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  1. 161081
    “…METHODS AND RESULTS: Ninety‐nine ARVC patients (median age, 40 years; 70.7% male) and 96 healthy controls (median age, 41 years; 62.5% male) were enrolled. The circulating levels of testosterone were measured by enzyme‐linked immunosorbent assays (ELISA). …”
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    Plasma testosterone and arrhythmic events in male patients with arrhythmogenic right ventricular cardiomyopathy
  2. 161082
    por Siemieniuk, Reed AC, Bartoszko, Jessica J, Zeraatkar, Dena, Kum, Elena, Qasim, Anila, Díaz Martinez, Juan Pablo, Izcovich, Ariel, Rochwerg, Bram, Lamontagne, Francois, Han, Mi Ah, Agarwal, Arnav, Agoritsas, Thomas, Azab, Maria, Bravo, Gonzalo, Chu, Derek K, Couban, Rachel, Cusano, Ellen, Devji, Tahira, Escamilla, Zaira, Foroutan, Farid, Gao, Ya, Ge, Long, Ghadimi, Maryam, Heels-Ansdell, Diane, Honarmand, Kimia, Hou, Liangying, Ibrahim, Sara, Khamis, Assem, Lam, Bonnie, Mansilla, Cristian, Loeb, Mark, Miroshnychenko, Anna, Marcucci, Maura, McLeod, Shelley L, Motaghi, Sharhzad, Murthy, Srinivas, Mustafa, Reem A, Pardo-Hernandez, Hector, Rada, Gabriel, Rizwan, Yamna, Saadat, Pakeezah, Switzer, Charlotte, Thabane, Lehana, Tomlinson, George, Vandvik, Per O, Vernooij, Robin WM, Viteri-García, Andrés, Wang, Ying, Yao, Liang, Zhao, Yunli, Guyatt, Gordon H, Brignardello-Petersen, Romina
    Publicado 2020
    “…RESULTS: 463 trials enrolling 166 581 patients were included; 267 (57.7%) trials and 89 814 (53.9%) patients are new from the previous iteration; 265 (57.2%) trials evaluating treatments with at least 100 patients or 20 events met the threshold for inclusion in the analyses. …”
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    Drug treatments for covid-19: living systematic review and network meta-analysis
  3. 161083
    “…We also measured the main outcomes for a full-scale RCT, namely, change in weight and physical activity at 6- and 12-month follow-ups, and secondary outcomes, including changes in the HbA(1c) level, blood pressure, waist circumference, waist-to-hip ratio, and lipid levels. RESULTS: We enrolled 200 participants: 98 were randomized to the intervention and 102 were randomized to the control group. …”
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    A Wearable Technology Delivering a Web-Based Diabetes Prevention Program to People at High Risk of Type 2 Diabetes: Randomized Controlled Trial
  4. 161084
    “…METHODS: Level of evidence 3 controlled study with prospectively-collected multicenter database from 7 centers. Enrolled patients that underwent isolated hip arthroscopy that reached 2-year minimum follow-up with iHOT-12 were assigned to Iliopsoas group defined as pre-operative diagnosis of iliopsoas tendonitis, internal snapping symptoms, intra-operative anteroinferior labral pathology (below 3 O’clock location) and/or preoperative psoas injection or the control group. …”
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    Iliopsoas pathology, treatment, and outcomes in patients undergoing hip arthroscopy for femoroacetabular impingement: Findings from the [redacted] study group
  5. 161085
    “…Methods: 49 patients treated with definitive chemoradiation for locally advanced HNSCC were enrolled in this trial and received longitudinal hypoxia PET imaging using fluorine-18 misonidazole ([(18)F]FMISO) at weeks 0, 2 and 5 during treatment. …”
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    Hypoxia dynamics on FMISO-PET in combination with PD-1/PD-L1 expression has an impact on the clinical outcome of patients with Head-and-neck Squamous Cell Carcinoma undergoing Chemoradiation
  6. 161086
    “…The study cohort comprised patients with ASCVD (ischemic heart disease, peripheral arterial disease, or ischemic cerebrovascular disease) who were enrolled in the Veterans With Premature Atherosclerosis (VITAL) registry. …”
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    Evaluation of Aspirin and Statin Therapy Use and Adherence in Patients With Premature Atherosclerotic Cardiovascular Disease
  7. 161087
    “…DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort included participants enrolled in the Whitehall II study and its MRI substudy based in the UK. …”
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    Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
  8. 161088
    “…Alemtuzumab-treated patients who enrolled in the extensions could receive additional courses ≥ 12 months apart. …”
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    Efficacy and Safety of Alemtuzumab Through 9 Years of Follow-up in Patients with Highly Active Disease: Post Hoc Analysis of CARE-MS I and II Patients in the TOPAZ Extension Study
  9. 161089
    Publicado 2020
    “…RESULTS: ①Total 288 patients were enrolled in the study, including 182 men and 106 women, with a median age of 18 (6–62) years. …”
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    恶性血液病单倍型造血干细胞移植预处理中兔抗人胸腺细胞球蛋白剂量优化探讨
  10. 161090
    “…DESIGN, SETTING, AND PARTICIPANTS: This multicenter prospective diagnostic study, conducted by the National Collegiate Athletics Association–Department of Defense Concussion Assessment, Research, and Education Consortium, included 127 male and female athletes who had sustained an SRC while enrolled at 6 Concussion Assessment, Research, and Education Consortium Advanced Research Core sites as well as 2 partial–Advanced Research Core military service academies. …”
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    Plasma Biomarker Concentrations Associated With Return to Sport Following Sport-Related Concussion in Collegiate Athletes—A Concussion Assessment, Research, and Education (CARE) Consortium Study
  11. 161091
    “…METHODS: Adults aged ≥18 years with T2D and a baseline glycated hemoglobin (HbA1c) of ≥8% to ≤12% were enrolled from 2 primary care centers from February 2019 to October 2019. …”
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    Glycemic Outcomes in Adults With Type 2 Diabetes Participating in a Continuous Glucose Monitor–Driven Virtual Diabetes Clinic: Prospective Trial
  12. 161092
    “…DESIGN, SETTING, AND PARTICIPANTS: Between October 24, 2013, and September 27, 2016, the EVRA randomized clinical trial enrolled 450 participants (450 legs) with venous leg ulceration of less than 6 months’ duration and superficial venous reflux. …”
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    Long-term Clinical and Cost-effectiveness of Early Endovenous Ablation in Venous Ulceration: A Randomized Clinical Trial
  13. 161093
    Publicado 2020
    “…Among them, 57 had been treated with CsA + rhTPO, TPO was administered at 15 000 U QD for 7 days, once a month for 3 months, and the other 26 patients with compatible baseline characters were treated with CsA alone. All the enrolled patients had been treated with CsA for at least 6 months and were followed up for at least 1 year. …”
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    重组人血小板生成素对非重型再生障碍性贫血免疫抑制治疗疗效的影响
  14. 161094
    “…Analysis of covariance models, controlling for baseline hemoglobin A(1c), were used to evaluate 3-month hemoglobin A(1c) differences in intent-to-treat (ITT) and per protocol (PP) analyses. RESULTS: The enrolled sample (N=95) had a mean age of 41 (SD 11) years, was 73% female, 88% White, diagnosed for a mean of 20 (SD 11) years, and had a mean hemoglobin A(1c) level of 8.4% (SD 1.2%); 11% of the participants did not complete follow up. …”
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    One Drop App With an Activity Tracker for Adults With Type 1 Diabetes: Randomized Controlled Trial
  15. 161095
    “…DESIGN, SETTING, AND PARTICIPANTS: This population-based cohort study included 173 580 patients in Ontario, Canada, with nonmetastatic cancer of the prostate, bladder, colon, rectum or anus, cervix, uterus, or testis. Patients were enrolled from January 1, 2002, to January 31, 2017. …”
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    Assessment of Secondary Sarcomas Among Patients With Cancer of the Abdomen or Pelvis Who Received Combinations of Surgery, Radiation, and Chemotherapy vs Surgery Alone
  16. 161096
    “…METHODS: All patients of the year 2018 diagnosed with a primary ACL instability and treated by one single surgeon were enrolled and prospectively assessed. Follow-up at 12 weeks postoperatively was performed using a functional “return-to-sports” analysis including isokinetic and isometric strength measurement (quad/ham ratio, BTE-primus), postural stability tests (MTF balance score), tapping test (force plate, Bertec) and a 3d-motion analysis (myomotion, Noraxon) during bilateral drop jumps and single leg hop tests (uni- and bilateral drop-jump, bilateral Counter Movement-Jump, Single-Leg Hop for Distance). …”
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    Return to sports following ACL reconstruction: prospective analysis of functional stability 3 months postoperatively in 280 patients
  17. 161097
    “…Tumor specimens from 36 chemonaive breast cancer patients with known ER and PgR status (18 ER(+)/PgR(−) and 18 ER(−)/PgR(+) cases) were enrolled to the study. The expression of 829 miRNAs was evaluated with nCounter Human v3 miRNA expression Assay (NanoString). miRNAs differentiating between ER/PgR/HER2 phenotypes were selected based on fold change (FC) calculated for the mean normalized counts of each probe in compared groups. …”
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    microRNA Expression Profile in Single Hormone Receptor-Positive Breast Cancers Is Mainly Dependent on HER2 Status—A Pilot Study
  18. 161098
    “…RESULTS: Interested individuals (N=605) enrolled on a website and were randomized into 3 groups (S, n=201; S+pSMS, n=202; S+VCS, n=201). …”
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    The Influence of Three Modes of Human Support on Attrition and Adherence to a Web- and Mobile App–Based Mental Health Promotion Intervention in a Nonclinical Cohort: Randomized Comparative Study
  19. 161099
    “…METHODS AND FINDINGS: Samples were collected between 2005 and 2015 from 618 children and adolescents enrolled in the Chronic Kidney Disease in Children study, an observational cohort study of pediatric CKD patients from the US and Canada. …”
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    Serially assessed bisphenol A and phthalate exposure and association with kidney function in children with chronic kidney disease in the US and Canada: A longitudinal cohort study
  20. 161100
    “…We descriptively analysed the demographics, service preferences, and baseline symptoms of patients. Among patients enrolled in a digital treatment course, we evaluated scales of depression (Patient Health Questionnaire-9 [PHQ-9]) and anxiety (Generalized Anxiety Disorder 7-Item Scale [GAD-7]), as primary measures of treatment outcome, from the screening assessment to post-treatment and a 3 month follow-up. …”
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    User characteristics and outcomes from a national digital mental health service: an observational study of registrants of the Australian MindSpot Clinic
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