C4, as well as serum circulating immune complexes (CICs) composed of the same. …”
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1434por Alvarez-Oxiley, Andrea Vivian, de Sousa, Noelita Melo, Hornick, Jean-Luc, Touati, Kamal, van der Weijden, Gysbert C, Taverne, Marcel AM, Szenci, Otto, Beckers, Jean-François“…Polyclonal anti-bPL antibodies raised in rabbit were added in foetal sera to produce 100 samples with known antibodies titers (dilutions ranging from 1:2,500 till 1:1,280,000). …”
Publicado 2010
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1435por Levitz, Ruth, Wattier, Rachel, Phillips, Pamela, Solomon, Alexandra, Lawler, Jessica, Lazar, Isaac, Weibel, Carla, Kahn, Jeffrey S“…We chose two subgroup B strains, New Haven (NH)1067 and NH1125, for further analysis because of their marked differences in cytokine inducing properties and because subgroup B strains, in general, are less genetically heterogeneous as compared to subgroup A strains. …”
Publicado 2012
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1436por Gillard, Paul, Chu, Daniel Wai Sing, Hwang, Shinn-Jang, Yang, Pan-Chyr, Thongcharoen, Prasert, Lim, Fong Seng, Dramé, Mamadou, Walravens, Karl, Roman, François“…At Month 48, in subjects boosted at Month 6, 12, or 36, HI antibody titers of ≥1:40 against the booster strain persisted in 39.2%, 61.2%, and 95.6% of subjects, respectively. …”
Publicado 2014
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1437por Mazelier, Magalie, Rouxel, Ronan Nicolas, Zumstein, Michael, Mancini, Roberta, Bell-Sakyi, Lesley, Lozach, Pierre-Yves“…Furthermore, the amount of viral nucleoprotein per focus forming unit differed markedly whether viruses were produced in tick or BHK-21 cells, suggesting a higher infectivity for tick cell-derived viruses. …”
Publicado 2016
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1438por Buckingham, Erin M., Jarosinski, Keith W., Jackson, Wallen, Carpenter, John E., Grose, Charles“…The induction of autophagy in VZV-infected monolayers is easily detectable; inhibition of autophagy leads to decreased VZV glycoprotein biosynthesis and diminished viral titers. To explain how autophagic flux could exert a proviral effect on the VZV infectious cycle, we postulated that the VZV exocytosis pathway following secondary envelopment may converge with the autophagy pathway. …”
Publicado 2016
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1439por Bal, Jyotiranjan, Luong, Nguyen Ngoc, Park, Jisang, Song, Ki-Duk, Jang, Yong-Suk, Kim, Dae-Hyuk“…Sera from mice that were fed CFE preparations demonstrated markedly higher neutralizing titers compared to those from WC-fed mice. …”
Publicado 2018
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1440por Bröker, Katharina, Figge, Julia, Magnusen, Albert F., Manz, Rudolf A., Köhl, Jörg, Karsten, Christian M.“…Such stimulation also induced marked local C5 production by PerC macrophages and C5a generation. …”
Publicado 2018
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