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  1. 1641
    “…RESULTS: Adiponectin level was independently associated with baseline total SHS (adjusted β = 0.12; P = 0.006). It was also associated with ∆SHS ≥1 (adjusted odds ratio (aOR) = 1.84 (1.25 to 2.72)) involving erosive as well as narrowing disease progression (aOR = 1.73 (1.17 to 2.55) and 1.93 (1.04 to 3.57), respectively). …”
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    Serum level of adiponectin is a surrogate independent biomarker of radiographic disease progression in early rheumatoid arthritis: results from the ESPOIR cohort
  2. 1642
    “…In addition, only rs1532269 yielded a suggestive association (P = 0.0033) with the response to TNFi when available data from previous studies were combined in the meta-analysis. …”
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    Lack of validation of genetic variants associated with anti–tumor necrosis factor therapy response in rheumatoid arthritis: a genome-wide association study replication and meta-analysis
  3. 1643
    “…RESULTS: Before starting the treatment, the percentage of iTNFα+ CD14+ cells in the RA patients was significantly lower than that in healthy donors (mean ± SEM = 33.16 ± 4.82% vs 66.51 ± 2.4%, P < 0.001). When we added in vitro TNFα to healthy donor culture cells, levels of iTNFα+ CD14+ cells decreased, suggesting that the TNFα signal was responsible for the iTNFα+ CD14+ cell downregulation observed in the RA patients. …”
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    Adalimumab regulates intracellular TNFα production in patients with rheumatoid arthritis
  4. 1644
    “…Young age at disease onset (<5 years old) and permanent PVDI scores ≥3 were significantly associated with mortality risk (P = 0.024). CONCLUSION: TA is a rare and potentially life-threatening large-vessel vasculitis. …”
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    Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom
  5. 1645
    “…METHODS: Athletes from the 2012-2013 and 2013-2014 National Football League (NFL) seasons were included in this analysis of publicly available data. …”
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    Concussion Incidence in Professional Football: Position-Specific Analysis With Use of a Novel Metric
  6. 1646
    “…Players treated non-operatively had no change in ERA, FIP, or WAR following injury but had a higher WHIP after injury (p=0.039). Players treated operatively had no change in any measured performance metrics following surgery. …”
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    Performance and Return to Sport Following Latissimus Dorsi and Teres Major Injuries in Professional Baseball Pitchers
  7. 1647
    “…A case of epilepsy was defined according to the 2014 International League Against Epilepsy (ILAE) guidelines. Exposure to O. volvulus was assessed by testing for IgG4 antibodies to an O. volvulus antigen (OV16 Rapid Test,) in individuals aged 3 years and older. …”
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    High prevalence of epilepsy in onchocerciasis endemic health areas in Democratic Republic of the Congo
  8. 1648
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    Antiepileptic drug therapy in autoimmune epilepsy associated with antibodies targeting the leucine‐rich glioma‐inactivated protein 1
  9. 1649
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    Adjunctive levetiracetam in the treatment of Chinese and Japanese adults with generalized tonic–clonic seizures: A double‐blind, randomized, placebo‐controlled trial
  10. 1650
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    Diagnostic implications of genetic copy number variation in epilepsy plus
  11. 1651
    “…The UroMuTERT sensitivity was (i) highest for urinary cfDNA and cellDNA combined, (ii) consistent across primary and recurrent cases, tumour stages and grades, (iii) higher for low-risk non-muscle invasive UC (86·1%) than urine cytology (23·0%) (P < 0·0001) and (iv) 93·9% when combined with cytology. …”
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    Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer
  12. 1652
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    Time to onset of cannabidiol (CBD) treatment effect in Lennox–Gastaut syndrome: Analysis from two randomized controlled trials
  13. 1653
    “…The first symptoms of antineutrophil cytoplasmic antibody-associated vasculitis had started 5 years earlier with palpable purpura in the lower limbs, hemoptysis, and positive perinuclear (p)-antibody-associated vasculitis level (> 300 AU/mL). …”
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    Glomerulonephritis associated with systemic sclerosis: a case report
  14. 1654
    “…The number of swollen joints, tender joints, ESR and DAS-28 were more in the high activity group with the p-value of (0.018, 0.001, < 0.003 and < 0.004), respectively. …”
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    Non-contact meibography changes according to disease activity in rheumatoid arthritis cases
  15. 1655
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    Neuronal antibodies in pediatric epilepsy: Clinical features and long‐term outcomes of a historical cohort not treated with immunotherapy
  16. 1656
    “…These rates were significantly higher in patients naïve to biologic agents as compared to patients pre-exposed to biologics (LDA: naïve 100% 92 d, pre-exposed 57.0% 434 d, p ≤ 0.001; remission: naïve 86.7% 132 d, pre-exposed 44.1%, 692 d, p = 0.001). …”
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    Effectiveness, Tolerability, and Safety of Tofacitinib in Rheumatoid Arthritis: A Retrospective Analysis of Real-World Data from the St. Gallen and Aarau Cohorts
  17. 1657
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    Tofacitinib in the treatment of Indian patients with rheumatoid arthritis: A post hoc analysis of efficacy and safety in Phase 3 and long‐term extension studies over 7 years
  18. 1658
    “…Patients with skeletal muscle oedema had higher T2-mapping times; there was a significant association between subjective assessments of muscle oedema and T2-mapping time (coef 2.46, p = 0.02) and percentage fat fraction (coef 3.41, p = 0.02). …”
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    Using magnetic resonance imaging to map the hidden burden of muscle involvement in systemic sclerosis
  19. 1659
    “…The instructional video group delivered significantly higher radiant exposure values (p=0.021) when light-curing the anterior tooth than the posterior. …”
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    Skill Retention of Light-Curing Technique Using Only Verbal Instructions versus Using an Instructional Video: A 2-Year Follow-Up Study of Dental Students
  20. 1660
    por Fallah, Aria, Lewis, Evan, Ibrahim, George M., Kola, Olivia, Tseng, Chi‐Hong, Harris, William B., Chen, Jia‐Shu, Lin, Kao‐Min, Cai, Li‐Xin, Liu, Qing‐Zhu, Lin, Jiu‐Luan, Zhou, Wen‐Jing, Mathern, Gary W., Smyth, Matthew D., O'Neill, Brent R., Dudley, Roy W. R., Ragheb, John, Bhatia, Sanjiv, Delev, Daniel, Ramantani, Georgia, Zentner, Josef, Wang, Anthony C., Dorfer, Christian, Feucht, Martha, Czech, Thomas, Bollo, Robert J., Issabekov, Galymzhan, Zhu, Hongwei, Connolly, Mary, Steinbok, Paul, Zhang, Jian‐Guo, Zhang, Kai, Hidalgo, Eveline Teresa, Weiner, Howard L., Wong‐Kisiel, Lily, Lapalme‐Remis, Samuel, Tripathi, Manjari, Sarat Chandra, Poodipedi, Hader, Walter, Wang, Feng‐Peng, Yao, Yi, Champagne, Pierre‐Olivier, Brunette‐Clément, Tristan, Guo, Qiang, Li, Shao‐Chun, Budke, Marcelo, Pérez‐Jiménez, Maria Angeles, Raftopoulos, Christian, Finet, Patrice, Michel, Pauline, Schaller, Karl, Stienen, Martin N., Baro, Valentina, Cantillano Malone, Christian, Pociecha, Juan, Chamorro, Noelia, Muro, Valeria L., von Lehe, Marec, Vieker, Silvia, Oluigbo, Chima, Gaillard, William D., Al‐Khateeb, Mashael, Al Otaibi, Faisal, Krayenbühl, Niklaus, Bolton, Jeffrey, Pearl, Phillip L., Weil, Alexander G.
    Publicado 2021
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    Comparison of the real‐world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug‐resistant epilepsy: A post hoc analysis of the HOPS study
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