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161741por Auchus, Richard J, Belaya, Zhanna, Bex, Marie, Feelders, Richard A, Heaney, Anthony P, Paul, Michaela, Pedroncelli, Alberto M, Snyder, Peter J, Turcu, Adina F, Witek, Przemysław, Gadelha, Mônica“…METHODS: 73 adults with CD and mUFC >1.3× the upper limit of normal (ULN) were enrolled. LINC 4 comprised a 12W, randomized, double-blind, placebo-controlled period followed by 36W of open-label osilodrostat. …”
Publicado 2022
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161742por Chen, Huijun, Zhang, Xiaoli, Cai, Sufen, Li, Jian, Tang, Sha, Hocher, Carl-Friedrich, Rösing, Benjamin, Hu, Liang, Lin, Ge, Gong, Fei, Krämer, Bernhard K, Hocher, Berthold“…PARTICIPANTS/MATERIALS, SETTING, METHODS: Two thousand four hundred and eighteen women with normal blood pressure undergoing fresh embryo transfer after IVF/ICSI at the Reproductive and Genetic Hospital of CITIC-Xiangya were enrolled in this study. MAIN RESULTS AND THE ROLE OF CHANCE: Blood pressure was measured at the first visit when women consulted the IVF center due to infertility. …”
Publicado 2022
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161743por Amuge, Pauline, Lugemwa, Abbas, Wynne, Ben, Mujuru, Hilda A, Violari, Avy, Kityo, Cissy M, Archary, Moherndran, Variava, Ebrahim, White, Ellen, Turner, Rebecca M, Shakeshaft, Clare, Ali, Shabinah, Nathoo, Kusum J, Atwine, Lorna, Liberty, Afaaf, Bbuye, Dickson, Kaudha, Elizabeth, Mngqibisa, Rosie, Mosala, Modehei, Mumbiro, Vivian, Nanduudu, Annet, Ankunda, Rogers, Maseko, Lindiwe, Kekitiinwa, Adeodata R, Giaquinto, Carlo, Rojo, Pablo, Gibb, Diana M, Turkova, Anna, Ford, Deborah“…Children weighing less than 14 kg starting first-line or second-line ART were enrolled in seven HIV treatment centres in South Africa, Uganda, and Zimbabwe. …”
Publicado 2022
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161744por Zhou, Minghan, Cheng, Jinlin, Zhao, Handan, Yang, Min, Yu, Wenjuan, Qin, Jiaying, Lang, Guanjing, Tao, Ran, Cao, Qing, Huang, Ying, Zhu, Biao, Xu, Lijun“…Methods: Fifty-three HIV-infected and ninety-three HIV-uninfected DLBCL patients were enrolled in the retrospective study by propensity score matching for sex, age, body mass index and international prognostic index (IPI) at a ratio of 1:2. …”
Publicado 2022
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161745por Yap, Timothy A., Bardia, Aditya, Dvorkin, Michael, Galsky, Matthew D., Beck, J. Thaddeus, Wise, David R., Karyakin, Oleg, Rubovszky, Gábor, Kislov, Nikolay, Rohrberg, Kristoffer, Joy, Anil Abraham, Telli, Melinda L., Schram, Alison M., Conte, Umberto, Chappey, Colombe, Stewart, Ross, Stypinski, Daria, Michelon, Elisabete, Cesari, Rossano, Konstantinopoulos, Panagiotis A.“…DESIGN, SETTING, AND PARTICIPANTS: In this phase 1b and 2 basket nonrandomized controlled trial, patients with advanced solid tumors were enrolled in the following cohorts: non–small cell lung cancer (NSCLC); DNA damage response (DDR)–positive NSCLC; triple-negative breast cancer (TNBC); hormone receptor–positive, human epidermal growth factor receptor 2 (ERBB2)–negative, DDR-positive breast cancer; recurrent, platinum-sensitive ovarian cancer (OC); recurrent, platinum-sensitive, BRCA1/2-altered OC; urothelial cancer; metastatic castration-resistant prostate cancer (mCRPC); DDR-positive mCRPC; and BRCA1/2- or ATM-altered solid tumors. …”
Publicado 2022
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161746por Sui, Youxin, Kan, Chaojie, Zhu, Shizhe, Zhang, Tianjiao, Wang, Jin, Xu, Sheng, Zhuang, Ren, Shen, Ying, Wang, Tong, Guo, Chuan“…METHODS: Forty-nine subacute (2 weeks−6 months) stroke patients with subcortical lesions were enrolled and were classified into three groups based on FMA-UE scores: mild impairment (n = 17), moderate impairment (n = 13), and severe impairment (n = 19). …”
Publicado 2022
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161747por Chen, Yanhong, Fu, Yu, Wang, Shixin, Chen, Pengsheng, Pei, Yunfeng, Zhang, Jiao, Zhang, Rui, Niu, Guoping, Gu, Feng, Li, Xiaoli“…METHODS: In this retrospective cohort study, 579 T2DM patients aged ≥ 65 years were consecutively enrolled in this work, and 177 of whom had major adverse cardiovascular and cerebrovascular events (MACCE: cardiovascular or cerebrovascular death, acute coronary syndrome, coronary stent implantation, and stroke) during the follow up. …”
Publicado 2022
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161748por Wumener, Xieraili, Zhang, Yarong, Wang, Zhenguo, Zhang, Maoqun, Zang, Zihan, Huang, Bin, Liu, Ming, Huang, Shengyun, Huang, Yong, Wang, Peng, Liang, Ying, Sun, Tao“…METHODS: One hundred and eight patients with pulmonary nodules were enrolled to perform (18)F-FDG PET/CT dynamic + static imaging with informed consent. …”
Publicado 2022
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161749por Urso, Luca, Evangelista, Laura, Alongi, Pierpaolo, Quartuccio, Natale, Cittanti, Corrado, Rambaldi, Ilaria, Ortolan, Naima, Borgia, Francesca, Nieri, Alberto, Uccelli, Licia, Schirone, Alessio, Panareo, Stefano, Arnone, Gaspare, Bartolomei, Mirco“…For each [(18)F]FDG PET/CT scan, semiquantitative parameters (SUVmax, SUVmean, MTV and TLG) related to the primary tumor (B), to the reference lesion for both axillary (N) and distant lymph node (DN), and to the whole-body burden of disease (WB) were evaluated. Patients enrolled were 133: 34 from centre A and 99 from centre B. …”
Publicado 2022
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161750por Shiri, Isaac, Vafaei Sadr, Alireza, Akhavan, Azadeh, Salimi, Yazdan, Sanaat, Amirhossein, Amini, Mehdi, Razeghi, Behrooz, Saberi, Abdollah, Arabi, Hossein, Ferdowsi, Sohrab, Voloshynovskiy, Slava, Gündüz, Deniz, Rahmim, Arman, Zaidi, Habib“…METHODS: Non-attenuation/scatter corrected and CT-based attenuation/scatter corrected (CT-ASC) (18)F-FDG PET images of 300 patients were enrolled in this study. The dataset consisted of 6 different centers, each with 50 patients, with scanner, image acquisition, and reconstruction protocols varying across the centers. …”
Publicado 2022
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161751por Richard, Stephanie A, Scher, Ann, Rusiecki, Jennifer, Byrne, Celia, Berjohn, Catherine M, Fries, Anthony C, Lalani, Tahaniyat, Smith, Alfred G, Mody, Rupal, Ganesan, Anuradha, Huprikar, Nikhil, Colombo, Rhonda E, Colombo, Christopher, Lindholm, David A, Mende, Katrin, Jones, Milissa, Larson, Derek, Ewers, Evan C, Bazan, Samantha, Lanteri, Charlotte, Saunders, David, Maves, Ryan C, Livezey, Jeffrey, Edwards, Margaret Sanchez, Rozman, Julia S, Tribble, David R, Agan, Brian, Pollett, Simon, Simons, Mark P, Burgess, Timothy“…Subjects completed surveys at enrollment and at 1, 3, 6, 9, and 12 months. RESULTS: 5,910 subjects completed survey fitness questions, 3,244 (55%) of whom tested SARS-CoV-2 positive at least once during the period of observation. …”
Publicado 2022
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161752por Gilbert, Madison, Joseph, Atarere, Turcinovic, Jacquelyn, Seitz, Scott, Sher-Jan, Cole, White, Laura F, Zhou, Zhenwei, Hossain, Mohammad, Zebelean, Devin, Overbeck, Victoria, Doucette-Stamm, Lynn, Platt, Judy T, Nichols, Hannah E, Hamer, Davidson H, Klapperich, Catherine M, Jacobson, Karen R, Connor, John, Bouton, Tara C“…METHODS: CoViD Post-vax is longitudinal cohort study collecting baseline clinical questionnaires, and daily anterior nasal swabs and symptom screens on enrolled Boston University SARS-CoV-2 PCR-positive cases detected through a serial screening testing program or symptomatic testing. …”
Publicado 2022
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161753por Li, Yijia, Harrison, Linda J, Chew, Kara W, Eron, Joseph J, Daar, Eric S, Wohl, David A, Wu, Ryan, Moser, Carlee, Ritz, Justin, Giganti, Mark, Javan, Arzhang Cyrus, Coombs, Robert, Hughes, Michael D, Currier, Judith S, Smith, Davey M, Li, Jonathan Z“…METHODS: ACTIV-2/A5401 is a platform trial for COVID-19 treatments in non-hospitalized symptomatic adults enrolled within 10 days of symptom onset. We included participants randomized to placebo from August 2020 to July 2021. …”
Publicado 2022
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161754por Ogbuagu, Onyema, Segal-Maurer, Sorana, Ratanasuwan, Winai, Trottier, Benoit, Brunetta, Jason, Shirasaka, Takuma, Koenig, Ellen L, Wang, Hui, Margot, Nicolas A, Dvory-Sobol, Hadas, Rhee, Martin S, Baeten, Jared, Molina, Jean-Michel“…RESULTS: Of 72 participants enrolled, 25% were female, 38% Black, median age 52 years, 64% had CD4 < 200 cells/µL, 46% had HIV-1 resistant to all 4 major classes (NRTI, NNRTI, PI, INSTI), and 53% had OBR with 1 or no fully active agents. …”
Publicado 2022
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161755por Sasidharan, Anjana, Shore, Kayla, Lee, Brian R, Harrison, Christopher J, Schuster, Jennifer E, Moffatt, Mary E, Weltmer, Kirsten, Wikswo, Mary, Emery, Brian D, Oberste, Steven, Selvarangan, Rangaraj“…METHODS: From December 2011 – November 2018, we screened stool samples from children less than 18 years of age prospectively enrolled in Children’s Mercy-Kansas City’s (CM-KC) site for the CDC’s New Vaccine Surveillance Network; 3005 samples from subjects presenting with AGE and 1097 from HC. …”
Publicado 2022
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161756por DiazGranados, Carlos A, Bonaparte, Matthew, Wang, Hao, Zhu, Ming, Lustig, Yaniv, Schwartz, Eli, Forrat, Remi, Dayan, Gustavo H, Hodge, Shekema, Ataman-Önal, Yasemin, Savarino, Stephen J“…METHODS: We included participants in the immunogenicity subsets of the phase 3 CYD14 (NCT01373281) and CYD15 (NCT01374516) CYD-TDV efficacy trials, which enrolled children aged 2–16 years in 2011–12 in five countries in the Asia-Pacific region (CYD14) and five Latin American countries (CYD15). …”
Publicado 2021
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161757por Clark, Tristan W, Beard, Kate R, Brendish, Nathan J, Malachira, Ahalya K, Mills, Samuel, Chan, Cathleen, Poole, Stephen, Ewings, Sean, Cortes, Nick, Nyimbili, Esther, Presland, Laura“…FINDINGS: Between Dec 12, 2017, and May 3, 2019, over two influenza seasons, 613 patients were enrolled, of whom 307 were assigned to the mPOCT group and 306 to the control group, and all were analysed. …”
Publicado 2021
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161758por Davis, Derik L., Almardawi, Ranyah, Awan, Omer A., Lo, Lawrence Y., Ahmed, Sagheer R., Jubouri, Shams, Gullapalli, Rao P.“…Forty adults, 60–85 years, were enrolled at baseline; one follow-up visit at ≥6 months. …”
Publicado 2022
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161759por Ullah, Asad, Khan, Jaffar, Waheed, Abdul, Karki, Nabin Raj, Goodbee, Mya, Yasinzai, Abdul Qahar Khan, Tareen, Bisma, Wali, Agha, Khan, Khaleel Ahmad, Zarak, Muhammad Samsoor, Khan, Israr, Garcia, Andrea Agualimpia, Khan, Adil, Khan, Marjan, Jogezai, Sana, Ahmad, Junaid, Zarate, Luis Velasquez, Patel, Nikhil, Karim, Nagla Abdel, Heneidi, Saleh“…This study sought to evaluate the demographic and clinical factors affecting outcomes in adults and pediatric populations with MEC that could be used to risk stratification for treatment selection and clinical trial enrollment. Methods: Data on 4507 MEC patients were extracted from the Surveillance Epidemiology and End Result (SEER) database (2000–2018). …”
Publicado 2022
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161760por Fernandez Turienzo, Cristina, Hull, Louise H., Coxon, Kirstie, Bollard, Mary, Cross, Pauline, Seed, Paul T., Shennan, Andrew H., Sandall, Jane“…RESULTS: Between May 9, 2017, and Sep 30, 2018, 553 women were assessed for eligibility and 334 were enrolled with less than 6% of loss to follow up (169 were assigned to the POPPIE group; 165 were to the standard group). …”
Publicado 2023
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