Serotonin receptor 4 in the hippocampus modulates mood and anxiety

por Karayol, Remzi, Medrihan, Lucian, Warner-Schmidt, Jennifer L., Fait, Ben W., Rao, Meghana N., Holzner, Eva B., Greengard, Paul, Heintz, Nathaniel, Schmidt, Eric F.
Publicado 2021

Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition

por Musante, Veronica, Li, Lu, Kanyo, Jean, Lam, Tukiet T, Colangelo, Christopher M, Cheng, Shuk Kei, Brody, A Harrison, Greengard, Paul, Le Novère, Nicolas, Nairn, Angus C
Publicado 2017

Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia

por Ledo, Jose Henrique, Liebmann, Thomas, Zhang, Ran, Chang, Jerry C., Azevedo, Estefania P., Wong, Eitan, Silva, Hernandez Moura, Troyanskaya, Olga G., Bustos, Victor, Greengard, Paul
Publicado 2020

Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain

por Graves, Steven M., Xie, Zhong, Stout, Kristen A., Zampese, Enrico, Burbulla, Lena F., Shih, Jean C., Kondapalli, Jyothisri, Patriarchi, Tomasso, Tian, Lin, Brichta, Lars, Greengard, Paul, Krainc, Dimitri, Schumacker, Paul T., Surmeier, D. James
Publicado 2019

APP intracellular domain/WAVE1 pathway reduces amyloid β production

por Ceglia, Ilaria, Reitz, Christiane, Gresack, Jodi, Ahn, Jung-Hyuck, Bustos, Victor, Bleck, Marina, Zhang, Xiaozhu, Martin, Grant, Simon, Sanford M., Nairn, Angus C., Greengard, Paul, Kim, Yong
Publicado 2015

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

por Fieblinger, Tim, Graves, Steven M., Sebel, Luke E., Alcacer, Cristina, Plotkin, Joshua L., Gertler, Tracy S., Chan, C. Savio, Heiman, Myriam, Greengard, Paul, Cenci, M. Angela, Surmeier, D. James
Publicado 2014

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

por Engmann, Olivia, Giralt, Albert, Gervasi, Nicolas, Marion-Poll, Lucile, Gasmi, Laila, Filhol, Odile, Picciotto, Marina R., Gilligan, Diana, Greengard, Paul, Nairn, Angus C., Hervé, Denis, Girault, Jean-Antoine
Publicado 2015

Identification of Neurodegenerative Factors Using Translatome-Regulatory Network Analysis

por Brichta, Lars, Shin, William, Jackson-Lewis, Vernice, Blesa, Javier, Yap, Ee-Lynn, Walker, Zachary, Zhang, Jack, Roussarie, Jean-Pierre, Alvarez, Mariano J., Califano, Andrea, Przedborski, Serge, Greengard, Paul
Publicado 2015

Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements

por Pirhaji, Leila, Milani, Pamela, Dalin, Simona, Wassie, Brook T., Dunn, Denise E., Fenster, Robert J., Avila-Pacheco, Julian, Greengard, Paul, Clish, Clary B., Heiman, Myriam, Lo, Donald C., Fraenkel, Ernest
Publicado 2017

Obligatory roles of dopamine D1 receptors in the dentate gyrus in antidepressant actions of a selective serotonin reuptake inhibitor, fluoxetine

por Shuto, Takahide, Kuroiwa, Mahomi, Sotogaku, Naoki, Kawahara, Yukie, Oh, Yong-Seok, Jang, Jin-Hyeok, Shin, Chang-Hoon, Ohnishi, Yoshinori N., Hanada, Yuuki, Miyakawa, Tsuyoshi, Kim, Yong, Greengard, Paul, Nishi, Akinori
Publicado 2018

Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons

por Sargin, Derya, Chottekalapanda, Revathy U., Perit, Kristina E., Yao, Victoria, Chu, Duong, Sparks, Daniel W., Kalik, Salina, Power, Saige K., Troyanskaya, Olga G., Schmidt, Eric F., Greengard, Paul, Lambe, Evelyn K.
Publicado 2019

DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons

por Marion-Poll, Lucile, Roussarie, Jean-Pierre, Taing, Lieng, Dard-Dascot, Cloelia, Servant, Nicolas, Jaszczyszyn, Yan, Jordi, Emmanuelle, Mulugeta, Eskeatnaf, Hervé, Denis, Bourc’his, Déborah, Greengard, Paul, Thermes, Claude, Girault, Jean-Antoine
Publicado 2022

Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior

por Jin, Junghee, Bhatti, Dionnet L., Lee, Ko-Woon, Medrihan, Lucian, Cheng, Jia, Wei, Jing, Zhong, Ping, Yan, Zhen, Kooiker, Cassandra, Song, Claire, Ahn, Jung-Hyuck, Obermair, Gerald J., Lee, Amy, Gresack, Jodi, Greengard, Paul, Kim, Yong
Publicado 2019

GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease

por Xu, Peng, Chang, Jerry C., Zhou, Xiaopu, Wang, Wei, Bamkole, Michael, Wong, Eitan, Bettayeb, Karima, Jiang, Lu-Lin, Huang, Timothy, Luo, Wenjie, Xu, Huaxi, Nairn, Angus C., Flajolet, Marc, Ip, Nancy Y., Li, Yue-Ming, Greengard, Paul
Publicado 2021

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

por Xu, Jian, Chatterjee, Manavi, Baguley, Tyler D., Brouillette, Jonathan, Kurup, Pradeep, Ghosh, Debolina, Kanyo, Jean, Zhang, Yang, Seyb, Kathleen, Ononenyi, Chimezie, Foscue, Ethan, Anderson, George M., Gresack, Jodi, Cuny, Gregory D., Glicksman, Marcie A., Greengard, Paul, Lam, TuKiet T., Tautz, Lutz, Nairn, Angus C., Ellman, Jonathan A., Lombroso, Paul J.
Publicado 2014

The role of ventral striatal cAMP signaling in stress-induced behaviors

por Plattner, Florian, Hayashi, Kanehiro, Hernandez, Adan, Benavides, David R., Tassin, Tara C., Tan, Chunfeng, Day, Jonathan, Fina, Maggy W., Yuen, Eunice Y., Yan, Zhen, Goldberg, Matthew S., Nairn, Angus C., Greengard, Paul, Nestler, Eric J., Taussig, Ronald, Nishi, Akinori, Houslay, Miles D., Bibb, James A.
Publicado 2015

Innate immunity protein IFITM3 modulates γ-secretase in Alzheimer disease

por Hur, Ji-Yeun, Frost, Georgia R., Wu, Xianzhong, Crump, Christina, Pan, Si Jia, Wong, Eitan, Barros, Marilia, Li, Thomas, Nie, Pengju, Zhai, Yujia, Wang, Jen Chyong, TCW, Julia, Guo, Lei, McKenzie, Andrew, Ming, Chen, Zhou, Xianxiao, Wang, Minghui, Sagi, Yotam, Renton, Alan E., Esposito, Bianca T., Kim, Yong, Sadleir, Katherine R., Trinh, Ivy, Rissman, Robert A., Vassar, Robert, Zhang, Bin, Johnson, Douglas S., Masliah, Eliezer, Greengard, Paul, Goate, Alison, Li, Yue-Ming
Publicado 2020