An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

por Longo, Joseph, Mullen, Peter J., Yu, Rosemary, van Leeuwen, Jenna E., Masoomian, Mehdi, Woon, Dixon T.S., Wang, Yuzhuo, Chen, Eric X., Hamilton, Robert J., Sweet, Joan M., van der Kwast, Theodorus H., Fleshner, Neil E., Penn, Linda Z.
Publicado 2019

Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

por Yang, Nan, Smyllie, Nicola J., Morris, Honor, Gonçalves, Cátia F., Dudek, Michal, Pathiranage, Dharshika R. J., Chesham, Johanna E., Adamson, Antony, Spiller, David G., Zindy, Egor, Bagnall, James, Humphreys, Neil, Hoyland, Judith, Loudon, Andrew S. I., Hastings, Michael H., Meng, Qing-Jun
Publicado 2020

Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity

por Myers, Darienne R., Abram, Clare L., Wildes, David, Belwafa, Amira, Welsh, Alia M. N., Schulze, Christopher J., Choy, Tiffany J., Nguyen, Tram, Omaque, Neil, Hu, Yongmei, Singh, Mallika, Hansen, Rich, Goldsmith, Mark A., Quintana, Elsa, Smith, Jacqueline A. M., Lowell, Clifford A.
Publicado 2020

Response to COVID-19 in South Korea and implications for lifting stringent interventions

por Dighe, Amy, Cattarino, Lorenzo, Cuomo-Dannenburg, Gina, Skarp, Janetta, Imai, Natsuko, Bhatia, Sangeeta, Gaythorpe, Katy A. M., Ainslie, Kylie E. C., Baguelin, Marc, Bhatt, Samir, Boonyasiri, Adhiratha, Brazeau, Nicholas F., Cooper, Laura V., Coupland, Helen, Cucunuba, Zulma, Dorigatti, Ilaria, Eales, Oliver D., van Elsland, Sabine L., FitzJohn, Richard G., Green, William D., Haw, David J., Hinsley, Wes, Knock, Edward, Laydon, Daniel J., Mellan, Thomas, Mishra, Swapnil, Nedjati-Gilani, Gemma, Nouvellet, Pierre, Pons-Salort, Margarita, Thompson, Hayley A., Unwin, H. Juliette T., Verity, Robert, Vollmer, Michaela A. C., Walters, Caroline E., Watson, Oliver J., Whittaker, Charles, Whittles, Lilith K., Ghani, Azra C., Donnelly, Christl A., Ferguson, Neil M., Riley, Steven
Publicado 2020

Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia

por Nii, Takenobu, Prabhu, Varun V., Ruvolo, Vivian, Madhukar, Neel, Zhao, Ran, Mu, Hong, Heese, Lauren, Nishida, Yuki, Kojima, Kensuke, Garnett, Mathew J., McDermott, Ultan, Benes, Cyril H., Charter, Neil, Deacon, Sean, Elemento, Olivier, Allen, Joshua E., Oster, Wolfgang, Stogniew, Martin, Ishizawa, Jo, Andreeff, Michael
Publicado 2019

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

por Gan, Wenjian, Dai, Xiaoming, Dai, Xiangpeng, Xie, Jun, Yin, Shasha, Zhu, Junjie, Wang, Chen, Liu, Yuchen, Guo, Jianping, Wang, Min, Liu, Jing, Hu, Jia, Quinton, Ryan J., Ganem, Neil J., Liu, Pengda, Asara, John M., Pandolfi, Pier Paolo, Yang, Yingzi, He, Zhigang, Gao, Guangping, Wei, Wenyi
Publicado 2020

Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells

por Matthews, Olivia, Morrison, Emma E., Tranter, John D., Starkey Lewis, Philip, Toor, Iqbal S., Srivastava, Abhishek, Sargeant, Rebecca, Rollison, Helen, Matchett, Kylie P., Kendall, Timothy J., Gray, Gillian A., Goldring, Chris, Park, Kevin, Denby, Laura, Dhaun, Neeraj, Bailey, Matthew A., Henderson, Neil C., Williams, Dominic, Dear, James W.
Publicado 2020

The impact of COVID-19 and strategies for mitigation and suppression in low- and middle-income countries

por Walker, Patrick G. T., Whittaker, Charles, Watson, Oliver J., Baguelin, Marc, Winskill, Peter, Hamlet, Arran, Djafaara, Bimandra A., Cucunubá, Zulma, Olivera Mesa, Daniela, Green, Will, Thompson, Hayley, Nayagam, Shevanthi, Ainslie, Kylie E. C., Bhatia, Sangeeta, Bhatt, Samir, Boonyasiri, Adhiratha, Boyd, Olivia, Brazeau, Nicholas F., Cattarino, Lorenzo, Cuomo-Dannenburg, Gina, Dighe, Amy, Donnelly, Christl A., Dorigatti, Ilaria, van Elsland, Sabine L., FitzJohn, Rich, Fu, Han, Gaythorpe, Katy A. M., Geidelberg, Lily, Grassly, Nicholas, Haw, David, Hayes, Sarah, Hinsley, Wes, Imai, Natsuko, Jorgensen, David, Knock, Edward, Laydon, Daniel, Mishra, Swapnil, Nedjati-Gilani, Gemma, Okell, Lucy C., Unwin, H. Juliette, Verity, Robert, Vollmer, Michaela, Walters, Caroline E., Wang, Haowei, Wang, Yuanrong, Xi, Xiaoyue, Lalloo, David G., Ferguson, Neil M., Ghani, Azra C.
Publicado 2020

Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia

por Almotiri, Alhomidi, Alzahrani, Hamed, Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia, Gibbs, Alex, Alsayari, Amani, Taha, Sarab, Thomas, Leigh-anne, Shah, Dhruv, Edkins, Sarah, Giles, Peter, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian A., Rodrigues, Neil P.
Publicado 2021

SARS-CoV-2 infection prevalence on repatriation flights from Wuhan City, China

por Thompson, Hayley A, Imai, Natsuko, Dighe, Amy, Ainslie, Kylie E C, Baguelin, Marc, Bhatia, Sangeeta, Bhatt, Samir, Boonyasiri, Adhiratha, Boyd, Olivia, Brazeau, Nicholas F, Cattarino, Lorenzo, Cooper, Laura V, Coupland, Helen, Cucunuba, Zulma, Cuomo-Dannenburg, Gina, Djaafara, Bimandra, Dorigatti, Ilaria, van Elsland, Sabine, FitzJohn, Richard, Fu, Han, Gaythorpe, Katy A M, Green, Will, Hallett, Timothy, Hamlet, Arran, Haw, David, Hayes, Sarah, Hinsley, Wes, Jeffrey, Benjamin, Knock, Edward, Laydon, Daniel J, Lees, John, Mangal, Tara D, Mellan, Thomas, Mishra, Swapnil, Mousa, Andria, Nedjati-Gilani, Gemma, Nouvellet, Pierre, Okell, Lucy, Parag, Kris V, Ragonnet-Cronin, Manon, Riley, Steven, Unwin, H Juliette T, Verity, Robert, Vollmer, Michaela, Volz, Erik, Walker, Patrick G T, Walters, Caroline, Wang, Haowei, Wang, Yuanrong, Watson, Oliver J, Whittaker, Charles, Whittles, Lilith K, Winskill, Peter, Xi, Xiaoyue, Donnelly, Christl A, Ferguson, Neil M
Publicado 2020

State-level tracking of COVID-19 in the United States

por Unwin, H. Juliette T., Mishra, Swapnil, Bradley, Valerie C., Gandy, Axel, Mellan, Thomas A., Coupland, Helen, Ish-Horowicz, Jonathan, Vollmer, Michaela A. C., Whittaker, Charles, Filippi, Sarah L., Xi, Xiaoyue, Monod, Mélodie, Ratmann, Oliver, Hutchinson, Michael, Valka, Fabian, Zhu, Harrison, Hawryluk, Iwona, Milton, Philip, Ainslie, Kylie E. C., Baguelin, Marc, Boonyasiri, Adhiratha, Brazeau, Nick F., Cattarino, Lorenzo, Cucunuba, Zulma, Cuomo-Dannenburg, Gina, Dorigatti, Ilaria, Eales, Oliver D., Eaton, Jeffrey W., van Elsland, Sabine L., FitzJohn, Richard G., Gaythorpe, Katy A. M., Green, William, Hinsley, Wes, Jeffrey, Benjamin, Knock, Edward, Laydon, Daniel J., Lees, John, Nedjati-Gilani, Gemma, Nouvellet, Pierre, Okell, Lucy, Parag, Kris V., Siveroni, Igor, Thompson, Hayley A., Walker, Patrick, Walters, Caroline E., Watson, Oliver J., Whittles, Lilith K., Ghani, Azra C., Ferguson, Neil M., Riley, Steven, Donnelly, Christl A., Bhatt, Samir, Flaxman, Seth
Publicado 2020

Reduction in mobility and COVID-19 transmission

por Nouvellet, Pierre, Bhatia, Sangeeta, Cori, Anne, Ainslie, Kylie E. C., Baguelin, Marc, Bhatt, Samir, Boonyasiri, Adhiratha, Brazeau, Nicholas F., Cattarino, Lorenzo, Cooper, Laura V., Coupland, Helen, Cucunuba, Zulma M., Cuomo-Dannenburg, Gina, Dighe, Amy, Djaafara, Bimandra A., Dorigatti, Ilaria, Eales, Oliver D., van Elsland, Sabine L., Nascimento, Fabricia F., FitzJohn, Richard G., Gaythorpe, Katy A. M., Geidelberg, Lily, Green, William D., Hamlet, Arran, Hauck, Katharina, Hinsley, Wes, Imai, Natsuko, Jeffrey, Benjamin, Knock, Edward, Laydon, Daniel J., Lees, John A., Mangal, Tara, Mellan, Thomas A., Nedjati-Gilani, Gemma, Parag, Kris V., Pons-Salort, Margarita, Ragonnet-Cronin, Manon, Riley, Steven, Unwin, H. Juliette T., Verity, Robert, Vollmer, Michaela A. C., Volz, Erik, Walker, Patrick G. T., Walters, Caroline E., Wang, Haowei, Watson, Oliver J., Whittaker, Charles, Whittles, Lilith K., Xi, Xiaoyue, Ferguson, Neil M., Donnelly, Christl A.
Publicado 2021

A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C

por Huang, Huiyan, Pan, Jiehong, Spielberg, David R., Hanchard, Neil A., Scott, Daryl A., Burrage, Lindsay C., Dai, Hongzheng, Murdock, David, Rosenfeld, Jill A., Mohammad, Ariz, Huang, Tao, Lindsey, Anika G., Kim, Hyori, Chen, Jian, Ramu, Avinash, Morrison, Stephanie A., Dawson, Zachary D., Hu, Alex Z., Tycksen, Eric, Silverman, Gary A., Baldridge, Dustin, Wambach, Jennifer A., Pak, Stephen C., Brody, Steven L., Schedl, Tim
Publicado 2022

Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease

por Menalled, Liliana B., Kudwa, Andrea E., Oakeshott, Steve, Farrar, Andrew, Paterson, Neil, Filippov, Igor, Miller, Sam, Kwan, Mei, Olsen, Michael, Beltran, Jose, Torello, Justin, Fitzpatrick, Jon, Mushlin, Richard, Cox, Kimberly, McConnell, Kristi, Mazzella, Matthew, He, Dansha, Osborne, Georgina F., Al-Nackkash, Rand, Bates, Gill P., Tuunanen, Pasi, Lehtimaki, Kimmo, Brunner, Dani, Ghavami, Afshin, Ramboz, Sylvie, Park, Larry, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Howland, David
Publicado 2014

An Endogenous Nanomineral Chaperones Luminal Antigen and Peptidoglycan to Intestinal Immune Cells

por Powell, Jonathan J, Thomas-McKay, Emma, Thoree, Vinay, Robertson, Jack, Hewitt, Rachel E, Skepper, Jeremy N, Brown, Andy, Hernandez-Garrido, Juan Carlos, Midgley, Paul A, Gomez-Morilla, Inmaculada, Grime, Geoffrey W, Kirkby, Karen J, Mabbott, Neil A, Donaldson, David S, Williams, Ifor R, Rios, Daniel, Girardin, Stephen E, Haas, Carolin T, Bruggraber, Sylvaine FA, Laman, Jon D, Tanriver, Yakup, Lombardi, Giovanna, Lechler, Robert, Thompson, Richard P H, Pele, Laetitia C
Publicado 2015

A Central Support System Can Facilitate Implementation and Sustainability of a Classroom-Based Undergraduate Research Experience (CURE) in Genomics

por Lopatto, David, Hauser, Charles, Jones, Christopher J., Paetkau, Don, Chandrasekaran, Vidya, Dunbar, David, MacKinnon, Christy, Stamm, Joyce, Alvarez, Consuelo, Barnard, Daron, Bedard, James E. J., Bednarski, April E., Bhalla, Satish, Braverman, John M., Burg, Martin, Chung, Hui-Min, DeJong, Randall J., DiAngelo, Justin R., Du, Chunguang, Eckdahl, Todd T., Emerson, Julia, Frary, Amy, Frohlich, Donald, Goodman, Anya L., Gosser, Yuying, Govind, Shubha, Haberman, Adam, Hark, Amy T., Hoogewerf, Arlene, Johnson, Diana, Kadlec, Lisa, Kaehler, Marian, Key, S. Catherine Silver, Kokan, Nighat P., Kopp, Olga R., Kuleck, Gary A., Lopilato, Jane, Martinez-Cruzado, Juan C., McNeil, Gerard, Mel, Stephanie, Nagengast, Alexis, Overvoorde, Paul J., Parrish, Susan, Preuss, Mary L., Reed, Laura D., Regisford, E. Gloria, Revie, Dennis, Robic, Srebrenka, Roecklien-Canfield, Jennifer A., Rosenwald, Anne G., Rubin, Michael R., Saville, Kenneth, Schroeder, Stephanie, Sharif, Karim A., Shaw, Mary, Skuse, Gary, Smith, Christopher D., Smith, Mary, Smith, Sheryl T., Spana, Eric P., Spratt, Mary, Sreenivasan, Aparna, Thompson, Jeffrey S., Wawersik, Matthew, Wolyniak, Michael J., Youngblom, James, Zhou, Leming, Buhler, Jeremy, Mardis, Elaine, Leung, Wilson, Shaffer, Christopher D., Threlfall, Jennifer, Elgin, Sarah C. R.
Publicado 2014

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

por White, Jacqueline K., Gerdin, Anna-Karin, Karp, Natasha A., Ryder, Ed, Buljan, Marija, Bussell, James N., Salisbury, Jennifer, Clare, Simon, Ingham, Neil J., Podrini, Christine, Houghton, Richard, Estabel, Jeanne, Bottomley, Joanna R., Melvin, David G., Sunter, David, Adams, Niels C., Tannahill, David, Logan, Darren W., MacArthur, Daniel G., Flint, Jonathan, Mahajan, Vinit B., Tsang, Stephen H., Smyth, Ian, Watt, Fiona M., Skarnes, William C., Dougan, Gordon, Adams, David J., Ramirez-Solis, Ramiro, Bradley, Allan, Steel, Karen P.
Publicado 2013

Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses

por Dijokaite-Guraliuc, Aiste, Das, Raksha, Zhou, Daming, Ginn, Helen M., Liu, Chang, Duyvesteyn, Helen M.E., Huo, Jiandong, Nutalai, Rungtiwa, Supasa, Piyada, Selvaraj, Muneeswaran, de Silva, Thushan I., Plowright, Megan, Newman, Thomas A.H., Hornsby, Hailey, Mentzer, Alexander J., Skelly, Donal, Ritter, Thomas G., Temperton, Nigel, Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Roemer, Cornelius, Peacock, Thomas P., Paterson, Neil G., Williams, Mark A., Hall, David R., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2023

A Course-Based Research Experience: How Benefits Change with Increased Investment in Instructional Time

por Shaffer, Christopher D., Alvarez, Consuelo J., Bednarski, April E., Dunbar, David, Goodman, Anya L., Reinke, Catherine, Rosenwald, Anne G., Wolyniak, Michael J., Bailey, Cheryl, Barnard, Daron, Bazinet, Christopher, Beach, Dale L., Bedard, James E. J., Bhalla, Satish, Braverman, John, Burg, Martin, Chandrasekaran, Vidya, Chung, Hui-Min, Clase, Kari, DeJong, Randall J., DiAngelo, Justin R., Du, Chunguang, Eckdahl, Todd T., Eisler, Heather, Emerson, Julia A., Frary, Amy, Frohlich, Donald, Gosser, Yuying, Govind, Shubha, Haberman, Adam, Hark, Amy T., Hauser, Charles, Hoogewerf, Arlene, Hoopes, Laura L. M., Howell, Carina E., Johnson, Diana, Jones, Christopher J., Kadlec, Lisa, Kaehler, Marian, Silver Key, S. Catherine, Kleinschmit, Adam, Kokan, Nighat P., Kopp, Olga, Kuleck, Gary, Leatherman, Judith, Lopilato, Jane, MacKinnon, Christy, Martinez-Cruzado, Juan Carlos, McNeil, Gerard, Mel, Stephanie, Mistry, Hemlata, Nagengast, Alexis, Overvoorde, Paul, Paetkau, Don W., Parrish, Susan, Peterson, Celeste N., Preuss, Mary, Reed, Laura K., Revie, Dennis, Robic, Srebrenka, Roecklein-Canfield, Jennifer, Rubin, Michael R., Saville, Kenneth, Schroeder, Stephanie, Sharif, Karim, Shaw, Mary, Skuse, Gary, Smith, Christopher D., Smith, Mary A., Smith, Sheryl T., Spana, Eric, Spratt, Mary, Sreenivasan, Aparna, Stamm, Joyce, Szauter, Paul, Thompson, Jeffrey S., Wawersik, Matthew, Youngblom, James, Zhou, Leming, Mardis, Elaine R., Buhler, Jeremy, Leung, Wilson, Lopatto, David, Elgin, Sarah C. R.
Publicado 2014

Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

por Wang, Lin, Aschenbrenner, Dominik, Zeng, Zhiyang, Cao, Xiya, Mayr, Daniel, Mehta, Meera, Capitani, Melania, Warner, Neil, Pan, Jie, Wang, Liren, Li, Qi, Zuo, Tao, Cohen-Kedar, Sarit, Lu, Jiawei, Ardy, Rico Chandra, Mulder, Daniel J., Dissanayake, Dilan, Peng, Kaiyue, Huang, Zhiheng, Li, Xiaoqin, Wang, Yuesheng, Wang, Xiaobing, Li, Shuchao, Bullers, Samuel, Gammage, Anís N., Warnatz, Klaus, Schiefer, Ana-Iris, Krivan, Gergely, Goda, Vera, Kahr, Walter H.A., Lemaire, Mathieu, Lu, Chien-Yi, Siddiqui, Iram, Surette, Michael G., Kotlarz, Daniel, Engelhardt, Karin R., Griffin, Helen R., Rottapel, Robert, Decaluwe, Hélène, Laxer, Ronald M., Proietti, Michele, Hambleton, Sophie, Elcombe, Suzanne, Guo, Cong-Hui, Grimbacher, Bodo, Dotan, Iris, Ng, Siew C., Freeman, Spencer A., Snapper, Scott B., Klein, Christoph, Boztug, Kaan, Huang, Ying, Li, Dali, Uhlig, Holm H., Muise, Aleixo M.
Publicado 2021