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  1. 160901
    “…TRIAL REGISTRATION: We registered the study on 6 April 2016 before enrolling the first patient in the trial at the German Clinical Trials Register (www.germanctr.de) with the identifier DRKS00010269. …”
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    Fitness and mobility training in patients with Intensive Care Unit-acquired muscle weakness (FITonICU): study protocol for a randomised controlled trial
  2. 160902
    “…We aimed to investigate the acute effects of co-trimoxazole at prophylactic dose on glucose metabolism in healthy adults. METHODS: We enrolled 20 healthy volunteers (15 males and 5 females) aged 23.0 (SD 2.0) years, with mean BMI of 22.3 (SD 3.6) Kg/m(2) with normal glucose tolerance, hepatic and renal function. …”
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    Acute glycaemic effects of co-trimoxazole at prophylactic dose in healthy adults
  3. 160903
    “…Seventy age- and sex-matched patients were enrolled in this study as the negative controls. All the patients' sera were analyzed for the anti-SmD1(83-119), anti-Sm, anti-U1-nRNP, anti-double-stranded DNA (dsDNA), anti-nucleosome, anti-SSA/Ro60, anti-SSA/Ro52, anti-SSB, anti-Scl-70, and anti-histone antibodies using the immunoblotting assay. …”
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    Evaluating Anti-SmD1-amino-acid 83-119 Peptide Reactivity in Children with Systemic Lupus Erythematosus and Other Immunological Diseases
  4. 160904
    “…METHODS: After IRB approval and written informed consent, 20 patients aged 18 to 85 years of age undergoing > 3 level anterior and posterior spine fusion surgery were enrolled in the study. Patients were followed throughout the operative procedure, and for 12 h postoperatively. …”
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    Microvascular response to transfusion in elective spine surgery
  5. 160905
    “…On linear regression analysis, baseline SBP was the only predictor of SBP change; participants with higher SBP at enrollment exhibited significantly greater improvements at one-month follow-up (β=–0.63, P<.001). …”
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    Text Messaging to Improve Hypertension Medication Adherence in African Americans From Primary Care and Emergency Department Settings: Results From Two Randomized Feasibility Studies
  6. 160906
    “…METHODS: The present study enrolled 112 and 76 Japanese patients with chronic hepatitis C virus genotype 1b infection who were treated with a 12-wk TVR-based or SMV-based triple therapy, respectively, followed by a dual therapy that included pegylated interferon α and ribavirin (RBV) for 12 wk. …”
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    Efficacy and safety of telaprevir- and simeprevir-based triple therapies for older patients with chronic hepatitis C
  7. 160907
    “…Recruitment outcomes were recorded as screened, eligible, consent not asked, refused, and enrolled. Patient engagement was recorded as follow-up outcomes: (1) attrition during short message service (SMS) text message intervention and (2) attrition during the 12-month follow-up period. …”
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    Factors Associated With Dropout During Recruitment and Follow-Up Periods of a mHealth-Based Randomized Controlled Trial for Mobile.Net to Encourage Treatment Adherence for People With Serious Mental Health Problems
  8. 160908
    “…A total of 115 children were enrolled in the current study; as sixty-five (65) children with beta thalassemia major aged 5–18 years, on regular blood transfusion regimen represented the patient group. …”
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    Premature atherosclerosis in children with beta-thalassemia major: New diagnostic marker
  9. 160909
    “…BACKGROUND: With the onset of prevention trials for individuals at high risk for Alzheimer disease, there is increasing need for accurate risk prediction to inform study design and enrollment, but available risk estimates are limited. …”
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    APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts
  10. 160910
    “…METHODS: Patients who underwent ACL reconstruction (Current Procedural Terminology (CPT) code 29888) between 2007 and 2014 were identified using the PearlDiver database. Demographic data including age and sex were obtained for this cohort. …”
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    Risk Factors for Revision or Contralateral ACL Reconstruction: The Value of Physical Therapy
  11. 160911
    “…To determine long-term impact, the protocol outlines enrolling selected participants in mutually exclusive longitudinal cohorts (HIV-positive, PrEP, CCT, and HIV-negative) followed by using mobile phone text messages (short message service, SMS) and in-person surveys to prospectively assess prevention method uptake, adherence, and risk compensation behaviors. …”
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    Gender-Specific Combination HIV Prevention for Youth in High-Burden Settings: The MP3 Youth Observational Pilot Study Protocol
  12. 160912
    “…FINDINGS: 22 participants were enrolled between Oct 23, 2015, and Jan 18, 2016. Five participants received 400 mg DSM265 and two participants received placebo 1 day before CHMI (cohort 1A), six participants received daily atovaquone-proguanil 1 day before CHMI (cohort 1B), and six participants received 400 mg DSM265 and two participants received placebo 7 days before CHMI (cohort 2). …”
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    DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection
  13. 160913
    “…METHODS: A total of 5 adult smokers were enrolled in a longitudinal parent study assessing how e-cigarette use affects cigarette use among e-cigarette–naïve smokers. …”
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    Comparison of Ecological Momentary Assessment Versus Direct Measurement of E-Cigarette Use With a Bluetooth-Enabled E-Cigarette: A Pilot Study
  14. 160914
    “…RESULTS: One hundred and seventy-four expressed interest, 92 were eligible and 65 enrolled. Using linear mixed effects models, the differences between groups on all secondary measures post-intervention and at follow-up were not significant. …”
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    Effect of exercising at minimum recommendations of the multiple sclerosis exercise guideline combined with structured education or attention control education – secondary results of the step it up randomised controlled trial
  15. 160915
    “…Name of registry: Effects of the integrated delivery system and payment system of community-based intervention on rural patients of chronic diseases in Qianjiang District, China Date of registration: Retrospectively registered 23 November 2014. Date of enrolment of the first participant to the trial: 5 July 2012…”
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    The effect of health literacy and self-management efficacy on the health-related quality of life of hypertensive patients in a western rural area of China: a cross-sectional study
  16. 160916
    “…METHODS: Participants with elevated systolic BP (SBP ≥140 mm Hg) and HbA1c (≥7%) failing antihypertensive (≥2 medications) and oral diabetes therapy were enrolled in this three-arm, 12-week, cluster-randomized study. …”
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    Effectiveness of Digital Medicines to Improve Clinical Outcomes in Patients with Uncontrolled Hypertension and Type 2 Diabetes: Prospective, Open-Label, Cluster-Randomized Pilot Clinical Trial
  17. 160917
    por Nguyen, Joseph, Rodeo, Scott A.
    Publicado 2017
    “…Chi-square tests were used to compare the proportion of patients who attained minimally clinically important difference (MCID) from 1 to 2 years. RESULTS: 1,037 enrolled patients underwent ACL reconstruction from 2010 to 2012 - 893 being primary procedures. …”
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    No Clinically Relevant Change Between 1 and 2 Year Outcomes Following ACL Reconstruction
  18. 160918
    “…RESULTS: A total of N =1,544 subjects (Female = 50%, Age =16.1+1.1 yrs.) enrolled in the study, competed in 2,843 athletic seasons and participated in 167,349 athletic exposures during the school year. …”
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    The Effect of Sport Specialization on Lower Extremity Injury Rates in High School Athletes
  19. 160919
    “…RESULTS: Of the 331 patients who enrolled themselves, 301 patients completed at least one questionnaire. …”
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    Adherence to Web-Based Self-Assessments in Long-Term Direct-to-Patient Research: Two-Year Study of Multiple Sclerosis Patients
  20. 160920
    “…METHODS: Two Chinese university student cohorts, including one with 300 unrelated subjects with high myopia and 308 emmetropic controls from Guangzhou and a second with 96 unrelated individuals with moderate to high myopia and 96 emmetropic controls of Chaoshanese origin in Guangzhou, were enrolled in this study. Two SNPs, rs6469937 and rs13382811, were selected for genotyping based on their reported associations with severe myopia. …”
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    Association and interaction of myopia with SNP markers rs13382811 and rs6469937 at ZFHX1B and SNTB1 in Han Chinese and European populations
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