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  1. 161661
    “…METHODS: Peripheral blood from 15 COVID-19 patients in early stage of infection (day 1-14, confirmed by RT-PCR), categorized according comorbidities in: G1 (not oncologic; n = 6), G2 (oncologic; n = 3), G3 (hematologic neoplasms; n = 3) and G4 (without comorbidities; n = 3), and 10 healthy samples enrolled the study. Clinical and laboratorial data were collected from electronic medical records. …”
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    ANTIVIRAL RESPONSE OF NATURAL KILLER CELLS IN EARLY STAGE OF COVID-19 PATIENTS
  2. 161662
    por Angyal, Adrienn, Longet, Stephanie, Moore, Shona C, Payne, Rebecca P, Harding, Adam, Tipton, Tom, Rongkard, Patpong, Ali, Mohammad, Hering, Luisa M, Meardon, Naomi, Austin, James, Brown, Rebecca, Skelly, Donal, Gillson, Natalie, Dobson, Sue L, Cross, Andrew, Sandhar, Gurjinder, Kilby, Jonathan A, Tyerman, Jessica K, Nicols, Alexander R, Spegarova, Jarmila S, Mehta, Hema, Hornsby, Hailey, Whitham, Rachel, Conlon, Christopher P, Jeffery, Katie, Goulder, Philip, Frater, John, Dold, Christina, Pace, Matthew, Ogbe, Ane, Brown, Helen, Ansari, M Azim, Adland, Emily, Brown, Anthony, Chand, Meera, Shields, Adrian, Matthews, Philippa C, Hopkins, Susan, Hall, Victoria, James, William, Rowland-Jones, Sarah L, Klenerman, Paul, Dunachie, Susanna, Richter, Alex, Duncan, Christopher J A, Barnes, Eleanor, Carroll, Miles, Turtle, Lance, de Silva, Thushan I
    Publicado 2022
    “…METHODS: We sampled health-care workers enrolled in the PITCH study across four hospital sites in the UK (Oxford, Liverpool, Newcastle, and Sheffield). …”
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    T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study
  3. 161663
    “…DESIGN, SETTING, AND PARTICIPANTS: This cohort study used data from patients enrolled in the Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI) project from December 2014 to December 2017. …”
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    Questionnaires vs Interviews for the Assessment of Global Functional Outcomes After Traumatic Brain Injury
  4. 161664
    “…DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study included 276 US physicians enrolled in the Intern Health Study since their first year of residency training. …”
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    Experiences of Work-Family Conflict and Mental Health Symptoms by Gender Among Physician Parents During the COVID-19 Pandemic
  5. 161665
    “…MATERIALS AND METHODS: Twenty patients were enrolled in this study. The study design included eight different sites (the cervical, nasopharyngeal, and oral cavities, rectum, prostate, bladder, lung, and esophagus). …”
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    Evaluation of Daily CT for EPID-Based Transit In Vivo Dosimetry
  6. 161666
    “…DESIGN, SETTING, AND PARTICIPANTS: Secondary analysis of data from the EMERGE and ENGAGE trials, which were 2 double-blind, placebo-controlled, parallel-group, phase 3 randomized clinical trials that compared low-dose and high-dose aducanumab treatment with placebo among participants at 348 sites across 20 countries. Enrollment occurred from August 2015 to July 2018, and the trials were terminated early (March 21, 2019) based on a futility analysis. …”
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    Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease
  7. 161667
    “…RESULTS: Of the 309 HCWs enrolled in the study, 205 received ChAdOx1 and 104 received BNT162b2. …”
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    Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
  8. 161668
    “…RESULTS: Overall, 16 studies focusing on 379 animals were enrolled into the study. The risk of bias score of included studies ranged from 4 to 7 with an average score of 5.25. …”
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    Antiosteoporosis Effect and Possible Mechanisms of the Ingredients of Fructus Psoraleae in Animal Models of Osteoporosis: A Preclinical Systematic Review and Meta-Analysis
  9. 161669
    “…Eligible patients had an AB prescription ±5 days of uUGG diagnosis (index date) and continuous health-plan enrollment with ≥ 6 months’ baseline/≥ 12 months’ follow-up data. …”
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    1358. A Real-World Study of the Burden of Illness and Treatment Patterns Among Patients with Uncomplicated Urogenital Gonorrhea in the United States
  10. 161670
    “…Patients had an oral AB prescription ± 5 days of the index date, and continuous health plan enrollment ≥ 6 months pre/1 year post-index date; those with complicated UTI were excluded. …”
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    1414. Real-World Study of Healthcare Resource Use and Costs Associated with Inappropriate and Suboptimal Antibiotic Use Among Females with Uncomplicated Urinary Tract Infection in the United States
  11. 161671
    “…Patients meeting the following criteria were included for analysis: (1) ≥18 years of age on the index date, (2) ≥6 months of continuous enrollment (CE) with medical and pharmacy benefits prior to the index date, (3) ≥12 months of CE following the index date or evidence of death, and (4) no evidence of a prior cUTI during the 6-month baseline period. …”
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    1439. Epidemiology and 12- Month Antibiotic Use in the Outpatient Setting among Adult Patients with Complicated Urinary Tract Infections: A Retrospective Database Analysis
  12. 161672
    “…BRAAVE 2020 study design (phase 3, randomized, open-label, multicenter [USA], active-controlled study) and virologic suppression at weeks 24 and 48 [Image: see text] *Allowed 3rd agents: any FDA-approved protease inhibitor, nonnucleoside reverse transcriptase inhibitor (except etravirine), integrase strand transfer inhibitor (except bictegravir), or maraviroc. METHODS: Enrollment criteria permitted NNRTI resistance (-R), PI-R, and certain NRTI-R (M184V/I allowed; K65R/E/N, ≥3 thymidine analog mutations [TAMs], or T69-insertions excluded) and excluded known primary INSTI-R. …”
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    629. High Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in African American Adults with HIV Including Those with Preexisting Resistance, Viral Blips, and Suboptimal Adherence
  13. 161673
    “…Methods: A total of 230 high-risk breast cancer patients from Fudan University Shanghai Cancer Center who had undergone peripheral blood germline 72 genes next-generation sequencing (NGS) from June 2018 to June 2020 were enrolled for retrospective analysis. The 72 genes include common hereditary breast cancer genes, such as homologous recombination repair (HRR) genes and other DNA damage repair genes. …”
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    Characteristics of Germline Non-BRCA Mutation Status of High-Risk Breast Cancer Patients in China and Correlation with High-Risk Factors and Multigene Testing Suggestions
  14. 161674
    “…We conducted a computer simulation study including the pelvis and THA prosthesis to answer the three study questions. We enrolled 10 patients who underwent robot-assisted THA for avascular necrosis of the femoral head (mean age 49 ± 19 years; five were women) from October 2019 to December 2019. …”
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    A Modeling Study of a Patient-specific Safe Zone for THA: Calculation, Validation, and Key Factors Based on Standing and Sitting Sagittal Pelvic Tilt
  15. 161675
    “…METHODS: We investigated a large-scale electronics manufacturer in the Pearl River Delta Region. We ultimately collected 699 qualified workers (248 with isopropanol exposure, 182 with lead exposure, 157 with noise exposure, and 112 controls). …”
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    Telomere length in peripheral leukocytes is a sensitive marker for assessing genetic damage among workers exposed to isopropanol, lead and noise: the case of an electronics manufacturer
  16. 161676
    “…Results: Two hundred and twenty-five children were enrolled in the study, 137 in the pre-implementation period and 88 in the post-implementation period. …”
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    The LiberAction Project: Implementation of a Pediatric Liberation Bundle to Screen Delirium, Reduce Benzodiazepine Sedation, and Provide Early Mobilization in a Human Resource-Limited Pediatric Intensive Care Unit
  17. 161677
    “…METHODS: Patients undergoing elective foot/ankle surgery at a single center were prospectively enrolled. Demographics, diagnoses, and preoperative Foot and Ankle Outcomes Scores (FAOS) were collected. …”
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    Influence of Depression and Anxiety on Satisfaction and Expectation Fulfillment in Foot and Ankle Surgery
  18. 161678
    “…Sparse events sensitivity analysis was tested by fitting models with Firth log-likelihood approach; penalizing estimates for first-order bias correction and stability of regression coefficients. …”
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    Posterior Ankle and Hindfoot Arthroscopy: Complications and Posterior Ankle Impingement Pathologies
  19. 161679
    “…Our aim was to investigate the frequency of bleeding in hospitalized adult pts with cancer andCOVID-19, enrolled between March 16, 2020 and Feb 8, 2021. The incidence of bleeding complications was captured as defined by CCC19 and included both major and non major bleeding . …”
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    Bleeding Complications in Patients with Cancer and COVID 19- Analysis from the COVID 19and Cancer Consortium (CCC19) Registry
  20. 161680
    “…Among 1454 MGUS patients followed at our center, 91 were found SARS-CoV-2 positive, enrolled in this observational, retrospective study and compared with 182 age and sex-matched normal controls. …”
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    COVID-19 in Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS): An Observational Retrospective Study
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