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981“…Communication between chloroplasts and the nucleus is one of the milestones of the evolution of plants on earth. Proteins encoded by ancestral chloroplast-endogenous genes were transferred to the nucleus during the endosymbiotic evolution and originated this communication, which is mainly dependent on specific transit-peptides. …”
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982por Chaisson, Eric J.“…Such evolution writ large has significant potential to unify the natural sciences into a holistic understanding of who we are and whence we came. No new science (beyond frontier, nonequilibrium thermodynamics) is needed to describe cosmic evolution's major milestones at a deep and empirical level. …”
Publicado 2014
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983por Walsh, Kieran“…Improvements to postgraduate training have included newly designed postgraduate curricula, new forms of delivery of learning, more valid and reliable assessments, and more rigorous evaluation of training programmes. …”
Publicado 2014
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984por Schollemann, Franziska, Barbosa Pereira, Carina, Rosenhain, Stefanie, Follmann, Andreas, Gremse, Felix, Kiessling, Fabian, Czaplik, Michael, Abreu de Souza, Mauren“…This is an important and successfully implemented milestone on the way to simulating the internal temperature profile. …”
Publicado 2021
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985“…However, the key psychological indicators or milestones that represent safe return to sports readiness remains poorly understood. …”
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986por Shah, Kiran, Shah, Nirali, Ghassemi, Fatameh, Ly, Carolyn, George, Teena, Lutz, Carla, Sumer, Huseyin“…Cellular therapies, deemed live medicine, have brought a wave of new generation biological therapies to treat previously untreatable diseases such as cancers and degenerative diseases like osteoarthritis. …”
Publicado 2022
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987por Glisic, Branko“…Current research focuses on a third generation of strain sensors for two-dimensional (2D) distributed and quasi-distributed sensing, based on new advanced technologies. On the occasion of strain sensing centenary, and as an homage to all researchers, practitioners, and educators who contributed to strain-based SHM, this paper presents an overview of the first one hundred years of strain sensing technological progress, with the objective to identify relevant transformative milestones and indicate possible future research directions.…”
Publicado 2022
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988“…Savvy’s experience may help investigators in designing new interventions, particularly online interventions or in considering augmentation or delivery platform change of established interventions.…”
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989“…Other effects include the potential for arrest in adolescent development, which can occur when there is disruption in expected developmental milestones. New cohorts of adolescents who may not otherwise initiate substances may now be at risk. …”
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990“…This study is likely to set the milestones of a new generation of nano-devices with dual electronic/thermoelectric functionalities.…”
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991“…Organelle acquisitions via endosymbioses with prokaryotes were milestones in the evolution of eukaryotes. Still, quite a few uncertainties have remained for the evolution in the early stage of organellogenesis. …”
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992por González-de la Fuente, Sandra, Peiró-Pastor, Ramón, Rastrojo, Alberto, Moreno, Javier, Carrasco-Ramiro, Fernando, Requena, Jose M., Aguado, Begoña“…Regarding the present L. infantum genome-draft, 495 new genes have been annotated, a hundred have been corrected and 75 previous annotated genes have been discontinued. …”
Publicado 2017
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993“…The proposed nanometrology method represents an important milestone and potentially opens up new possibilities to develop next-generation super-polished X-ray mirrors, which will advance the development of X-ray nanoprobes, coherence preservation, and astronomical physics.…”
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994por Mielgo-Rubio, Xabier, Cardeña Gutiérrez, Ana, Sotelo Peña, Verónica, Sánchez Becerra, Maria Virginia, González López, Andrea María, Rosero, Adriana, Trujillo-Reyes, Juan Carlos, Couñago, Felipe“…In 2020 and 2021, after more than a decade with no major advances or new drugs, two phase III clinical trials published results positioning immunotherapy as a promising option for the first- and second-line treatment of MPM. …”
Publicado 2022
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995por Liu, Hong‐Bin, Li, Xiaoxu, Cai, Jun, Jiang, Ling‐Li, Zhang, Xin, Wu, Dousheng, Wang, Lifeng, Yang, Aiguo, Guo, Cun, Chen, Jia, Pu, Wenxuan, Yu, Feng“…Our results will set a new milestone in the development of the plant RLK kinase regulation theory and provide a novel strategy for the prevention and control of plant soil‐borne diseases without growth penalties.…”
Publicado 2022
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996por Gai, Wenxian, Yang, Fan, Yuan, Liangdan, ul Haq, Saeed, Wang, Yaru, Wang, Ying, Shang, Lele, Li, Fangman, Ge, Pingfei, Dong, Haiqiang, Tao, Jinbao, Wang, Fei, Zhang, Xingyu, Zhang, Yuyang“…In this study, we carried out a genome-wide association study (GWAS) on MA using eight milestone models with two-environment repeats. A series of associated SNP variations were identified from the GWAS, and 15 high-confidence annotated genes were further predicted based on linkage disequilibrium and lead SNPs. …”
Publicado 2023
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997por Aravena, Carlos, Mehta, Atul C., Almeida, Francisco A., Lamb, Carla, Maldonado, Fabien, Gildea, Thomas R.“…Jean-François Dumon from France advanced the use of Nd-YAG laser in the endobronchial tree and created the dedicated Dumon silicone stent introducing the whole new field of interventional pulmonology (IP). This major milestone revitalized interest in rigid bronchoscopy (RB). …”
Publicado 2023
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998por Kioutchoukova, Ivelina P, Foster, Devon T, Thakkar, Rajvi N, Foreman, Marco A, Burgess, Brandon J, Toms, Rebecca M, Molina Valero, Eduardo E, Lucke-Wold, Brandon“…Emerging innovations and the role of genetic treatments open a new window of opportunity for the treatment of neurologic orphan diseases.…”
Publicado 2023
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999por Monge, Guadalupe, Jimenez-Espejo, Francisco J., García-Alix, Antonio, Martínez-Ruiz, Francisca, Mattielli, Nadine, Finlayson, Clive, Ohkouchi, Naohiko, Sánchez, Miguel Cortés, de Castro, Jose María Bermúdez, Blasco, Ruth, Rosell, Jordi, Carrión, José, Rodríguez-Vidal, Joaquín, Finlayson, Geraldine“…Homo species were exposed to a new biogeochemical environment when they began to occupy caves. …”
Publicado 2015
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1000por Jiang, Xiaofan, Ma, Zhongyuan, Xu, Jun, Chen, Kunji, Xu, Ling, Li, Wei, Huang, Xinfan, Feng, Duan“…The realization of ultra-low power Si-based resistive switching memory technology will be a milestone in the development of next generation non-volatile memory. …”
Publicado 2015
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