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501“…INTRODUCTION: The transition to primary school is a significant milestone for children. Transition periods can offer new opportunities to build skills, relationships, and experiences that strengthen self-efficacy. …”
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502“…The pandemic of new coronavirus disease COVID-19 is threatening our health, economy and life style. …”
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503por Coste, Alix T., Egli, Adrian, Schrenzel, Jacques, Nickel, Beatrice, Zbinden, Andrea, Lienhard, Reto, Dumoulin, Alexis, Risch, Martin, Greub, Gilbert“…The regular emergence of new pathogens (including Echovirus E-11, Adenovirus 41, Monkeypox virus, Alongshan virus, and Enterovirus D68, as recent examples in Europe in the post SARS-CoV-2 era) is another factor that makes IVDR regulation risky, because its detrimental effect on production of in-house tests will negatively impact knowledge and expertise in the development of new diagnostic tests. …”
Publicado 2023
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504“…With the discovery of cisplatin by Barnett Rosenberg in 1960, a milestone in the history of metal-based compounds used in the treatment of cancers was witnessed. …”
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505“…The repurposing of old drugs for new indications is becoming more accepted as a cost-efficient solution for complicated health problems. …”
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506“…Key recommendations to SAHPRA to ensure the full potential of the new regulatory environment in South Africa include: establishing a quality management system to safeguard accountability, consistency and transparency and to streamline the implementation of good review practices including quality decision-making practices and benefit-risk assessment; the measurement and monitoring of regulatory performance, targets for overall approval time and key review milestones to instill a culture of accurate metrics collection and measurement of key performance indicators and their continuous improvement and the employment of a risk-based approach to the evaluation of medical products and codify the use of facilitated regulatory pathways in policy and culture. …”
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507por Balasco, Nicole, Diaferia, Carlo, Morelli, Giancarlo, Vitagliano, Luigi, Accardo, Antonella“…Interestingly, the progressive molecular and structural characterization of these assemblies has opened new perspectives in apparently unrelated fields. …”
Publicado 2021
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508por Faber, Randall, Feller, Christina N., Gofman, Natalie, Fletcher, John, Hedayat, Hirad S.“…At 8-month follow-up, the patient continued to meet developmental milestones with near resolution of his dysconjugate gaze. …”
Publicado 2021
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509por Cazzato, Gerardo, Ambrogio, Francesca, Pisani, Maria Carla, Colagrande, Anna, Arezzo, Francesca, Cascardi, Eliano, Dellino, Miriam, Macorano, Enrica, Trilli, Irma, Parente, Paola, Lettini, Teresa, Romita, Paolo, Marzullo, Andrea, Ingravallo, Giuseppe, Foti, Caterina“…The advent of vaccines represented a milestone to allow the slowing down and then containing of the exponential increase in ongoing infections and deaths of COVID-19. …”
Publicado 2023
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510por Leimbach, David“…However, its chemical properties are yet to be determined due to the short life time of astatine. A milestone towards the determination of the electronegativity of astatine was the measurement of its ionization potential (IP) at CERN-ISOLDE. …”
Publicado 2018
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511por Clémençon, Benjamin, Lüscher, Benjamin P., Fine, Michael, Baumann, Marc U., Surbek, Daniel V., Bonny, Olivier, Hediger, Matthias A.“…While this represents a huge milestone, it is unclear if human GLUT9 can benefit from this advancement through subsequent structural based targeting and mutagenesis. …”
Publicado 2014
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512“…We outline an ambitious 10-year roadmap for research in the “omics era,” and explore key milestones needed to accomplish the goal of delivering three new vaccines, antivirals and acaricides for TBF control by 2030.…”
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513“…Our comprehensive phylogenetic analysis sets a milestone for the scientific community, as we propose a new and simple nomenclature to correctly name SUT MST and SWEET families. …”
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514por Federico, Concetta, Bruno, Francesca, Ragusa, Denise, Clements, Craig S., Brancato, Desiree, Henry, Marianne P., Bridger, Joanna M., Tosi, Sabrina, Saccone, Salvatore“…SIMPLE SUMMARY: New methodologies and technologies developed in the last few decades have highlighted the precise spatial organization of the genome into the cell nucleus, with chromatin architecture playing a central role in controlling several genome functions. …”
Publicado 2021
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515por Federico, Alessio“…The LHCb experiment at the LHC has collected more than 1 fb$^{-1}$ of physics data during the first two years of operation at the LHC, reaching one of its most important milestones. This has allowed the experiment to already perform extensive world-class measurements in b and c-physics, in order to probe New Physics Beyond the Standard Model. …”
Publicado 2012
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516por Uetrecht, Max“…At the end, a brief outlook on unfinished milestones and a potential CouchDB 4 migration is given.…”
Publicado 2021
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517por Venturini Delsolaro, Walter, Bravin, Enrico, Delruelle, Nicolas, Elias, Michal, Fadakis, Eleftherios, Ferreira Somoza, Jose, Formenti, Fabio, Fraser, Matthew, Gayde, Jean-Christophe, Guillotin, Nicolas, Kadi, Yacine, Kautzmann, Guillaume, Koettig, Torsten, Leclercq, Yann, Martino, Michele, Mician, Matej, Miyazaki, Akira, Montesinos, Eric, Parma, Vittorio, Rodriguez, Jose, Sadovich, Sergey, Siesling, Erwin, Smekens, David, Therasse, Mathieu, Valdarno, Luca, Valuch, Daniel, Vandoni, Giovanna, Wagner, Udo, Zhang, Pei“…The HIE-ISOLDE project (High Intensity and Energy ISOLDE) reached an important milestone in October 2015 when the first physics run was carried out with radioactive Zn beams at 4 MV/m. …”
Publicado 2017
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518por Hardiman, Maxwell Charles“…In 2012, the world is approaching a major 5-year milestone in the global commitment to ensure national capacities to identify, investigate, assess, and respond to public health events. …”
Publicado 2012
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519por Colella, Domenico“…The ALICE ITS 3 project is planning to build a new vertex tracker based on truly cylindrical wafer-scale sensors, with <0.05% X/X$_{0}$ per layer and located as close as 18 mm to the interaction point. …”
Publicado 2021
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520“…Further work is needed to develop new tools or alter existing tools that can be adapted to diverse settings and cultures.…”
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