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160261por Elgebaly, Salwa A., Christenson, Robert H., Kandil, Hossam, Ibrahim, Mohsen, Rizk, Hussien, El-Khazragy, Nashwa, Rashed, Laila, Yacoub, Beshoy, Eldeeb, Heba, Ali, Mahmoud M., Kreutzer, Donald L.“…Methods: Serum gene expression levels of miR-137, miR-106b-5p and their corresponding molecular pathway network were measured blindly in 70 enrolled subjects using quantitative real time PCR (qPCR). …”
Publicado 2021
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160262“…METHODS: A total of 261 patients were finally enrolled in this study and randomly divided into training (n=182) and validation cohorts (n=79). …”
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160263por Dasa, Osama, Smith, Steven M., Howard, George, Cooper-DeHoff, Rhonda M., Gong, Yan, Handberg, Eileen, Pepine, Carl J.“…EXPOSURES: Visit-to-visit systolic BP (SBP) and diastolic BP variability during the first year of enrollment using 4 different BP variability measures: standard deviation, coefficient of variation, average real variability, and variability independent of the mean. …”
Publicado 2021
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160264por Blair, Cindy K, Harding, Elizabeth, Wiggins, Charles, Kang, Huining, Schwartz, Matthew, Tarnower, Amy, Du, Ruofei, Kinney, Anita Y“…Malfunction of the Jawbone trackers occurred in one-third of the intervention group, resulting in enrollment stopping at 54 rather than the initial goal of 60 participants. …”
Publicado 2021
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160265por Betts, Grace M., Lipsky, Leah M., Temmen, Chelsie D., Siega-Riz, Anna Maria, Faith, Myles S., Nansel, Tonja R.“…METHODS: Participants were enrolled at < 12 weeks gestation and followed through 1 year postpartum. …”
Publicado 2021
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160266por Chen, Jieling, Nelson, David R, Borra, Sujana, Liu, Yi, Maughn, Keshia, Fan, Ludi, Rey, Gabriel G, Pollom, Roy D, Hood, Robert C“…The study period was OCT2013-SEP2018 and patients were required to have continuous enrollment for ≥6 months pre- and ≥3 years post-index periods. …”
Publicado 2021
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160267por Haws, Robert, Clément, Karine, Dollfus, Hélène, Han, Joan C, Haqq, Andrea Maria, Martos-Moreno, Gabriel Angel, Mittleman, Robert, Stewart, Murray, Webster, Matt, Yanovski, Jack, Yuan, Guojun, Argente, Jesús“…Results: A total of 38 individuals with BBS (n=32) or AS (n=6) were enrolled. Five participants <12 years and 2 participants ≥12 years who discontinued before receiving active therapy were not included in the primary analysis. …”
Publicado 2021
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160268por Zhang, Catherine D, Singh, Sumitabh, Suresh, Malavika, Ebbehøj, Andreas Ladefoged, LeBrasseur, Nathan K, Khosla, Sundeep, Bancos, Irina“…Results: A total of 23 patients with MACS and 23 age and sex-matched referent subjects without cortisol excess were enrolled. The median age of diagnosis was 63 years (range, 51–81), and 26 (56%) were women. …”
Publicado 2021
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160269por Falcone, John N, Hurd, Maurice A, Kumar, Sonal, Yeung, Michele, Newberry, Carolyn, So, Marie Yanielle, Dakin, Gregory, Bellorin-Marin, Omar, Afaneh, Cheguevara, Hudgins, Lisa, Peña, Jessica, Goncalves, Marcus D“…This abstract reports a preliminary analysis of the results from the first 45 subjects enrolled. Fasting blood samples were collected from 31 subjects with NAFLD and 14 subjects with other metabolic diseases (‘Other’) and without radiologic evidence of NAFLD. …”
Publicado 2021
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160270por Sharma, Dolly, Deering, Kathleen L, Loustau, Patrick, Culler, Michael D, Allas, Soraya, Weiss, Blandine, Mitchell, Deborah M, Astolfi, Danette, Mannstadt, Michael“…The patient eligibility criteria for the surgery-based method included the presence of a procedure claim of either parathyroidectomy, complete or partial thyroidectomy, or neck dissection, followed by a HP diagnosis claim (6–15 months apart) with a subsequent second HP diagnosis claim at any time point, and with continuous enrollment for 15 months before the index date (the date of the first qualifying HP diagnosis claim) and ≥6 months after. …”
Publicado 2021
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160271por Dhingra, Om P, Bernstein, James, Barnes, Shaina D, VanLaanen, Hannah, Wadlington, Natasha, Chang, Jessica“…Methods: A Phase 3, randomized, multicenter, open-label, active-controlled trial, comparing SOV2012F1 (testosterone undecanoate capsules) (n=214) with AndroGel® (1.62% topical testosterone gel) (n=100) enrolled males aged 18 to 65 years with hypogonadism (serum total T levels ≤281 ng/dL). …”
Publicado 2021
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160272“…Methods: During the time period April and September 2020, 20 patients with T2D being discharged on multiple daily injections admitted to North Shore University Hospital were enrolled in this study. Exclusion criteria were those with adhesive allergy, CKD 4/5 or on dialysis and pregnant women. …”
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160273por Plachy, Lukas, Dusatkova, Petra, Maratova, Klara, Petruzelkova, Lenka, Kolouskova, Stanislava, Snajderova, Marta, Obermannova, Barbora, Zemkova, Dana, Sumnik, Zdenek, Lebl, Jan, Pruhova, Stepanka“…Methods: Out of 522 individuals treated in our center with GH from the indication of primary GH deficiency (GHD) or small for gestational age short stature (SGA-SS), 87 children with FSS fulfilled the inclusion criteria (pre-treatment height ≤-2 SD in both patient/their shorter parent, signed written informed consent) and were enrolled to the study. Next-generation sequencing was performed to search for variants in COL2A1, COL9A1, COL9A2, COL9A3, COL10A1, COL11A1 and COL11A2 genes. …”
Publicado 2021
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160274por Mirabelli, Maria, Chiefari, Eusebio, Quaresima, Paola, Visconti, Federica, Foti, Daniela, Brunetti, Antonio“…For this, 769 consecutive women in singleton pregnancies, subjected to both anomaly scan and GDM screening, were retrospectively enrolled at our Institution between Jan 2018-Feb 2020. …”
Publicado 2021
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160275por Loftus, Jane, Chen, Yong, Alvir, Jose Ma J, Chi, Lei, Dasgupta, Shibasish, Gupta, Anu, Wajnrajch, Michael P“…Four patient cohorts were identified (12, 24, 36, and 48 months of post-index continuous enrollment). The demographic and clinical profiles of children with pGHD treated with daily injections of somatropin who have good adherence and those with sub-optimal adherence were characterized. …”
Publicado 2021
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160276por Nieman, Lynnette K, Boscaro, Marco, Scaroni, Carla Maria, Deutschbein, Timo, Mezosi, Emese, Driessens, Natacha, Georgescu, Carmen Emanuela, Hubalewska-D, Alicja, Berker, Dilek, Jarzab, Barbara Maria, Maiter, Dominique M, Reincke, Martin, Loli, Paola, Zampetti, Benedetta, Atmaca, Ayşegül, Badiu, Corin P, Beckers, Albert M, Bolanowski, Marek, Cavagnini, Francesco, Unger, Nicole, Giordano, Roberta, Hanzu, Felicia Alexandra, Terzolo, Massimo, Bostnavaron, Martine, Toth, Miklos“…Methods: This single arm, open-label, multicenter, international trial enrolled 50 patients with CS who had three baseline 24 hours urine free cortisol (UFC) values at least 50% above the upper limit of normal (ULN=165 nmol/24h). …”
Publicado 2021
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160277por Safren, Steven A, Thomas, Beena, Biello, Katie B, Mayer, Kenneth H, Rawat, Shruta, Dange, Alpana, Bedoya, C Andres, Menon, Sunil, Anand, Vivek, Balu, Vinoth, O’Cleirigh, Conall, Klasko-Foster, Lynne, Baruah, Dicky, Swaminathan, Soumya, Mimiaga, Matthew J“…FINDINGS: Between Sept 4, 2015, and June 28, 2018, we enrolled 608 participants; 305 (50%) were assigned to the psychosocial intervention condition and 303 (50%) were assigned to the control condition. 510 (84%) of 608 men completed an assessment at 4 months after randomisation, 483 (79%) at 8 months, and 515 (85%) at 12 months. 512 (99%) of 515 men had STI data from the 12-month assessment. …”
Publicado 2021
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160278“…METHODS: In line with our power calculation, we will enroll 60 participants and randomly assign them to one of two parallel arms. …”
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160279por Sachpekidis, Christos, Kopp-Schneider, Annette, Pan, Leyun, Papamichail, Dimitrios, Haberkorn, Uwe, Hassel, Jessica C., Dimitrakopoulou-Strauss, Antonia“…METHODS: Twenty-five patients with stage IV melanoma, scheduled for treatment with PD-1 inhibitors, were enrolled in the study (pembrolizumab, n = 8 patients; nivolumab, n = 4 patients; nivolumab/ipilimumab, 13 patients). [(18)F]FDG PET/CT was performed before the start of treatment (baseline PET/CT) and after the initial two cycles of PD-1 blockade administration (interim PET/CT). …”
Publicado 2020
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160280por Nordh, Martina, Wahlund, Tove, Jolstedt, Maral, Sahlin, Hanna, Bjureberg, Johan, Ahlen, Johan, Lalouni, Maria, Salomonsson, Sigrid, Vigerland, Sarah, Lavner, Malin, Öst, Lars-Göran, Lenhard, Fabian, Hesser, Hugo, Mataix-Cols, David, Högström, Jens, Serlachius, Eva“…DESIGN, SETTING, AND PARTICIPANTS: This single-masked, superiority randomized clinical trial enrolled participants at a clinical research unit integrated within the child and adolescent mental health services in Stockholm, Sweden, from September 1, 2017, to October 31, 2018. …”
Publicado 2021
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