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  1. 1061
    “…To provide all countries with precise targets, new conceptual definitions are suggested to more precisely describe the old goals of "control" - here more exactly named "controlled low-endemic malaria" - and "elimination." …”
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    How absolute is zero? An evaluation of historical and current definitions of malaria elimination
  2. 1062
    “…Newborn TPH2−/− mutant mice show delays in the expression of key developmental milestones and their diminished preference for maternal scents over the scent of an unrelated female is a forerunner of more severe socialization deficits that emerge in weanlings and persist into adulthood. …”
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    Mice Genetically Depleted of Brain Serotonin Display Social Impairments, Communication Deficits and Repetitive Behaviors: Possible Relevance to Autism
  3. 1063
    “…This review highlights the increasing knowledge of the significance of PhoPR in the evolution of the MTBC and its potential application in the construction of new attenuated vaccines based on phoPR inactivation. …”
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    Evolutionary Landscape of the Mycobacterium tuberculosis Complex from the Viewpoint of PhoPR: Implications for Virulence Regulation and Application to Vaccine Development
  4. 1064
    “…Single-cell sequencing methods, currently powered by multiple displacement genome amplification (MDA), have passed important milestones such as finishing and closing the genome of a prokaryote. …”
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    Efficient Synergistic Single-Cell Genome Assembly
  5. 1065
    por Saeed, Naba, Gurakar, Ahmet
    Publicado 2016
    “…Formulation of effective interferon-free regimens is a huge milestone, and awareness needs to be raised regarding these new highly effective options in both the physician and the patient population. …”
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    Tackling HCV-3 in Asia: Breakthroughs for Efficient and Cost-effective Treatment Strategies
  6. 1066
    por Foletti, Alberto, Fais, Stefano
    Publicado 2019
    “…Actually, many recent studies support a step back in current strategies that could lead to new discoveries in science. This change should seriously consider the idea that to further focus research project milestones that are already too focused could be a mistake. …”
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    Unexpected Discoveries Should Be Reconsidered in Science—A Look to the Past?
  7. 1067
    “…Based on the experimental observations of this study, a new mechanism of the transesterification reaction occurring during reactive compounding of PC and PMMA in the presence of the effective catalysts is proposed.…”
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    Transparent PC/PMMA Blends Via Reactive Compatibilization in a Twin-Screw Extruder
  8. 1068
    “…Considering all these milestones, and paraphrasing Sir Isaac Newton, if hepatologists have seen further, it is by standing on the shoulders of giants. …”
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    Pathophysiology of Portal Hypertension
  9. 1069
    por Zeng, Shihong, Zhou, Ya
    Publicado 2021
    “…FDI has played a significant role in promoting Chinese economic development, and the FDI technology spillover effect is one of the core forces driving China towards reaching new growth milestones. Therefore, due to the country’s interest in development, there is competition for FDI throughout China. …”
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    Foreign Direct Investment’s Impact on China’s Economic Growth, Technological Innovation and Pollution
  10. 1070
    “…CONCLUSION: These findings provide a milestone to understand the cancer burden in the country for the first time using the PBCR and will be helpful to develop and prioritize cancer control strategies.…”
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    Epidemiologic Pattern of Cancer in Kathmandu Valley, Nepal: Findings of Population-Based Cancer Registry, 2018
  11. 1071
    “…Hematopoietic stem cell transplantation (HSCT) has been the gold standard therapy in ALL Ph+ patients, but recently first-generation tyrosine kinase inhibitor (TKI)-imatinib became a major milestone in increasing overall survival. Genomic analyses give the opportunity for the investigation of new fusions or mutations, which can be used to establish effective targeted therapies. …”
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    Genomic Analyses of Pediatric Acute Lymphoblastic Leukemia Ph+ and Ph-Like—Recent Progress in Treatment
  12. 1072
    “…With the rise of antibody-drug conjugates (ADCs), milestone progress was made in clinical research based on Dol-10. …”
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    Marine Antitumor Peptide Dolastatin 10: Biological Activity, Structural Modification and Synthetic Chemistry
  13. 1073
    “…As a matter of fact, the mealworm is the first edible insect to achieve this important milestone in the EU. Due to this new scientific opinion, considerable expectations arise on mealworms and their potential in different fields, which will surely lead to market developments in the following years. …”
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    Mealworm (Tenebrio molitor): Potential and Challenges to Promote Circular Economy
  14. 1074
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    Ocular manifestations in children with developmental delay at a tertiary center in South India
  15. 1075
    “…The plastic industry is undergoing drastic changes, due to the customer sustainability perception of plastics, and the eruption of new processes (such 3D printing) and materials (such as renewably sourced resins). …”
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    Development of a Multi-Criteria Design Optimization Methodology for Automotive Plastics Parts
  16. 1076
    “…Following this training, Fellows will provide tailored support to validated projects by establishing development milestones, liaising with industry experts, navigating regulatory requirements, and drafting marketing materials such as executive summaries and financial projections. …”
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    4328 Translational Fellows as a mechanism to improve throughput of university technology commercialization
  17. 1077
    “…The use of design space (DS) is a key milestone in the quality by design (QbD) of pharmaceutical processes. …”
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    Thermodynamic Balance vs. Computational Fluid Dynamics Approach for the Outlet Temperature Estimation of a Benchtop Spray Dryer
  18. 1078
    por Wei, Wei, Zhao, Yan
    Publicado 2022
    “…In addition, some important issues, especially those related to recognizing new ‘Candidatus Phytoplasma’ species, are discussed. …”
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    Phytoplasma Taxonomy: Nomenclature, Classification, and Identification
  19. 1079
    “…The MMW detection circuit demonstrated in this work was found to be a milestone to develop larger focal plane arrays (FPA) with very inexpensive sensor elements.…”
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    Fast and Enhanced MMW Imaging System Using a Simple Row Detector Circuit with GDDs as Sensor Elements and an FFT-Based Signal Acquisition System
  20. 1080
    “…We briefly summarize novel symptomatic drugs and highlight the key milestones of new techniques and therapeutic programs as they stand today which can offer highly promising disease-modifying interventions for genetic IDs accompanied by various challenges.…”
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    Promising therapeutic aspects in human genetic imprinting disorders
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