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  1. 41
    “…MAIN METHODS: Tissues were collected in the middle of murine rest and active phases, at noon and midnight, respectively. ET-1, ET(A) and ET(B) mRNA expressions were measured in the lung, heart, liver, renal inner medulla and renal cortex of wild type and Per1 heterozygous mice using real-time quantitative RT-PCR. …”
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    Tissue-specific and time-dependent regulation of the endothelin axis by the circadian clock protein Per1
  2. 42
    “…Furthermore, Ap expression in l-LNvs showed daily rhythms (peaking at midnight), which are generated by a direct light-dependent mechanism rather than by the endogenous clock. …”
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    Modulation of light-driven arousal by LIM-homeodomain transcription factor Apterous in large PDF-positive lateral neurons of the Drosophila brain
  3. 43
    “…In contrast, Beclin1 revealed a 24-h cycle with the highest level observed at midnight. Atg7 was also on a 24-h cycle with peak expression at 8:15 am, coinciding with the first peak expression of Atg9 and LC3. …”
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    Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina
  4. 44
    “…Four modules were identified from the gene coexpression network, one of which was found to be significantly associated with patient survival time. The expression status of 28 genes formed the black module (basal); 18 genes, dark red module (claudin-low); nine genes, brown module (luminal), and seven genes, midnight blue module (nonmalignant). …”
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    Identification of Prognostic Candidate Genes in Breast Cancer by Integrated Bioinformatic Analysis
  5. 45
    “…Finally, we found a rhythmic oscillation of goat mRNA expression in the hypothalamus, pituitary and intestinal bulb of goldfish fed at midday, but not at midnight. …”
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    Characterization of Ghrelin O-Acyltransferase (GOAT) in goldfish (Carassius auratus)
  6. 46
    “…We detail the quality assessment of the datasets and the complete annotation procedure, providing the possibility to investigate daily gene expression of this ecologically important species at high Arctic latitudes, and to compare gene expression according to latitude and sea ice-coverage.…”
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    Daily transcriptomes of the copepod Calanus finmarchicus during the summer solstice at high Arctic latitudes
  7. 47
    “…By applying WGCNA, we identified twenty-two differential expression modules, and the midnight blue module showed a strong positive correlation with drought resistance characteristics. …”
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    Transcriptome-Based WGCNA Analysis Reveals the Mechanism of Drought Resistance Differences in Sweetpotato (Ipomoea batatas (L.) Lam.)
  8. 48
    “…These findings are hypothesized to be the result of a change in the sensitivity of the melanopsin-expressing retinal ganglion cells to light during the night.…”
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    Preliminary evidence for a change in spectral sensitivity of the circadian system at night
  9. 49
    “…MATERIAL/METHODS: We randomly divided 981 healthy Chinese men into groups according to research-set bedtimes (A=8–10 PM, B=after 10 PM, and C=after midnight) and sleep durations: group 1=<6.0 h (short), group 2=7.0–8.0 h (average), and group 3=>9.0 h (long). …”
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    Sleep Deprivation and Late Bedtime Impair Sperm Health Through Increasing Antisperm Antibody Production: A Prospective Study of 981 Healthy Men
  10. 50
    “…At TMHD, patients had significantly higher TAC levels at midday than midnight (12:00: 0.83±0.10 vs. 00:00: 0.74±0.12, p<0.006) as it has been reported in healthy subjects. …”
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    A three-month longitudinal study of changes in day/night serum total antioxidant capacity in paranoid schizophrenia
  11. 51
    “…Over a 24-h in-hospital period, plasma aldosterone levels taken at midnight, 0400, 0800, 1200, 1600, and 2000 h were measured. …”
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    The Association between a 24-Hour Blood Pressure Pattern and Circadian Change in Plasma Aldosterone Concentration for Patients with Aldosterone-Producing Adenoma
  12. 52
    “…We found a series of glyphosate, s-Metolachlor, fenclorim, metcamifen and GA3 response genes were expressed following stable circadian rhythms. In order to determine the patterns of their temporal expression, co-expression network analysis was done on 10,467 genes that were periodically expressed throughout a 24-hour period. …”
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    Multi-omics analyses reveal the crosstalk between the circadian clock and the response to herbicide application in Oryza sativa
  13. 53
    “…Key behaviours, physiologies and gene expressions in Anopheles mosquitoes impact the transmission of Plasmodium. …”
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    The circadian clock modulates Anopheles gambiae infection with Plasmodium falciparum
  14. 54
    “…Collectively, photocycles and thermocycles regulated about 60% of the expressed nuclear genes in rice and poplar. Depending on the condition tested, up to one third of oscillating Arabidopsis-poplar-rice orthologs were phased within three hours of each other suggesting a high degree of conservation in terms of rhythmic gene expression. …”
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    Global Profiling of Rice and Poplar Transcriptomes Highlights Key Conserved Circadian-Controlled Pathways and cis-Regulatory Modules
  15. 55
    “…We therefore compared behavioural, transcriptional and metabolomic responses of captive great tits (Parus major) to three ALAN intensities or to dark nights, recording activity and sampling brain, liver, spleen and blood at mid-day and midnight. ALAN advanced wake-up time, and this shift was paralleled by advanced expression of the clock gene BMAL1 in all tissues, suggesting close links between behaviour and clock gene expression across tissues. …”
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    Integrated molecular and behavioural data reveal deep circadian disruption in response to artificial light at night in male Great tits (Parus major)
  16. 56
    “…Methods: Weighted gene co-expression network analysis (WGCNA) was used to analyze the expression profiles of the cancer cell line from GDSC2 to identify 5-FU-related modules and hub genes. …”
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    Heterogeneity characterization of hepatocellular carcinoma based on the sensitivity to 5-fluorouracil and development of a prognostic regression model
  17. 57
    “…Tissue samples were used for mRNA expression analysis of drug-metabolizing enzymes. In patients, a cross-over study was performed. …”
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    Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients
  18. 58
    por Hamid, Sana
    Publicado 2014
    “…A dramatically reduced 25% expressed subjective dehydration and 25% showed clinical evidence of dehydration. …”
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    Pre-operative fasting - a patient centered approach
  19. 59
    “…RESULTS: Through bioinformatics analysis, patients diagnosed with osteosarcoma were classified into one of 4 subtypes (quiescent, glycolysis, cholesterol, and mixed subtypes), which differed significantly in terms of prognosis and tumor microenvironment. Weighted gene co-expression network analysis revealed that the modules strongly correlated with glycolysis and cholesterol synthesis were the midnight blue and the yellow modules, respectively. …”
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    Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma
  20. 60
    “…Only 2.58% of minors expressed high concern about COVID-19. CONCLUSION: Lockdown due to COVID-19 has involved a global impact on minors. …”
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    Confinamiento y salud mental: análisis del impacto en una muestra de 194 pacientes de psiquiatría del niño y del adolescente
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