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  1. 1101
    “…The identification of tumor “oncogenic drivers” and the subsequent development of targeted therapy represented a milestone in the treatment of lung cancer over the last years. …”
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    Immuno-targeted combinations in oncogene-addicted non-small cell lung cancer
  2. 1102
    “…METHODS: The CBIT+TMS trial is a two-phase, milestone driven early-stage randomized controlled trial. …”
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    The CBIT+TMS Trial: study protocol for a two-phase randomized controlled trial testing neuromodulation to augment behavior therapy for youth with chronic tics
  3. 1103
    “…She has since remained in remission with age-appropriate developmental milestones over the past 2 years. ATRTs should be considered in the differential diagnosis of intradural spinal lesions, especially in the pediatric patient population. …”
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    Clinical diagnostic and radiographic features of primary spinal atypical teratoid rhabdoid tumors tumor in a pediatric patient: A case report and review of the literature
  4. 1104
    “…METHODS: Data from February to July of the years 2019, 2020 and 2021 were collected and three practical parameters of the trial unit were investigated: milestones, performance, and impact. RESULTS: The trials mean numbers were 18, 24, and 23, in 2019, 2020, and 2021 respectively. …”
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    A single experience in the conduction of clinical trial during COronaVIrusDisease-2019 pandemic
  5. 1105
    “…CONCLUSIONS: As EHRs and other supporting technologies evolve, medical educators should continue to look for new opportunities within the EHR for education. …”
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    Electronic Health Records as an Educational Tool: Viewpoint
  6. 1106
    “…In postcurriculum surveys, 87% (13/15) of respondents reported having learned something new, 92% (12/13) anticipated applying this knowledge to pathology practice, and 81% (13/16) would recommend it to a pathology trainee colleague. …”
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    Broadening Our Scope: A Pilot Curriculum in Bioethics for Pathology Graduate Medical Trainees, the Emory University Experience
  7. 1107
    “…BACKGROUND: Dramatic improvements in spinal muscular atrophy (SMA) treatment have changed the prognosis for patients with this disease, leading to important new questions. Gathering representative, real-world data about the long-term efficacy and safety of emerging SMA interventions is essential to document their impact on patients and caregivers. …”
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    RESTORE: A Prospective Multinational Registry of Patients with Genetically Confirmed Spinal Muscular Atrophy - Rationale and Study Design
  8. 1108
    “…In total, 98% of the gene models identified in v1.0 were mapped onto this new assembly through development of a dedicated approach implemented in the MAGAAT pipeline. …”
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    Optical maps refine the bread wheat Triticum aestivum cv. Chinese Spring genome assembly
  9. 1109
    “…In addition, the Ministry of Health prepared a new national plan for eliminating mother-to-child transmission of syphilis, with clear monitoring milestones. …”
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    WHO method for estimating congenital syphilis to inform surveillance and service provision, Paraguay
  10. 1110
    “…OBJECTIVE: The aim of this study was to identify effective vaccine candidates that can offer a new milestone in the battle against COVID-19. METHODS: We used a reverse vaccinology approach to explore the SARS-CoV-2 genome among strains prominent in India. …”
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    Identification of Potential Vaccine Candidates Against SARS-CoV-2 to Fight COVID-19: Reverse Vaccinology Approach
  11. 1111
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    Trends, Differentials, and Social Determinants of Maternal Health Care Services Utilization in Rural India: An Analysis from Pooled Data
  12. 1112
    “…Founded in late 2015, the milestone GENIE 9.1-public release contains data from >110,000 tumors from >100,000 people treated at 19 cancer centers from the United States, Canada, the United Kingdom, France, the Netherlands, and Spain. …”
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    AACR Project GENIE: 100,000 Cases and Beyond
  13. 1113
    “…Our research shows that talar plasticity, even though genetically driven, may show mechanical influences and contribute to tracking the main locomotor milestones.…”
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    Human talar ontogeny: Insights from morphological and trabecular changes during postnatal growth
  14. 1114
    “…INTRODUCTION: Treatment Resistant Depression (TRD) occurs in up to 30% of patients with Major Depressive Disorder (MDD). New treatments are clearly needed and there is a burgeoning interest in novel agents including ketamine. …”
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    A 28-Day, Randomized, Controlled, Single-Blind, Phase 2 Study in Treatment-Resistant Major Depressive Disorder (TRD) Patients Receiving Intranasal Esketamine Comparing Addition of Almond Therapy TM with Treatment-as-Usual (TAU)
  15. 1115
    “…Here we describe network initiatives, early accomplishments, and future milestones.…”
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    Bridging the gap to advance the care of individuals with cancer: collaboration and partnership in the Cardiology Oncology Innovation Network (COIN)
  16. 1116
    “…These adversities disrupt the normative developmental milestones and can gravely compromise their health and emotional wellbeing. …”
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    Bridges-Round 2: A study protocol to examine the longitudinal HIV risk prevention and care continuum outcomes among orphaned youth transitioning to young adulthood
  17. 1117
    “…The RBE values were also calculated with a new abridged microdosimetric distribution methodology (AMDM) and compared with the reference RBE calculations using the entire distributions. …”
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    A methodology to abridge microdosimetric distributions without a significant loss of the spectral information needed for the RBE computation in carbon ion therapy
  18. 1118
    “…Affected individuals meet early milestones before neurological deterioration and early death. …”
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    A retrospective cohort study of Libmeldy (atidarsagene autotemcel) for MLD: What we have accomplished and what opportunities lie ahead
  19. 1119
    “…Phenylpyrazolo[3,4-d]pyrimidine is considered a milestone scaffold known to possess various biological activities such as antiparasitic, antifungal, antimicrobial, and antiproliferative activities. …”
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    Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies
  20. 1120
    “…Nowadays, interleukin 28B genotyping is considered to be a key diagnostic tool for the management of HCV-infected patients and will maintain its significance for new combination treatment schemes using direct-acting antiviral agents and even in interferon-free regimens. …”
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    Clinical utility of pharmacogenomics in the management of hepatitis C
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