Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System

por An, Mahru C., O'Brien, Robert N., Zhang, Ningzhe, Patra, Biranchi N., De La Cruz, Michael, Ray, Animesh, Ellerby, Lisa M.
Publicado 2014

Indirect inhibition of 26S proteasome activity in a cellular model of Huntington’s disease

por Hipp, Mark S., Patel, Chetan N., Bersuker, Kirill, Riley, Brigit E., Kaiser, Stephen E., Shaler, Thomas A., Brandeis, Michael, Kopito, Ron R.
Publicado 2012

Quantitative Electroencephalographic Biomarkers in Preclinical and Human Studies of Huntington’s Disease: Are They Fit-for-Purpose for Treatment Development?

por Leuchter, Michael K., Donzis, Elissa J., Cepeda, Carlos, Hunter, Aimee M., Estrada-Sánchez, Ana María, Cook, Ian A., Levine, Michael S., Leuchter, Andrew F.
Publicado 2017

Progressive alterations in white matter microstructure across the timecourse of Huntington's disease

por Estevez‐Fraga, Carlos, Elmalem, Michael S., Papoutsi, Marina, Durr, Alexandra, Rees, Elin M., Hobbs, Nicola Z., Roos, Raymund A. C., Landwehrmeyer, Bernhard, Leavitt, Blair R., Langbehn, Douglas R., Scahill, Rachael I., Rees, Geraint, Tabrizi, Sarah J., Gregory, Sarah
Publicado 2023

Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records

por Evans, Stephen JW, Douglas, Ian, Rawlins, Michael D, Wexler, Nancy S, Tabrizi, Sarah J, Smeeth, Liam
Publicado 2013

A genetic modifier suggests that endurance exercise exacerbates Huntington's disease

por Corrochano, Silvia, Blanco, Gonzalo, Williams, Debbie, Wettstein, Jessica, Simon, Michelle, Kumar, Saumya, Moir, Lee, Agnew, Thomas, Stewart, Michelle, Landman, Allison, Kotiadis, Vassilios N, Duchen, Michael R, Wackerhage, Henning, Rubinsztein, David C, Brown, Steve D M, Acevedo-Arozena, Abraham
Publicado 2018

Genotyping single nucleotide polymorphisms for allele-selective therapy in Huntington disease

por Claassen, Daniel O., Corey-Bloom, Jody, Dorsey, E. Ray, Edmondson, Mary, Kostyk, Sandra K., LeDoux, Mark S., Reilmann, Ralf, Rosas, H. Diana, Walker, Francis, Wheelock, Vicki, Svrzikapa, Nenad, Longo, Kenneth A., Goyal, Jaya, Hung, Serena, Panzara, Michael A.
Publicado 2020

Correlation between Relaxometry and Diffusion Tensor Imaging in the Globus Pallidus of Huntington’s Disease Patients

por Syka, Michael, Keller, Jiří, Klempíř, Jiří, Rulseh, Aaron M., Roth, Jan, Jech, Robert, Vorisek, Ivan, Vymazal, Josef
Publicado 2015

Dysarthria Subgroups in Talkers with Huntington’s Disease: Comparison of Two Data-Driven Classification Approaches

por Kim, Daniel, Diehl, Sarah, de Riesthal, Michael, Tjaden, Kris, Wilson, Stephen M., Claassen, Daniel O., Mefferd, Antje S.
Publicado 2022

Intraparenchymal Striatal Transplants Required for Maintenance of Behavioral Recovery in an Animal Model of Huntington's Disease

por Sanberg, Paul R., Giòrdano, Magda, Henault, Mark A., Nash, David R., Ragozzino, Michael E., Hagenmeyer-Houser, Starr H.
Publicado 1989

Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington’s Disease

por Dasgupta, Sayani, Fishman, Michael A., Mahallati, Hana, Castro, Leandro M., Tashima, Alexandre K., Ferro, Emer S., Fricker, Lloyd D.
Publicado 2015

Linking white matter and deep gray matter alterations in premanifest Huntington disease

por Faria, Andreia V., Ratnanather, J. Tilak, Tward, Daniel J., Lee, David Soobin, van den Noort, Frieda, Wu, Dan, Brown, Timothy, Johnson, Hans, Paulsen, Jane S., Ross, Christopher A., Younes, Laurent, Miller, Michael I.
Publicado 2016

Using Actiwatch to monitor circadian rhythm disturbance in Huntington’ disease: A cautionary note

por Townhill, Jenny, Hughes, Alis C., Thomas, Benny, Busse, Monica E., Price, Kathy, Dunnett, Stephen B., Hastings, Michael H., Rosser, Anne E.
Publicado 2016

Juvenile Huntington's disease: a population-based study using the General Practice Research Database

por Douglas, Ian, Evans, Stephen, Rawlins, Michael D, Smeeth, Liam, Tabrizi, Sarah J, Wexler, Nancy S
Publicado 2013

IKKβ slows Huntington’s disease progression in R6/1 mice

por Ochaba, Joseph, Fote, Gianna, Kachemov, Marketta, Thein, Soe, Yeung, Sylvia Y., Lau, Alice L., Hernandez, Sarah, Lim, Ryan G., Casale, Malcolm, Neel, Michael J., Monuki, Edwin S., Reidling, Jack, Housman, David E., Thompson, Leslie M., Steffan, Joan S.
Publicado 2019

Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in Huntington’s disease models

por Mason, Michael A., Gomez-Paredes, Casandra, Sathasivam, Kirupa, Neueder, Andreas, Papadopoulou, Aikaterini-Smaragdi, Bates, Gillian P.
Publicado 2020

FAN1 modifies Huntington’s disease progression by stabilizing the expanded HTT CAG repeat

por Goold, Robert, Flower, Michael, Moss, Davina Hensman, Medway, Chris, Wood-Kaczmar, Alison, Andre, Ralph, Farshim, Pamela, Bates, Gill P, Holmans, Peter, Jones, Lesley, Tabrizi, Sarah J
Publicado 2019

Cholesterol‐loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

por Valenza, Marta, Chen, Jane Y, Di Paolo, Eleonora, Ruozi, Barbara, Belletti, Daniela, Ferrari Bardile, Costanza, Leoni, Valerio, Caccia, Claudio, Brilli, Elisa, Di Donato, Stefano, Boido, Marina M, Vercelli, Alessandro, Vandelli, Maria A, Forni, Flavio, Cepeda, Carlos, Levine, Michael S, Tosi, Giovanni, Cattaneo, Elena
Publicado 2015

Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease

por Wright, Galen E B, Caron, Nicholas S, Ng, Bernard, Casal, Lorenzo, Casazza, William, Xu, Xiaohong, Ooi, Jolene, Pouladi, Mahmoud A, Mostafavi, Sara, Ross, Colin J D, Hayden, Michael R
Publicado 2020

Longitudinal imaging highlights preferential basal ganglia circuit atrophy in Huntington’s disease

por Liu, Chin-Fu, Younes, Laurent, Tong, Xiao J, Hinkle, Jared T, Wang, Maggie, Phatak, Sanika, Xu, Xin, Bu, Xuan, Looi, Vivian, Bang, Jee, Tabrizi, Sarah J, Scahill, Rachael I, Paulsen, Jane S, Georgiou-Karistianis, Nellie, Faria, Andreia V, Miller, Michael I, Ratnanather, J Tilak, Ross, Christopher A
Publicado 2023