Practice effects in performance outcome measures in patients living with neurologic disorders – A systematic review

por Holm, Sven P., Wolfer, Arnaud M., Pointeau, Grégoire H.S., Lipsmeier, Florian, Lindemann, Michael
Publicado 2022

A fruit extract of Styphnolobium japonicum (L.) counteracts oxidative stress and mediates neuroprotection in Caenorhabditis elegans

por Thabit, Sara, Handoussa, Heba, ElSayed, Nesrine S., Breitinger, Hans-Georg, Breitinger, Ulrike, Wink, Michael
Publicado 2023

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

por Østergaard, Michael E., Southwell, Amber L., Kordasiewicz, Holly, Watt, Andrew T., Skotte, Niels H., Doty, Crystal N., Vaid, Kuljeet, Villanueva, Erika B., Swayze, Eric E., Frank Bennett, C., Hayden, Michael R., Seth, Punit P.
Publicado 2013

Bark Extract of the Amazonian Tree Endopleura uchi (Humiriaceae) Extends Lifespan and Enhances Stress Resistance in Caenorhabditis elegans

por Peixoto, Herbenya, Roxo, Mariana, Silva, Emerson, Valente, Karla, Braun, Markus, Wang, Xiaojuan, Wink, Michael
Publicado 2019

The Role of the Thioredoxin System in Brain Diseases

por Bjørklund, Geir, Zou, Lili, Peana, Massimiliano, Chasapis, Christos T., Hangan, Tony, Lu, Jun, Maes, Michael
Publicado 2022

Huntingtin Decreases Susceptibility to a Spontaneous Seizure Disorder in FVN/B Mice

por Van Raamsdonk, Jeremy M., Al-Shekaili, Hilal H., Wagner, Laura, Bredy, Tim W, Chan, Laura, Pearson, Jacqueline, Schwab, Claudia, Murphy, Zoe, Devon, Rebecca S., Lu, Ge, Kobor, Michael S., Hayden, Michael R., Leavitt, Blair R.
Publicado 2023

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

por Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E., Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R.
Publicado 2018

Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage

por Lemarié, Fanny L., Sanders, Shaun S., Nguyen, Yen, Martin, Dale D. O., Hayden, Michael R.
Publicado 2023

Effects of Pridopidine on Functional Capacity in Early-Stage Participants from the PRIDE-HD Study

por McGarry, Andrew, Leinonen, Mika, Kieburtz, Karl, Geva, Michal, Olanow, C. Warren, Hayden, Michael
Publicado 2020

Conformational Targeting of Fibrillar Polyglutamine Proteins in Live Cells Escalates Aggregation and Cytotoxicity

por Kvam, Erik, Nannenga, Brent L., Wang, Min S., Jia, Zongjian, Sierks, Michael R., Messer, Anne
Publicado 2009

Suppression of protein aggregation by chaperone modification of high molecular weight complexes

por Labbadia, John, Novoselov, Sergey S., Bett, John S., Weiss, Andreas, Paganetti, Paolo, Bates, Gillian P., Cheetham, Michael E.
Publicado 2012

Bcl11b—A Critical Neurodevelopmental Transcription Factor—Roles in Health and Disease

por Lennon, Matthew J., Jones, Simon P., Lovelace, Michael D., Guillemin, Gilles J., Brew, Bruce J.
Publicado 2017

Selective neuronal requirement for huntingtin in the developing zebrafish

por Henshall, Tanya L., Tucker, Ben, Lumsden, Amanda L., Nornes, Svanhild, Lardelli, Michael T., Richards, Robert I.
Publicado 2009

Ubiquitin Accumulation on Disease Associated Protein Aggregates Is Correlated with Nuclear Ubiquitin Depletion, Histone De-Ubiquitination and Impaired DNA Damage Response

por Ben Yehuda, Adi, Risheq, Marwa, Novoplansky, Ofra, Bersuker, Kirill, Kopito, Ron R., Goldberg, Michal, Brandeis, Michael
Publicado 2017

The Role of the Antioxidant Response in Mitochondrial Dysfunction in Degenerative Diseases: Cross-Talk between Antioxidant Defense, Autophagy, and Apoptosis

por Huang, Michael L.-H., Chiang, Shannon, Kalinowski, Danuta S., Bae, Dong-Hun, Sahni, Sumit, Richardson, Des R.
Publicado 2019

Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells

por Pinho, Brígida R., Reis, Sara D., Hartley, Richard C., Murphy, Michael P., Oliveira, Jorge M.A.
Publicado 2019

Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

por Meriin, Anatoli B., Zhang, Xiaoqian, He, Xiangwei, Newnam, Gary P., Chernoff, Yury O., Sherman, Michael Y.
Publicado 2002

A Fully-Automated Subcortical and Ventricular Shape Generation Pipeline Preserving Smoothness and Anatomical Topology

por Tang, Xiaoying, Luo, Yuan, Chen, Zhibin, Huang, Nianwei, Johnson, Hans J., Paulsen, Jane S., Miller, Michael I.
Publicado 2018

Pridopidine Induces Functional Neurorestoration Via the Sigma-1 Receptor in a Mouse Model of Parkinson’s Disease

por Francardo, Veronica, Geva, Michal, Bez, Francesco, Denis, Quentin, Steiner, Lilach, Hayden, Michael R., Cenci, M. Angela
Publicado 2019

Extensive Expression Analysis of Htt Transcripts in Brain Regions from the zQ175 HD Mouse Model Using a QuantiGene Multiplex Assay

por Papadopoulou, Aikaterini S., Gomez-Paredes, Casandra, Mason, Michael A., Taxy, Bridget A., Howland, David, Bates, Gillian P.
Publicado 2019