Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice

por Robarts, Dakota R., McGreal, Steven R., Umbaugh, David S., Parkes, Wendena S., Kotulkar, Manasi, Abernathy, Sarah, Lee, Norman, Jaeschke, Hartmut, Gunewardena, Sumedha, Whelan, Stephen A., Hanover, John A., Zachara, Natasha E., Slawson, Chad, Apte, Udayan
Publicado 2022

The Essential Role of O-GlcNAcylation in Hepatic Differentiation

por Robarts, Dakota R., Kotulkar, Manasi, Paine-Cabrera, Diego, Venneman, Kaitlyn K., Hanover, John A., Zachara, Natasha E., Slawson, Chad, Apte, Udayan
Publicado 2023

Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy

por Papanicolaou, Kyriakos N., Jung, Jessica, Ashok, Deepthi, Zhang, Wenxi, Modaressanavi, Amir, Avila, Eddie, Foster, D. Brian, Zachara, Natasha E., O'Rourke, Brian
Publicado 2023

Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function

por Gonzalez-Rellan, Maria J., Parracho, Tamara, Heras, Violeta, Rodriguez, Amaia, Fondevila, Marcos F., Novoa, Eva, Lima, Natalia, Varela-Rey, Marta, Senra, Ana, Chantada-Vazquez, Maria D.P., Ameneiro, Cristina, Bernardo, Ganeko, Fernandez-Ramos, David, Lopitz-Otsoa, Fernando, Bilbao, Jon, Guallar, Diana, Fidalgo, Miguel, Bravo, Susana, Dieguez, Carlos, Martinez-Chantar, Maria L., Millet, Oscar, Mato, Jose M., Schwaninger, Markus, Prevot, Vincent, Crespo, Javier, Frühbeck, Gema, Iruzubieta, Paula, Nogueiras, Ruben
Publicado 2023

Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex

por Lu, Ping, Liu, Yusong, He, Maozhou, Cao, Ting, Yang, Mengquan, Qi, Shutao, Yu, Hongtao, Gao, Haishan
Publicado 2023

O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development

por Webster, Danielle M, Teo, Chin Fen, Sun, Yuhua, Wloga, Dorota, Gay, Steven, Klonowski, Kimberly D, Wells, Lance, Dougan, Scott T
Publicado 2009

O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

por Guinez, Céline, Filhoulaud, Gaëlle, Rayah-Benhamed, Fadila, Marmier, Solenne, Dubuquoy, Céline, Dentin, Renaud, Moldes, Marthe, Burnol, Anne-Françoise, Yang, Xiaoyong, Lefebvre, Tony, Girard, Jean, Postic, Catherine
Publicado 2011

O-linked N-acetylglucosamine glycosylation of p65 aggravated the inflammation in both fibroblast-like synoviocytes stimulated by tumor necrosis factor-α and mice with collagen indu...

por Kim, Han Byeol, Lee, Sang Won, Mun, Chin Hee, Yoon, Ji Young, Pai, Jaeyoung, Shin, Injae, Park, Yong Beom, Lee, Soo Kon, Cho, Jin Won
Publicado 2015

O-GlcNacylation Links TxNIP to Inflammasome Activation in Pancreatic β Cells

por Filhoulaud, Gaelle, Benhamed, Fadila, Pagesy, Patrick, Bonner, Caroline, Fardini, Yann, Ilias, Anissa, Movassat, Jamileh, Burnol, Anne-Françoise, Guilmeau, Sandra, Kerr-Conte, Julie, Pattou, François, Issad, Tarik, Postic, Catherine
Publicado 2019

Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells

por Jin, Lu, Yuan, Feng, Dai, Guangcheng, Yao, Qiu, Xiang, Han, Wang, Lixia, Xue, Boxin, Shan, Yuxi, Liu, Xiaolong
Publicado 2020

O-GlcNAcylation and its role in the immune system

por Chang, Yi-Hsuan, Weng, Chia-Lin, Lin, Kuo-I
Publicado 2020

Evidence and manipulation of O-GlcNAcylation in granulosa cells of bovine antral follicles

por Maucieri, Abigail M, Townson, David H
Publicado 2021

O-GlcNAcylation contributes to intermittent hypoxia-associated vascular dysfunction via modulation of MAPKs but not CaMKII pathways

por Guo, Xueling, Deng, Yan, Zhan, Linghui, Shang, Jin, Liu, Huiguo
Publicado 2021

Pleiotropic actions of IP6K1 mediate hepatic metabolic dysfunction to promote nonalcoholic fatty liver disease and steatohepatitis

por Mukherjee, Sandip, Chakraborty, Molee, Ulmasov, Barbara, McCommis, Kyle, Zhang, Jinsong, Carpenter, Danielle, Msengi, Eliwaza Naomi, Haubner, Jake, Guo, Chun, Pike, Daniel P., Ghoshal, Sarbani, Ford, David A., Neuschwander-Tetri, Brent A., Chakraborty, Anutosh
Publicado 2021

NAT10 Maintains OGA mRNA Stability Through ac4C Modification in Regulating Oocyte Maturation

por Lin, Jiayu, Xiang, Yuting, Huang, Jiana, Zeng, Haitao, Zeng, Yanyan, Liu, Jiawen, Wu, Taibao, Liang, Qiqi, Liang, Xiaoyan, Li, Jingjie, Zhou, Chuanchuan
Publicado 2022

Penta-o-galloyl-beta-d-Glucose (PGG) inhibits inflammation in human rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis model

por Umar, Sadiq, Singh, Anil K., Chourasia, Mukesh, Rasmussen, Stephanie M., Ruth, Jeffrey H., Ahmed, Salahuddin
Publicado 2022

Protein O-GlcNAcylation and the regulation of energy homeostasis: lessons from knock-out mouse models

por Issad, Tarik, Al-Mukh, Hasanain, Bouaboud, Abdelouhab, Pagesy, Patrick
Publicado 2022

O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis

por Soria, Leandro R., Makris, Georgios, D’Alessio, Alfonso M., De Angelis, Angela, Boffa, Iolanda, Pravata, Veronica M., Rüfenacht, Véronique, Attanasio, Sergio, Nusco, Edoardo, Arena, Paola, Ferenbach, Andrew T., Paris, Debora, Cuomo, Paola, Motta, Andrea, Nitzahn, Matthew, Lipshutz, Gerald S., Martínez-Pizarro, Ainhoa, Richard, Eva, Desviat, Lourdes R., Häberle, Johannes, van Aalten, Daan M. F., Brunetti-Pierri, Nicola
Publicado 2022

Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis in vivo

por Jo, Seokwon, Pritchard, Samantha, Wong, Alicia, Avula, Nandini, Essawy, Ahmad, Hanover, John, Alejandro, Emilyn U.
Publicado 2022

Investigation of in vitro histone H3 glycosylation using H3 tail peptides

por Merx, Jona, Hintzen, Jordi C. J., Proietti, Giordano, Elferink, Hidde, Wang, Yali, Porzberg, Miriam R. B., Sondag, Daan, Bilgin, Nurgül, Park, Jin, Mecinović, Jasmin, Boltje, Thomas J.
Publicado 2022