Trastuzumab induced in vivo tissue remodelling associated in vitro with inhibition of the active forms of AKT and PTEN and RhoB induction in an ovarian carcinoma model

por Delord, J-P, Quideau, S, Rochaix, P, Caselles, O, Couderc, B, Hennebelle, I, Courbon, F, Canal, P, Allal, B C
Publicado 2010

DUSP16 is an epigenetically regulated determinant of JNK signalling in Burkitt's lymphoma

por Lee, S, Syed, N, Taylor, J, Smith, P, Griffin, B, Baens, M, Bai, M, Bourantas, K, Stebbing, J, Naresh, K, Nelson, M, Tuthill, M, Bower, M, Hatzimichael, E, Crook, T
Publicado 2010

Significance of E-cadherin expression in triple-negative breast cancer

por Kashiwagi, S, Yashiro, M, Takashima, T, Nomura, S, Noda, S, Kawajiri, H, Ishikawa, T, Wakasa, K, Hirakawa, K
Publicado 2010

The hypoxia-selective cytotoxin NLCQ-1 (NSC 709257) controls metastatic disease when used as an adjuvant to radiotherapy

por Lunt, S J, Cawthorne, C, Ali, M, Telfer, B A, Babur, M, Smigova, A, Julyan, P J, Price, P M, Stratford, I J, Bloomer, W D, Papadopoulou, M V, Williams, K J
Publicado 2010

BMS-690514, a VEGFR and EGFR tyrosine kinase inhibitor, shows anti-tumoural activity on non-small-cell lung cancer xenografts and induces sequence-dependent synergistic effect with...

por Loriot, Y, Mordant, P, Dorvault, N, De la motte Rouge, T, Bourhis, J, Soria, J-C, Deutsch, E
Publicado 2010

Plasma concentration of Propionibacterium acnes antibodies and prostate cancer risk: results from an Australian population-based case–control study

por Severi, G, Shannon, B A, Hoang, H N, Baglietto, L, English, D R, Hopper, J L, Pedersen, J, Southey, M C, Sinclair, R, Cohen, R J, Giles, G G
Publicado 2010

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer

por Lugli, A, Iezzi, G, Hostettler, I, Muraro, M G, Mele, V, Tornillo, L, Carafa, V, Spagnoli, G, Terracciano, L, Zlobec, I
Publicado 2010

Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis

por Xue, A, Scarlett, C J, Chung, L, Butturini, G, Scarpa, A, Gandy, R, Wilson, S R, Baxter, R C, Smith, R C
Publicado 2010

The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escal...

por Molife, L R, Fong, P C, Paccagnella, L, Reid, A H M, Shaw, H M, Vidal, L, Arkenau, H-T, Karavasilis, V, Yap, T A, Olmos, D, Spicer, J, Postel-Vinay, S, Yin, D, Lipton, A, Demers, L, Leitzel, K, Gualberto, A, de Bono, J S
Publicado 2010

Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases

por Cosimelli, M, Golfieri, R, Cagol, P P, Carpanese, L, Sciuto, R, Maini, C L, Mancini, R, Sperduti, I, Pizzi, G, Diodoro, M G, Perrone, M, Giampalma, E, Angelelli, B, Fiore, F, Lastoria, S, Bacchetti, S, Gasperini, D, Geatti, O, Izzo, F
Publicado 2010

Dual inhibition of EGFR and mTOR pathways in small cell lung cancer

por Schmid, K, Bago-Horvath, Z, Berger, W, Haitel, A, Cejka, D, Werzowa, J, Filipits, M, Herberger, B, Hayden, H, Sieghart, W
Publicado 2010

Alcohol intake and risk of colorectal cancer: Results from the UK Dietary Cohort Consortium

por Park, J Y, Dahm, C C, Keogh, R H, Mitrou, P N, Cairns, B J, Greenwood, D C, Spencer, E A, Fentiman, I S, Shipley, M J, Brunner, E J, Cade, J E, Burley, V J, Mishra, G D, Kuh, D, Stephen, A M, White, I R, Luben, R N, Mulligan, A A, Khaw, K-T, Rodwell, S A
Publicado 2010

Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan

por Okusaka, T, Nakachi, K, Fukutomi, A, Mizuno, N, Ohkawa, S, Funakoshi, A, Nagino, M, Kondo, S, Nagaoka, S, Funai, J, Koshiji, M, Nambu, Y, Furuse, J, Miyazaki, M, Nimura, Y
Publicado 2010

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis

por Edwards, S M, Evans, D G R, Hope, Q, Norman, A R, Barbachano, Y, Bullock, S, Kote-Jarai, Z, Meitz, J, Falconer, A, Osin, P, Fisher, C, Guy, M, Jhavar, S G, Hall, A L, O'Brien, L T, Gehr-Swain, B N, Wilkinson, R A, Forrest, M S, Dearnaley, D P, Ardern-Jones, A T, Page, E C, Easton, D F, Eeles, R A
Publicado 2010

Combination of osteopontin and activated leukocyte cell adhesion molecule as potent prognostic discriminators in HER2- and ER-negative breast cancer

por Ihnen, M, Wirtz, R M, Kalogeras, K T, Milde-Langosch, K, Schmidt, M, Witzel, I, Eleftheraki, A G, Papadimitriou, C, Jänicke, F, Briassoulis, E, Pectasides, D, Rody, A, Fountzilas, G, Müller, V
Publicado 2010

Prognostic significance of AMP-activated protein kinase expression and modifying effect of MAPK3/1 in colorectal cancer

por Baba, Y, Nosho, K, Shima, K, Meyerhardt, J A, Chan, A T, Engelman, J A, Cantley, L C, Loda, M, Giovannucci, E, Fuchs, C S, Ogino, S
Publicado 2010

Phase I and pharmacological study of the broad-spectrum tyrosine kinase inhibitor JNJ-26483327 in patients with advanced solid tumours

por Konings, I R H M, de Jonge, M J A, Burger, H, van der Gaast, A, van Beijsterveldt, L E C, Winkler, H, Verweij, J, Yuan, Z, Hellemans, P, Eskens, F A L M
Publicado 2010

Comparison of Hybrid capture 2 testing at different thresholds with cytology as primary cervical screening test

por Rijkaart, D C, Coupe, V M H, van Kemenade, F J, Heideman, D A M, Hesselink, A T, Verweij, W, Rozendaal, L, Verheijen, R H, Snijders, P J, Berkhof, J, Meijer, C J L M
Publicado 2010

Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations

por Dite, G S, Whittemore, A S, Knight, J A, John, E M, Milne, R L, Andrulis, I L, Southey, M C, McCredie, M R E, Giles, G G, Miron, A, Phipps, A I, West, D W, Hopper, J L
Publicado 2010

MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome

por Hassel, J C, Sucker, A, Edler, L, Kurzen, H, Moll, I, Stresemann, C, Spieth, K, Mauch, C, Rass, K, Dummer, R, Schadendorf, D
Publicado 2010