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159961por Lim, Lee Ling, Lee, Heung Man, Lau, Eric, Luk, Andrea, Chow, Elaine, Ma, Ronald, Chan, Juliana, Kong, Alice“…We measured serum total BCAA in 2607 patients who were cancer-free at baseline and with available stored serum samples, who subsequently developed cancer after one year of enrolment into the HKDR. We performed Cox proportional hazards models with serum BCAA as the predictor variable, adjusting for age, sex, duration of T2D, cardiovascular risk factors (HbA(1c), systolic blood pressure, LDL-cholesterol, triglyceride and body mass index) and drug usage. …”
Publicado 2019
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159962por Kaviya, Arpeat, O'Reilly, Terry, Batonga, Joelle, Seki, Akiteru, Beale, Dominic, Yoneda, Kazuhiro, Bruce, Mark“…Methods: This First in Human study includes a double-blind, randomized, placebo-controlled, single ascending dose (SAD) part (including an assessment of food effect) in healthy adult male and female volunteers, 18-55 years of age. 34 males and 14 females were enrolled. Subjects were randomised to ONO-5788 or placebo (6:2 ratio) in each cohort with escalating doses of ONO-5788 (0.4, 1.6, 5, 20, 50 or 120mg) assessed. …”
Publicado 2019
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159963por Jung, Hyein, Ku, Cheol Ryong, Kim, Daham, Moon, Ju Hyung, Kim, Euihyun, Kim, Sun Ho, Lee, Eun-Jig“…There was no significant difference in tumor size and Hardy classification between biochemically controlled group and non-controlled group. Among the enrolled patients, 34 subjects (52.3%) had a size reduction of more than 10%. …”
Publicado 2019
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159964por Fa, Alice, Maher, James, Ghandi, Kushal, Esquivel, Esteban, Gudenkauf, Brent, ALPADI, KANNAN, Shreyder, Katherine, Schlabritz-Lutsevich, Natalia“…This was a prospective observational study, patients were enrolled during first trimester of pregnancy according to the IRB-approved protocol (L#17-136): obese (OB, BMI ≥ 30 kg/m(2), n=13) and non-obese (nOB, BMI<30 kg/m(2) , n=14). …”
Publicado 2019
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159965por Delivanis, Danae“…Methods: Patients were prospectively enrolled from the adrenal clinics between 2014 and 2018. …”
Publicado 2019
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159966por Wittert, Gary, Gyawali, Prabin, Martin, Sean, Heilbronn, Leonie, Vincent, Andrew, Jenkins, Alicia, Januszewski, Andrzej, Taylor, Anne, Adams, Robert, Reynolds, Amy, O’Loughlin, Peter“…Methods: Participants were aged 35 years and over at enrolment (n=2563) and followed for an average of 4.95 years. …”
Publicado 2019
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159967OR19-6 A Novel Anti-CD40 Monoclonal Antibody, Iscalimab, Successfully Treats Graves’ Hyperthyroidismpor Kahaly, George, Stan, Marius, Gergely, Peter, Colin, Laurence, Amer, Ahmed, Schuhmann, Imelda, Espie, Pascal, Rush, James, Basson, Craig, He, YanLing“…Methods: In total, fifteen patients with Graves’ hyperthyroidism were enrolled in an open label Phase I proof-of concept study and all completed the trial. …”
Publicado 2019
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159968por De Vincentis, Sara, Decaroli, Maria Chiara, Diazzi, Chiara, Morini, Fabio, Bertani, Davide, Fanelli, Flaminia, Mezzullo, Marco, Santi, Daniele, Baraldi, Enrica, Tagliavini, Simonetta, Pagotto, Uberto, Guaraldi, Giovanni, Rochira, Vincenzo“…RESULTS: 315 consecutive HIV-infected men were enrolled (mean age 45.56±5.61 years; average duration of HIV-infection 16.57±10.45 years). …”
Publicado 2019
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159969por Whyte, Michael, Bishop, Nick, Hasan, Jawad, Hofmann, Christine, Högler, Wolfgang, Rockman-Greenberg, Cheryl, Sena, Veruska, Zhou, Shanggen, Kishnani, Priya“…In total, data were available for 112 patients (median [min, max] age at enrollment: 3.2 [0, 66.5] y; female: 51%; white: 84%). …”
Publicado 2019
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159970por Minneci, Peter C., Cooper, Jennifer N., Leonhart, Karen, Nacion, Kristine, Sulkowski, Jason, Porter, Kyle, Wei, Lai, Deans, Katherine J.“…Two hundred of 236 eligible children and adolescents aged 7 to 17 years with uncomplicated appendicitis enrolled with their caregivers. After receiving the randomized clinical intervention, caregivers chose surgery or nonoperative management. …”
Publicado 2019
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159971por Resende, Uanderson, Cabello, César, Ramalho, Susana Oliveira Botelho, Zeferino, Luiz Carlos“…RESULTS: Among the 310 women enrolled, 267 patients (86.2%) had non-pCR carcinoma presenting size T3/T4 (63.3%), node-positive axilla (74.9%), stage III (62.9%), Ki-67 ≥ 20% (71.9%) and non-luminal A (78.3%). …”
Publicado 2019
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159972por Rodger, Alison J, Cambiano, Valentina, Bruun, Tina, Vernazza, Pietro, Collins, Simon, Degen, Olaf, Corbelli, Giulio Maria, Estrada, Vicente, Geretti, Anna Maria, Beloukas, Apostolos, Raben, Dorthe, Coll, Pep, Antinori, Andrea, Nwokolo, Nneka, Rieger, Armin, Prins, Jan M, Blaxhult, Anders, Weber, Rainer, Van Eeden, Arne, Brockmeyer, Norbert H, Clarke, Amanda, del Romero Guerrero, Jorge, Raffi, Francois, Bogner, Johannes R, Wandeler, Gilles, Gerstoft, Jan, Gutiérrez, Felix, Brinkman, Kees, Kitchen, Maria, Ostergaard, Lars, Leon, Agathe, Ristola, Matti, Jessen, Heiko, Stellbrink, Hans-Jürgen, Phillips, Andrew N, Lundgren, Jens“…FINDINGS: Between Sept 15, 2010, and July 31, 2017, 972 gay couples were enrolled, of which 782 provided 1593 eligible couple-years of follow-up with a median follow-up of 2·0 years (IQR 1·1–3·5). …”
Publicado 2019
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159973por Feldman, Sergey, Ammar, Waleed, Lo, Kyle, Trepman, Elly, van Zuylen, Madeleine, Etzioni, Oren“…OBJECTIVE: To perform a large-scale analysis of global enrollment sex bias in clinical studies. DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional study, clinical studies from published articles from PubMed from 1966 to 2018 and records from Aggregate Analysis of ClinicalTrials.gov from 1999 to 2018 were identified. …”
Publicado 2019
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159974por Liu, Mei-Yan, Yang, Ya, Zhang, Li-Jun, Pu, Li-Hong, He, Dong-Fang, Liu, Jian-Yang, Hafeez, Adam, Ding, Yu-Chuan, Ma, Huan, Geng, Qing-Shan“…METHODS: This study enrolled 82 patients with documented CAD between June 1, 2017 and November 9, 2017. …”
Publicado 2019
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159975por Blancher, Marc, Maignan, Maxime, Clapé, Cyrielle, Quesada, Jean-Louis, Collomb-Muret, Roselyne, Albasini, François, Ageron, François-Xavier, Fey, Stephanie, Wuyts, Audrey, Banihachemi, Jean-Jacques, Bertrand, Barthelemy, Lehmann, Audrey, Bollart, Claire, Debaty, Guillaume, Briot, Raphaël, Viglino, Damien“…Among the 194 patients enrolled in the emergency department cohort between November 4, 2013, and April 10, 2016, 157 were randomized, and the protocol was correctly administered in 136 (69 IVM group, 67 INS group, per protocol population, 76% men, median age 40 [IQR 29 to 54] years). …”
Publicado 2019
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159976por van Dyck, Christopher H., Nygaard, Haakon B., Chen, Kewei, Donohue, Michael C., Raman, Rema, Rissman, Robert A., Brewer, James B., Koeppe, Robert A., Chow, Tiffany W., Rafii, Michael S., Gessert, Devon, Choi, Jiyoon, Turner, R. Scott, Kaye, Jeffrey A., Gale, Seth A., Reiman, Eric M., Aisen, Paul S., Strittmatter, Stephen M.“…DESIGN, SETTING, AND PARTICIPANTS: This multicenter phase 2a randomized clinical trial enrolled participants between December 23, 2014, and November 30, 2016. …”
Publicado 2019
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159977por Hanson, Claudia, Singh, Samiksha, Zamboni, Karen, Tyagi, Mukta, Chamarty, Swecha, Shukla, Rajan, Schellenberg, Joanna“…We aimed to assess care practices, causes of admission, and outcomes from neonatal intensive care units (NICUs) in public secondary and private tertiary hospitals and both public and private medical colleges enrolled in a quality improvement collaborative in Telangana and Andhra Pradesh—2 Indian states with a respective population of 35 and 50 million. …”
Publicado 2019
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159978por Choi, Brian G, Dhawan, Tania, Metzger, Kelli, Marshall, Lorraine, Akbar, Awdah, Jain, Tushina, Young, Heather A, Katz, Richard J“…Repeat laboratory biomarkers were performed at 3 and 6 months. RESULTS: Enrolled participants had a mean age with SE of 56.6 (SD 1.7) for SOC and 57.2 (SD 1.8) for EXP; 65.3% of SOC and 56.9% of EXP were male, and 20.4% of SOC and 35.3% of EXP had coronary artery disease. …”
Publicado 2019
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159979por Kwan, Marilyn L., Miglioretti, Diana L., Marlow, Emily C., Aiello Bowles, E. J., Weinmann, Sheila, Cheng, Stephanie Y., Deosaransingh, Kamala A., Chavan, Prachi, Moy, Lisa M., Bolch, Wesley E., Duncan, James R., Greenlee, Robert T., Kushi, Lawrence H., Pole, Jason D., Rahm, Alanna K., Stout, Natasha K., Smith-Bindman, R.“…Participants included pregnant women who gave birth to a live neonate of at least 24 weeks’ gestation between January 1, 1996, and December 31, 2016, and who were enrolled in the health care system for the entire pregnancy. …”
Publicado 2019
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159980“…A total of 41 subjects were enrolled at two headache specialty clinics in the USA. …”
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