“…Background: In T4DM (men aged 50 – 74 yrs., waist circumference (WC) ≥95cm cm, prediabetes, or newly diagnosed type 2 diabetes (T2D) and serum testosterone (T) ≤ 14 nmol/L), 2 years treatment with T-undecanoate (1000 mg IM 3 monthly) vs placebo while enrolled in a lifestyle weight management program, decreased fat mass, and reduced the risk of T2D by 40%. …”
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“…Methods: This is a secondary analysis of a pooled cohort of 60 obese adolescents with and without PCOS, enrolled in 1 of three studies (NCT02157974; NCT03041129; NCT03717935) at the University of Colorado, Anschutz. …”
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“…Legs length was obtained by subtracting sitting height from stature; U/L was calculated dividing sitting height for legs length.RESULTS: A total of 70 CHH and 45 KS age-matched patients were enrolled (mean age 33.7±13.7 and 35.3±13.7 years, respectively). …”
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“…Medical records of 25 patients diagnosed with type 2 DM and 66 patients with acute leukemia were investigated for serum glycated albumin, HbA1c, fasting blood glucose level, and demographic data such as sex, age, height, weight and BMI z-scores. 115 children and adolescents who visited our outpatient center for routine child health examination were enrolled as the control group. Results: The median serum glycated albumin levels were 12.4%, 19.1% for acute leukemia and T2DM patients. …”
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“…Patients undergoing surgery at our institution between 2013-2020, who agreed to participate in the OncoPanel initiative and who had samples with good quality DNA were enrolled. Classification of PA into subtypes was performed by combining clinical and histopathological data. …”
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“…Methods: Eligible patients included women ≥ 55 years, diagnosed with Stage 0-IIIA breast cancer in the past 15 years, who had completed chemotherapy and/or were prescribed hormonal therapy, had pre-existing T2DM treated with ≥ 1 oral medication, and had been enrolled in an ongoing study of disease beliefs and cognition in breast cancer survivors with comorbid T2DM. …”
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“…CARDIA is a population-based multi-center study that enrolled Black and White participants beginning in 1985-1986. …”
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“…METHODS: Data from 85 participants enrolled in a randomized controlled trial and who had a research visit after 6 ± 1 months of follow-up were analyzed using univariate and multiple linear regressions (intervention, IG = 42; control, CG = 43). …”
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“…The neutral energy availability diet (NEA, 45 kCal/kg*LBM/d, ±0%) was followed by a deficient energy availability (DEA, -55%) intervention. On enrollment, we administered the following questionnaires: almost perfect, perceived stress, dysfunctional attitude, eating attitudes, exercise (IPAQ), appetite, and palatability. …”
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“…Among them, 159,798 women who also took the NHSE 2 years before the index checkup (baseline checkup) were enrolled for the study. Women with previous overt DM (n=11,852) or missing data (n=10,316) were excluded. …”
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“…Methods: 200 treatment-naïve prepubertal children with GHD were enrolled into REAL4, a randomised, multinational, open-labelled, and active-controlled phase 3 trial. 128 consented to a baseline blood transcriptome profile. …”
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“…RESULTS: A total of 125 enrolled patients (59 females; 66 males; median age 52) were grouped in LVC (67 patients, 54%) and HVC (58 patients, 46 %) groups according to neurosurgical centre expertise. …”
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“…Individuals were required to be continuously enrolled for ≥6 months pre- and ≥12 months post-index for baseline and follow-up assessments. …”
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“…Sixteen patients had variants of uncertain significance (VUS); in one of these cases, in silico prediction suggesting that the detected SH2B variant could be pathogenic has enabled enrollment in a Phase 2 study with setmelanotide. For other identified VUS, we are undertaking functional and biological studies using our novel translational platform, which was established to contribute evidence for possible variant reclassification. …”
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“…She fortunately recovered with mild deficits. She enrolled in an open-label randomized study- SATURN- which aims to assess safety of statin use in recurrent ICH. …”
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“…Methods: In total, 140 postmenopausal women with osteoporosis of the lumbar spine, followed at the Unit on Clinical and Translational Research in Endocrinology, University of Athens, Athens, Greece, were enrolled. They were divided into 2 groups. Group A (GA) included 70 women who were treated with Osteostrong (mean age: 57,7 y, 95% CI 54, 9-60,6 y); Group B (GB) included 70 women who had no exercise intervention (mean age 59,2 y, 95% CI 55,6-61,9 y). …”
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“…The patient underwent transsphenoidal resection, during which the neurosurgeon identified a suprasellar cystic lesion with classic epidermoid pearl white material. The lesion and capsule were resected, and patient started on dexamethasone 6 mg IV every 6 hours to prevent chemical meningitis. …”
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“…Methods: A total of 162 adult CAH patients with CAH were enrolled in this prospective, multi-centre study. Data was collected using a patient diary with the following aspects being assessed: frequency, cause, duration and dosage of dose adjustments and the occurrence of AC. …”
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“…This hypothesis was addressed using genetic and metabolomic analyses performed with fasting and 1-hr serum samples from a large multinational, multi-ancestry cohort of women enrolled in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study who underwent an oral glucose-tolerance test at ∼28 weeks’ gestation. …”
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“…Nearly half (48%) of all enrolled caregivers reported experiencing mild-to-moderate distress (CPDI score=28-51), and 15.7% felt severe distress (CPDI score >51) while seeking treatment for the non-COVID-19 illness of their patient. …”
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