Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice

por Sanders, Shaun S., Parsons, Matthew P., Mui, Katherine K. N., Southwell, Amber L., Franciosi, Sonia, Cheung, Daphne, Waltl, Sabine, Raymond, Lynn A., Hayden, Michael R.
Publicado 2016

Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis

por Lovelace, Michael D., Varney, Bianca, Sundaram, Gayathri, Franco, Nunzio F., Ng, Mei Li, Pai, Saparna, Lim, Chai K., Guillemin, Gilles J., Brew, Bruce J.
Publicado 2016

Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020

por Kimball, Anne, Hatfield, Kelly M., Arons, Melissa, James, Allison, Taylor, Joanne, Spicer, Kevin, Bardossy, Ana C., Oakley, Lisa P., Tanwar, Sukarma, Chisty, Zeshan, Bell, Jeneita M., Methner, Mark, Harney, Josh, Jacobs, Jesica R., Carlson, Christina M., McLaughlin, Heather P., Stone, Nimalie, Clark, Shauna, Brostrom-Smith, Claire, Page, Libby C., Kay, Meagan, Lewis, James, Russell, Denny, Hiatt, Brian, Gant, Jessica, Duchin, Jeffrey S., Clark, Thomas A., Honein, Margaret A., Reddy, Sujan C., Jernigan, John A., Baer, Atar, Barnard, Leslie M., Benoliel, Eileen, Fagalde, Meaghan S., Ferro, Jessica, Smith, Hal Garcia, Gonzales, Elysia, Hatley, Noel, Hatt, Grace, Hope, Michaela, Huntington-Frazier, Melinda, Kawakami, Vance, Lenahan, Jennifer L., Lukoff, Margaret D., Maier, Emily B., McKeirnan, Shelly, Montgomery, Patricia, Morgan, Jennifer L., Mummert, Laura A., Pogosjans, Sargis, Riedo, Francis X., Schwarcz, Leilani, Smith, Daniel, Stearns, Steve, Sykes, Kaitlyn J., Whitney, Holly, Ali, Hammad, Banks, Michelle, Balajee, Arun, Chow, Eric J., Cooper, Barbara, Currie, Dustin W., Dyal, Jonathan, Healy, Jessica, Hughes, Michael, McMichael, Temet M., Nolen, Leisha, Olson, Christine, Rao, Agam K., Schmit, Kristine, Schwartz, Noah G., Tobolowsky, Farrell, Zacks, Rachael, Zane, Suzanne
Publicado 2020

Restriction endonuclease TseI cleaves A:A and T:T mismatches in CAG and CTG repeats

por Ma, Long, Chen, Kai, Clarke, David J., Nortcliffe, Christopher P., Wilson, Geoffrey G., Edwardson, J. Michael, Morton, A. Jennifer, Jones, Anita C., Dryden, David T. F.
Publicado 2013

Neurodegenerative Disease and the NLRP3 Inflammasome

por Holbrook, Jonathan A., Jarosz-Griffiths, Heledd H., Caseley, Emily, Lara-Reyna, Samuel, Poulter, James A., Williams-Gray, Caroline H., Peckham, Daniel, McDermott, Michael F.
Publicado 2021

Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies

por Huang, Yinrou, Zhao, Mengke, Chen, Xuemei, Zhang, Ruoyu, Le, Anh, Hong, Michael, Zhang, Yufei, Jia, Lin, Zang, Weidong, Jiang, Chao, Wang, Junmin, Fan, Xiaochong, Wang, Jian
Publicado 2023

Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum

por Grondin, Richard, Kaytor, Michael D., Ai, Yi, Nelson, Peter T., Thakker, Deepak R., Heisel, Jennifer, Weatherspoon, Marcy R., Blum, Janelle L., Burright, Eric N., Zhang, Zhiming, Kaemmerer, William F.
Publicado 2012

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

por Aron Badin, Romina, Bugi, Aurore, Williams, Susannah, Vadori, Marta, Michael, Marie, Jan, Caroline, Nassi, Alberto, Lecourtois, Sophie, Blancher, Antoine, Cozzi, Emanuele, Hantraye, Philippe, Perrier, Anselme L.
Publicado 2019

Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases

por Benatar, Michael, Wuu, Joanne, McHutchison, Caroline, Postuma, Ronald B, Boeve, Bradley F, Petersen, Ronald, Ross, Christopher A, Rosen, Howard, Arias, Jalayne J, Fradette, Stephanie, McDermott, Michael P, Shefner, Jeremy, Stanislaw, Christine, Abrahams, Sharon, Cosentino, Stephanie, Andersen, Peter M, Finkel, Richard S, Granit, Volkan, Grignon, Anne-Laure, Rohrer, Jonathan D, McMillan, Corey T, Grossman, Murray, Al-Chalabi, Ammar, Turner, Martin R
Publicado 2021

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy

por Deneubourg, Celine, Ramm, Mauricio, Smith, Luke J., Baron, Olga, Singh, Kritarth, Byrne, Susan C., Duchen, Michael R., Gautel, Mathias, Eskelinen, Eeva-Liisa, Fanto, Manolis, Jungbluth, Heinz
Publicado 2021

Low Levels of Human HIP14 Are Sufficient to Rescue Neuropathological, Behavioural, and Enzymatic Defects Due to Loss of Murine HIP14 in Hip14−/− Mice

por Young, Fiona B., Franciosi, Sonia, Spreeuw, Amanda, Deng, Yu, Sanders, Shaun, Tam, Natalie C. M., Huang, Kun, Singaraja, Roshni R., Zhang, Weining, Bissada, Nagat, Kay, Chris, Hayden, Michael R.
Publicado 2012

COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020

por McMichael, Temet M., Clark, Shauna, Pogosjans, Sargis, Kay, Meagan, Lewis, James, Baer, Atar, Kawakami, Vance, Lukoff, Margaret D., Ferro, Jessica, Brostrom-Smith, Claire, Riedo, Francis X., Russell, Denny, Hiatt, Brian, Montgomery, Patricia, Rao, Agam K., Currie, Dustin W., Chow, Eric J., Tobolowsky, Farrell, Bardossy, Ana C., Oakley, Lisa P., Jacobs, Jesica R., Schwartz, Noah G., Stone, Nimalie, Reddy, Sujan C., Jernigan, John A., Honein, Margaret A., Clark, Thomas A., Duchin, Jeffrey S., Fagalde, Meaghan S., Lenahan, Jennifer L., Maier, Emily B., Sykes, Kaitlyn J., Hatt, Grace, Whitney, Holly, Huntington-Frazier, Melinda, Gonzales, Elysia, Mummert, Laura A., Smith, Hal Garcia, Stearns, Steve, Benoliel, Eileen, McKeirnan, Shelly, Morgan, Jennifer L., Smith, Daniel, Hope, Michaela, Hatley, Noel, Barnard, Leslie M., Schwarcz, Leilani, Yarid, Nicole, Yim, Eric, Kreider, Sandra, Barr, Dawn, Wilde, Nancy, Dorman, Courtney, Lam, Airin, Harris, Jeanette, Bruce, Hollianne, Spitters, Christopher, District, Snohomish Health, Zacks, Rachael, Dyal, Jonathan, Hughes, Michael, Carlson, Christina, Cooper, Barbara, Banks, Michelle, McLaughlin, Heather, Balajee, Arun, Olson, Christine, Zane, Suzanne, Ali, Hammad, Healy, Jessica, Schmit, Kristine, Spicer, Kevin, Chisty, Zeshan, Tanwar, Sukarma, Taylor, Joanne, Nolen, Leisha, Bell, Jeneita, Hatfield, Kelly, Arons, Melissa, Kimball, Anne, James, Allison, Methner, Mark, Harney, Joshua
Publicado 2020

Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models

por Joachimiak, Paweł, Ciesiołka, Adam, Kozłowska, Emilia, Świtoński, Paweł M., Figura, Grzegorz, Ciołak, Agata, Adamek, Grażyna, Surdyka, Magdalena, Kalinowska-Pośka, Żaneta, Figiel, Maciej, Caron, Nicholas S., Hayden, Michael R., Fiszer, Agnieszka
Publicado 2023

Cellular manganese content is developmentally regulated in human dopaminergic neurons

por Kumar, Kevin K., Lowe, Jr., Edward W., Aboud, Asad A., Neely, M. Diana, Redha, Rey, Bauer, Joshua A., Odak, Mihir, Weaver, C. David, Meiler, Jens, Aschner, Michael, Bowman, Aaron B.
Publicado 2014

Mitochondrial dysfunction in neurological disorders: Exploring mitochondrial transplantation

por Norat, Pedro, Soldozy, Sauson, Sokolowski, Jennifer D., Gorick, Catherine M., Kumar, Jeyan S., Chae, Youngrok, Yağmurlu, Kaan, Prada, Francesco, Walker, Melanie, Levitt, Michael R., Price, Richard J., Tvrdik, Petr, Kalani, M. Yashar S.
Publicado 2020

NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport

por Yang, Sen, Niou, Zhen-Xian, Enriquez, Andrea, LaMar, Jacob, Huang, Jui-Yen, Ling, Karen, Jafar-Nejad, Paymaan, Gilley, Jonathan, Coleman, Michael P., Tennessen, Jason M., Rangaraju, Vidhya, Lu, Hui-Chen
Publicado 2023

Outcomes of COVID-19 in patients with CLL: a multicenter international experience

por Mato, Anthony R., Roeker, Lindsey E., Lamanna, Nicole, Allan, John N., Leslie, Lori, Pagel, John M., Patel, Krish, Osterborg, Anders, Wojenski, Daniel, Kamdar, Manali, Huntington, Scott F., Davids, Matthew S., Brown, Jennifer R., Antic, Darko, Jacobs, Ryan, Ahn, Inhye E., Pu, Jeffrey, Isaac, Krista M., Barr, Paul M., Ujjani, Chaitra S., Geyer, Mark B., Berman, Ellin, Zelenetz, Andrew D., Malakhov, Nikita, Furman, Richard R., Koropsak, Michael, Bailey, Neil, Hanson, Lotta, Perini, Guilherme F., Ma, Shuo, Ryan, Christine E., Wiestner, Adrian, Portell, Craig A., Shadman, Mazyar, Chong, Elise A., Brander, Danielle M., Sundaram, Suchitra, Seddon, Amanda N., Seymour, Erlene, Patel, Meera, Martinez-Calle, Nicolas, Munir, Talha, Walewska, Renata, Broom, Angus, Walter, Harriet, El-Sharkawi, Dima, Parry, Helen, Wilson, Matthew R., Patten, Piers E.M., Hernández-Rivas, José-Ángel, Miras, Fatima, Fernández Escalada, Noemi, Ghione, Paola, Nabhan, Chadi, Lebowitz, Sonia, Bhavsar, Erica, López-Jiménez, Javier, Naya, Daniel, Garcia-Marco, Jose Antonio, Skånland, Sigrid S., Cordoba, Raul, Eyre, Toby A.
Publicado 2020

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription

por Yang, Lichuan, Calingasan, Noel Y., Thomas, Bobby, Chaturvedi, Rajnish K., Kiaei, Mahmoud, Wille, Elizabeth J., Liby, Karen T., Williams, Charlotte, Royce, Darlene, Risingsong, Renee, Musiek, Eric S., Morrow, Jason D., Sporn, Michael, Beal, M. Flint
Publicado 2009

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease

por Underwood, Benjamin R., Imarisio, Sara, Fleming, Angeleen, Rose, Claudia, Krishna, Gauri, Heard, Phoebe, Quick, Marie, Korolchuk, Viktor I., Renna, Maurizio, Sarkar, Sovan, García-Arencibia, Moisés, O'Kane, Cahir J., Murphy, Michael P., Rubinsztein, David C.
Publicado 2010

Dysfunction of ventrolateral striatal dopamine receptor type 2-expressing medium spiny neurons impairs instrumental motivation

por Tsutsui-Kimura, Iku, Takiue, Hiroyuki, Yoshida, Keitaro, Xu, Ming, Yano, Ryutaro, Ohta, Hiroyuki, Nishida, Hiroshi, Bouchekioua, Youcef, Okano, Hideyuki, Uchigashima, Motokazu, Watanabe, Masahiko, Takata, Norio, Drew, Michael R., Sano, Hiromi, Mimura, Masaru, Tanaka, Kenji F.
Publicado 2017