DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity

por Anchang, Benedict, Davis, Kara L., Fienberg, Harris G., Williamson, Brian D., Bendall, Sean C., Karacosta, Loukia G., Tibshirani, Robert, Nolan, Garry P., Plevritis, Sylvia K.
Publicado 2018

Urbanization prolongs hantavirus epidemics in cities

por Tian, Huaiyu, Hu, Shixiong, Cazelles, Bernard, Chowell, Gerardo, Gao, Lidong, Laine, Marko, Li, Yapin, Yang, Huisuo, Li, Yidan, Yang, Qiqi, Tong, Xin, Huang, Ru, Bjornstad, Ottar N., Xiao, Hong, Stenseth, Nils Chr.
Publicado 2018

Synthetically engineered Medea gene drive system in the worldwide crop pest Drosophila suzukii

por Buchman, Anna, Marshall, John M., Ostrovski, Dennis, Yang, Ting, Akbari, Omar S.
Publicado 2018

Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses

por Deng, Tanggang, Yan, Guobei, Song, Xin, Xie, Lin, Zhou, Yu, Li, Jianglin, Hu, Xiaoxiao, Li, Zhen, Hu, Jun, Zhang, Yibin, Zhang, Hui, Sun, Yang, Feng, Peifu, Wei, Dong, Hu, Bin, Liu, Jing, Tan, Weihong, Ye, Mao
Publicado 2018

Polysialic acid is a cellular receptor for human adenovirus 52

por Lenman, Annasara, Liaci, A. Manuel, Liu, Yan, Frängsmyr, Lars, Frank, Martin, Blaum, Bärbel S., Chai, Wengang, Podgorski, Iva I., Harrach, Balázs, Benkő, Mária, Feizi, Ten, Stehle, Thilo, Arnberg, Niklas
Publicado 2018

An explainable deep machine vision framework for plant stress phenotyping

por Ghosal, Sambuddha, Blystone, David, Singh, Asheesh K., Ganapathysubramanian, Baskar, Singh, Arti, Sarkar, Soumik
Publicado 2018

Drought delays development of the sorghum root microbiome and enriches for monoderm bacteria

por Xu, Ling, Naylor, Dan, Dong, Zhaobin, Simmons, Tuesday, Pierroz, Grady, Hixson, Kim K., Kim, Young-Mo, Zink, Erika M., Engbrecht, Kristin M., Wang, Yi, Gao, Cheng, DeGraaf, Stephanie, Madera, Mary A., Sievert, Julie A., Hollingsworth, Joy, Birdseye, Devon, Scheller, Henrik V., Hutmacher, Robert, Dahlberg, Jeffery, Jansson, Christer, Taylor, John W., Lemaux, Peggy G., Coleman-Derr, Devin
Publicado 2018

Individuals, institutions, and innovation in the debates of the French Revolution

por Barron, Alexander T. J., Huang, Jenny, Spang, Rebecca L., DeDeo, Simon
Publicado 2018

Integrating effects of species composition and soil properties to predict shifts in montane forest carbon–water relations

por Maxwell, Toby M., Silva, Lucas C. R., Horwath, William R.
Publicado 2018

Spatial determinants of quorum signaling in a Pseudomonas aeruginosa infection model

por Darch, Sophie E., Simoska, Olja, Fitzpatrick, Mignon, Barraza, Juan P., Stevenson, Keith J., Bonnecaze, Roger T., Shear, Jason B., Whiteley, Marvin
Publicado 2018

Draft genome sequence of Camellia sinensis var. sinensis provides insights into the evolution of the tea genome and tea quality

por Wei, Chaoling, Yang, Hua, Wang, Songbo, Zhao, Jian, Liu, Chun, Gao, Liping, Xia, Enhua, Lu, Ying, Tai, Yuling, She, Guangbiao, Sun, Jun, Cao, Haisheng, Tong, Wei, Gao, Qiang, Li, Yeyun, Deng, Weiwei, Jiang, Xiaolan, Wang, Wenzhao, Chen, Qi, Zhang, Shihua, Li, Haijing, Wu, Junlan, Wang, Ping, Li, Penghui, Shi, Chengying, Zheng, Fengya, Jian, Jianbo, Huang, Bei, Shan, Dai, Shi, Mingming, Fang, Congbing, Yue, Yi, Li, Fangdong, Li, Daxiang, Wei, Shu, Han, Bin, Jiang, Changjun, Yin, Ye, Xia, Tao, Zhang, Zhengzhu, Bennetzen, Jeffrey L., Zhao, Shancen, Wan, Xiaochun
Publicado 2018

Rapid selection of a pyrethroid metabolic enzyme CYP9K1 by operational malaria control activities

por Vontas, John, Grigoraki, Linda, Morgan, John, Tsakireli, Dimitra, Fuseini, Godwin, Segura, Luis, Niemczura de Carvalho, Julie, Nguema, Raul, Weetman, David, Slotman, Michel A., Hemingway, Janet
Publicado 2018

MinE conformational switching confers robustness on self-organized Min protein patterns

por Denk, Jonas, Kretschmer, Simon, Halatek, Jacob, Hartl, Caroline, Schwille, Petra, Frey, Erwin
Publicado 2018

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers

por Udugama, Maheshi, Sanij, Elaine, Voon, Hsiao P. J., Son, Jinbae, Hii, Linda, Henson, Jeremy D., Chan, F. Lyn, Chang, Fiona T. M., Liu, Yumei, Pearson, Richard B., Kalitsis, Paul, Mann, Jeffrey R., Collas, Philippe, Hannan, Ross D., Wong, Lee H.
Publicado 2018

Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species

por Wang, Xue, Zhou, Haibo, Chen, Hanna, Jing, Xiaoshu, Zheng, Wentao, Li, Ruijuan, Sun, Tao, Liu, Jiaqi, Fu, Jun, Huo, Liujie, Li, Yue-zhong, Shen, Yuemao, Ding, Xiaoming, Müller, Rolf, Bian, Xiaoying, Zhang, Youming
Publicado 2018

Digitizing omics profiles by divergence from a baseline

por Dinalankara, Wikum, Ke, Qian, Xu, Yiran, Ji, Lanlan, Pagane, Nicole, Lien, Anching, Matam, Tejasvi, Fertig, Elana J., Price, Nathan D., Younes, Laurent, Marchionni, Luigi, Geman, Donald
Publicado 2018

O(6)-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

por Ezerskyte, Monika, Paredes, João A., Malvezzi, Stefano, Burns, John A., Margison, Geoffrey P., Olsson, Magnus, Scicchitano, David A., Dreij, Kristian
Publicado 2018

Shared epitope–aryl hydrocarbon receptor crosstalk underlies the mechanism of gene–environment interaction in autoimmune arthritis

por Fu, Jiaqi, Nogueira, Sarah V., van Drongelen, Vincent, Coit, Patrick, Ling, Song, Rosloniec, Edward F., Sawalha, Amr H., Holoshitz, Joseph
Publicado 2018

Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor

por Malia, PC, Numrich, Johannes, Nishimura, Taki, González Montoro, Ayelén, Stefan, Christopher J., Ungermann, Christian
Publicado 2018

Thermally stable, highly efficient, ultraflexible organic photovoltaics

por Xu, Xiaomin, Fukuda, Kenjiro, Karki, Akchheta, Park, Sungjun, Kimura, Hiroki, Jinno, Hiroaki, Watanabe, Nobuhiro, Yamamoto, Shuhei, Shimomura, Satoru, Kitazawa, Daisuke, Yokota, Tomoyuki, Umezu, Shinjiro, Nguyen, Thuc-Quyen, Someya, Takao
Publicado 2018