Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

por Benraiss, Abdellatif, Wang, Su, Herrlinger, Stephanie, Li, Xiaojie, Chandler-Militello, Devin, Mauceri, Joseph, Burm, Hayley B., Toner, Michael, Osipovitch, Mikhail, Jim Xu, Qiwu, Ding, Fengfei, Wang, Fushun, Kang, Ning, Kang, Jian, Curtin, Paul C., Brunner, Daniela, Windrem, Martha S., Munoz-Sanjuan, Ignacio, Nedergaard, Maiken, Goldman, Steven A.
Publicado 2016

Disease-Toxicant Interactions in Manganese Exposed Huntington Disease Mice: Early Changes in Striatal Neuron Morphology and Dopamine Metabolism

por Madison, Jennifer L., Wegrzynowicz, Michal, Aschner, Michael, Bowman, Aaron B.
Publicado 2012

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

por Siebzehnrübl, Florian A., Raber, Kerstin A., Urbach, Yvonne K., Schulze-Krebs, Anja, Canneva, Fabio, Moceri, Sandra, Habermeyer, Johanna, Achoui, Dalila, Gupta, Bhavana, Steindler, Dennis A., Stephan, Michael, Nguyen, Huu Phuc, Bonin, Michael, Riess, Olaf, Bauer, Andreas, Aigner, Ludwig, Couillard-Despres, Sebastien, Paucar, Martin Arce, Svenningsson, Per, Osmand, Alexander, Andreew, Alexander, Zabel, Claus, Weiss, Andreas, Kuhn, Rainer, Moussaoui, Saliha, Blockx, Ines, Van der Linden, Annemie, Cheong, Rachel Y., Roybon, Laurent, Petersén, Åsa, von Hörsten, Stephan
Publicado 2018

Somatostatin Receptor 1 and 5 Double Knockout Mice Mimic Neurochemical Changes of Huntington's Disease Transgenic Mice

por Rajput, Padmesh S., Kharmate, Geetanjali, Norman, Michael, Liu, Shi-He, Sastry, Bhagavatula R., Brunicardi, Charles F., Kumar, Ujendra
Publicado 2011

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

por Kovalenko, Marina, Erdin, Serkan, Andrew, Marissa A, St Claire, Jason, Shaughnessey, Melissa, Hubert, Leroy, Neto, João Luís, Stortchevoi, Alexei, Fass, Daniel M, Mouro Pinto, Ricardo, Haggarty, Stephen J, Wilson, John H, Talkowski, Michael E, Wheeler, Vanessa C
Publicado 2020

Major Contribution of Somatostatin-Expressing Interneurons and Cannabinoid Receptors to Increased GABA Synaptic Activity in the Striatum of Huntington’s Disease Mice

por Holley, Sandra M., Galvan, Laurie, Kamdjou, Talia, Dong, Ashley, Levine, Michael S., Cepeda, Carlos
Publicado 2019

Silencing of the Mutant Huntingtin Gene through CRISPR-Cas9 Improves the Mitochondrial Biomarkers in an In Vitro Model of Huntington’s Disease

por Dunbar, Gary L., Koneru, Sindhuja, Kolli, Nivya, Sandstrom, Michael, Maiti, Panchanan, Rossignol, Julien
Publicado 2019

Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model

por Kang, Rujun, Wang, Liang, Sanders, Shaun S., Zuo, Kurt, Hayden, Michael R., Raymond, Lynn A.
Publicado 2019

Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review

por Wexler, Nancy S, Collett, Laura, Wexler, Alice R, Rawlins, Michael D, Tabrizi, Sarah J, Douglas, Ian, Smeeth, Liam, Evans, Stephen J
Publicado 2016

A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

por Todd, Daniel, Gowers, Ian, Dowler, Simon J., Wall, Michael D., McAllister, George, Fischer, David F., Dijkstra, Sipke, Fratantoni, Silvina A., van de Bospoort, Rhea, Veenman-Koepke, Jessica, Flynn, Geraldine, Arjomand, Jamshid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Wityak, John, Bard, Jonathan A.
Publicado 2014

Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range

por Findlay Black, Hailey, Wright, Galen E. B., Collins, Jennifer A., Caron, Nicholas, Kay, Chris, Xia, Qingwen, Arning, Larissa, Bijlsma, Emilia K., Squitieri, Ferdinando, Nguyen, Huu Phuc, Hayden, Michael R.
Publicado 2020

Establishing normative data for the evaluation of cognitive performance in Huntington’s disease considering the impact of gender, age, language, and education

por Mühlbäck, Alžbeta, Mana, Josef, Wallner, Michael, Frank, Wiebke, Lindenberg, Katrin S., Hoffmann, Rainer, Klempířová, Olga, Klempíř, Jiří, Landwehrmeyer, G. Bernhard, Bezdicek, Ondrej
Publicado 2023

Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington’s disease: a 12-month longitudinal study

por Toh, Eng A, MacAskill, Michael R, Dalrymple-Alford, John C, Myall, Daniel J, Livingston, Leslie, Macleod, Sandy AD, Anderson, Tim J
Publicado 2014

Impact of the control for corrupted diffusion tensor imaging data in comparisons at the group level: an application in Huntington disease

por Müller, Hans-Peter, Kassubek, Jan, Grön, Georg, Sprengelmeyer, Reiner, Ludolph, Albert C, Klöppel, Stefan, Hobbs, Nicola Z, Roos, Raymund AC, Duerr, Alexandra, Tabrizi, Sarah J, Orth, Michael, Süssmuth, Sigurd D, Landwehrmeyer, G Bernhard
Publicado 2014

Reduction in Subventricular Zone-Derived Olfactory Bulb Neurogenesis in a Rat Model of Huntington’s Disease Is Accompanied by Striatal Invasion of Neuroblasts

por Kandasamy, Mahesh, Rosskopf, Michael, Wagner, Katrin, Klein, Barbara, Couillard-Despres, Sebastien, Reitsamer, Herbert A., Stephan, Michael, Nguyen, Huu Phuc, Riess, Olaf, Bogdahn, Ulrich, Winkler, Jürgen, von Hörsten, Stephan, Aigner, Ludwig
Publicado 2015

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

por Björkqvist, Maria, Wild, Edward J., Thiele, Jenny, Silvestroni, Aurelio, Andre, Ralph, Lahiri, Nayana, Raibon, Elsa, Lee, Richard V., Benn, Caroline L., Soulet, Denis, Magnusson, Anna, Woodman, Ben, Landles, Christian, Pouladi, Mahmoud A., Hayden, Michael R., Khalili-Shirazi, Azadeh, Lowdell, Mark W., Brundin, Patrik, Bates, Gillian P., Leavitt, Blair R., Möller, Thomas, Tabrizi, Sarah J.
Publicado 2008

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease

por Schmidt, Mandi E., Buren, Caodu, Mackay, James P., Cheung, Daphne, Dal Cengio, Louisa, Raymond, Lynn A., Hayden, Michael R.
Publicado 2018

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

por Pinho, Brígida R., Duarte, Ana I., Canas, Paula M., Moreira, Paula I., Murphy, Michael P., Oliveira, Jorge M.A.
Publicado 2020

Genomic Instability Associated with p53 Knockdown in the Generation of Huntington’s Disease Human Induced Pluripotent Stem Cells

por Tidball, Andrew M., Neely, M. Diana, Chamberlin, Reed, Aboud, Asad A., Kumar, Kevin K., Han, Bingying, Bryan, Miles R., Aschner, Michael, Ess, Kevin C., Bowman, Aaron B.
Publicado 2016

Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease

por Vittori, Angelica, Breda, Carlo, Repici, Mariaelena, Orth, Michael, Roos, Raymund A.C., Outeiro, Tiago F., Giorgini, Flaviano, Hollox, Edward J.
Publicado 2014