Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis

por Eshaghi, Arman, Kievit, Rogier A., Prados, Ferran, Sudre, Carole H., Nicholas, Jennifer, Cardoso, M. Jorge, Chan, Dennis, Nicholas, Richard, Ourselin, Sebastien, Greenwood, John, Thompson, Alan J., Alexander, Daniel C., Barkhof, Frederik, Chataway, Jeremy, Ciccarelli, Olga
Publicado 2019

Long-range mobile signals mediate seasonal control of shoot growth

por Miskolczi, Pál, Singh, Rajesh Kumar, Tylewicz, Szymon, Azeez, Abdul, Maurya, Jay P., Tarkowská, Danuše, Novák, Ondřej, Jonsson, Kristoffer, Bhalerao, Rishikesh P.
Publicado 2019

Solving the structure of Lgl2, a difficult blind test of unsupervised structure determination

por Ufimtsev, Ivan S., Almagor, Lior, Weis, William I., Levitt, Michael
Publicado 2019

Unraveling ancestry, kinship, and violence in a Late Neolithic mass grave

por Schroeder, Hannes, Margaryan, Ashot, Szmyt, Marzena, Theulot, Bertrand, Włodarczak, Piotr, Rasmussen, Simon, Gopalakrishnan, Shyam, Szczepanek, Anita, Konopka, Tomasz, Jensen, Theis Z. T., Witkowska, Barbara, Wilk, Stanisław, Przybyła, Marcin M., Pospieszny, Łukasz, Sjögren, Karl-Göran, Belka, Zdzislaw, Olsen, Jesper, Kristiansen, Kristian, Willerslev, Eske, Frei, Karin M., Sikora, Martin, Johannsen, Niels N., Allentoft, Morten E.
Publicado 2019

Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity

por Gattu, Sureka, Bang, Ye-Ji, Pendse, Mihir, Dende, Chaitanya, Chara, Andrew L., Harris, Tamia A., Wang, Yuhao, Ruhn, Kelly A., Kuang, Zheng, Sockanathan, Shanthini, Hooper, Lora V.
Publicado 2019

Rates of niche and phenotype evolution lag behind diversification in a temperate radiation

por Folk, Ryan A., Stubbs, Rebecca L., Mort, Mark E., Cellinese, Nico, Allen, Julie M., Soltis, Pamela S., Soltis, Douglas E., Guralnick, Robert P.
Publicado 2019

Hatchet ribozyme structure and implications for cleavage mechanism

por Zheng, Luqian, Falschlunger, Christoph, Huang, Kaiyi, Mairhofer, Elisabeth, Yuan, Shuguang, Wang, Juncheng, Patel, Dinshaw J., Micura, Ronald, Ren, Aiming
Publicado 2019

Caulobacter crescentus Hfq structure reveals a conserved mechanism of RNA annealing regulation

por Santiago-Frangos, Andrew, Fröhlich, Kathrin S., Jeliazkov, Jeliazko R., Małecka, Ewelina M., Marino, Giada, Gray, Jeffrey J., Luisi, Ben F., Woodson, Sarah A., Hardwick, Steven W.
Publicado 2019

Distinct differences in the nanoscale behaviors of the twist–bend liquid crystal phase of a flexible linear trimer and homologous dimer

por Tuchband, Michael R., Paterson, Daniel A., Salamończyk, Mirosław, Norman, Victoria A., Scarbrough, Alyssa N., Forsyth, Ewan, Garcia, Edgardo, Wang, Cheng, Storey, John M. D., Walba, David M., Sprunt, Samuel, Jákli, Antal, Zhu, Chenhui, Imrie, Corrie T., Clark, Noel A.
Publicado 2019

CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis

por Arends, Tessa, Dege, Carissa, Bortnick, Alexandra, Danhorn, Thomas, Knapp, Jennifer R., Jia, Haiqun, Harmacek, Laura, Fleenor, Courtney J., Straign, Desiree, Walton, Kendra, Leach, Sonia M., Feeney, Ann J., Murre, Cornelis, O’Connor, Brian P., Hagman, James R.
Publicado 2019

Serotonin regulates mitochondrial biogenesis and function in rodent cortical neurons via the 5-HT(2A) receptor and SIRT1–PGC-1α axis

por Fanibunda, Sashaina E., Deb, Sukrita, Maniyadath, Babukrishna, Tiwari, Praachi, Ghai, Utkarsha, Gupta, Samir, Figueiredo, Dwight, Weisstaub, Noelia, Gingrich, Jay A., Vaidya, Ashok D. B., Kolthur-Seetharam, Ullas, Vaidya, Vidita A.
Publicado 2019

sGC stimulator praliciguat suppresses stellate cell fibrotic transformation and inhibits fibrosis and inflammation in models of NASH

por Hall, Katherine C., Bernier, Sylvie G., Jacobson, Sarah, Liu, Guang, Zhang, Ping Y., Sarno, Renee, Catanzano, Victoria, Currie, Mark G., Masferrer, Jaime L.
Publicado 2019

Possible observation of quantum spin-nematic phase in a frustrated magnet

por Kohama, Yoshimitsu, Ishikawa, Hajime, Matsuo, Akira, Kindo, Koichi, Shannon, Nic, Hiroi, Zenji
Publicado 2019

IKKβ slows Huntington’s disease progression in R6/1 mice

por Ochaba, Joseph, Fote, Gianna, Kachemov, Marketta, Thein, Soe, Yeung, Sylvia Y., Lau, Alice L., Hernandez, Sarah, Lim, Ryan G., Casale, Malcolm, Neel, Michael J., Monuki, Edwin S., Reidling, Jack, Housman, David E., Thompson, Leslie M., Steffan, Joan S.
Publicado 2019

Objecting to experiments that compare two unobjectionable policies or treatments

por Meyer, Michelle N., Heck, Patrick R., Holtzman, Geoffrey S., Anderson, Stephen M., Cai, William, Watts, Duncan J., Chabris, Christopher F.
Publicado 2019

Decreasing measles burden by optimizing campaign timing

por Thakkar, Niket, Gilani, Syed Saqlain Ahmad, Hasan, Quamrul, McCarthy, Kevin A.
Publicado 2019

Reply to Snowdon et al. and Piepho: Genetic response diversity to provide yield stability of cultivar groups deserves attention

por Kahiluoto, Helena, Kaseva, Janne, Olesen, Jørgen E., Kersebaum, Kurt Christian, Ruiz-Ramos, Margarita, Gobin, Anne, Takáč, Jozef, Ruget, Francoise, Ferrise, Roberto, Balek, Jan, Bezak, Pavol, Capellades, Gemma, Dibari, Camilla, Mäkinen, Hanna, Nendel, Claas, Ventrella, Domenico, Rodríguez, Alfredo, Bindi, Marco, Trnka, Mirek
Publicado 2019

Unsupervised determination of protein crystal structures

por Ufimtsev, Ivan S., Levitt, Michael
Publicado 2019

Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization

por Wang, Chong, Lu, Tian, Emanuel, George, Babcock, Hazen P., Zhuang, Xiaowei
Publicado 2019

Elasticity of individual protocadherin 15 molecules implicates tip links as the gating springs for hearing

por Bartsch, Tobias F., Hengel, Felicitas E., Oswald, Aaron, Dionne, Gilman, Chipendo, Iris V., Mangat, Simranjit S., El Shatanofy, Muhammad, Shapiro, Lawrence, Müller, Ulrich, Hudspeth, A. J.
Publicado 2019