Modulation of splicing catalysis for therapeutic targeting of leukemias with spliceosomal mutations

por Lee, Stanley Chun-Wei, Dvinge, Heidi, Kim, Eunhee, Cho, Hana, Micol, Jean-Baptiste, Chung, Young Rock, Durham, Benjamin H., Yoshimi, Akihide, Kim, Young Joon, Thomas, Michael, Lobry, Camille, Chen, Chun-Wei, Pastore, Alessandro, Taylor, Justin, Wang, Xujun, Krivtsov, Andrei, Armstrong, Scott A., Palacino, James, Buonamici, Silvia, Smith, Peter G., Bradley, Robert K., Abdel-Wahab, Omar
Publicado 2016

DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling

por Martin, Pierre-Marie, Stanley, Robert E., Ross, Adam P., Freitas, Andiara E., Moyer, Caitlin E., Brumback, Audrey C., Iafrati, Jillian, Stapornwongkul, Kristina S., Dominguez, Sky, Kivimäe, Saul, Mulligan, Kimberly A., Pirooznia, Mehdi, McCombie, W. Richard, Potash, James B., Zandi, Peter P., Purcell, Shaun M., Sanders, Stephan J., Zuo, Yi, Sohal, Vikaas S., Cheyette, Benjamin N.R.
Publicado 2016

Science, not speculation, is essential to determine how SARS-CoV-2 reached humans

por Calisher, Charles H, Carroll, Dennis, Colwell, Rita, Corley, Ronald B, Daszak, Peter, Drosten, Christian, Enjuanes, Luis, Farrar, Jeremy, Field, Hume, Golding, Josie, Gorbalenya, Alexander E, Haagmans, Bart, Hughes, James M, Keusch, Gerald T, Lam, Sai Kit, Lubroth, Juan, Mackenzie, John S, Madoff, Larry, Mazet, Jonna Keener, Perlman, Stanley M, Poon, Leo, Saif, Linda, Subbarao, Kanta, Turner, Michael
Publicado 2021

Phase II Study of Palbociclib (PD-0332991) in CCND1, 2, or 3 Amplification: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1B

por Clark, Amy S., Hong, Fangxin, Finn, Richard S., DeMichele, Angela M., Mitchell, Edith P., Zwiebel, James, Arnaldez, Fernanda I., Gray, Robert J., Wang, Victoria, McShane, Lisa M., Rubinstein, Larry V., Patton, David, Williams, P. Mickey, Hamilton, Stanley R., Copur, Mehmet S., Kasbari, Samer S., Thind, Ravneet, Conley, Barbara A., Arteaga, Carlos L., O'Dwyer, Peter J., Harris, Lyndsay N., Chen, Alice P., Flaherty, Keith T.
Publicado 2023

Implementation, mechanisms of impact and key contextual factors involved in outcomes of the Modification of Diet, Exercise and Lifestyle (MODEL) randomised controlled trial in Aust...

por Anokye, Reindolf, Radavelli-Bagatini, Simone, Bondonno, Catherine P, Sim, Marc, Blekkenhorst, Lauren C, Connolly, Emma, Bondonno, Nicola P, Schousboe, John T, Woodman, Richard, Zhu, Kun, Szulc, Pawel, Jackson, Ben, Dimmock, James, Schlaich, Markus P, Cox, Kay L, Kiel, Douglas P, Lim, Wai H, Devine, Amanda, Thompson, Peter L, Gianoudis, Jenny, De Ross, Belinda, Daly, Robin M, Hodgson, Jonathan M, Lewis, Joshua R, Stanley, Mandy
Publicado 2020

Mycoplasma genitalium and Other Reproductive Tract Infections in Pregnant Women, Papua New Guinea, 2015–2017

por Scoullar, Michelle J.L., Boeuf, Philippe, Peach, Elizabeth, Fidelis, Ruth, Tokmun, Kerryanne, Melepia, Pele, Elijah, Arthur, Bradshaw, Catriona S., Fehler, Glenda, Siba, Peter M., Erskine, Simon, Mokany, Elisa, Kennedy, Elissa, Umbers, Alexandra J., Luchters, Stanley, Robinson, Leanne J., Wong, Nicholas C., Vallely, Andrew J., Badman, Steven G., Vallely, Lisa M., Fowkes, Freya J.I., Morgan, Christopher, Pomat, William, Crabb, Brendan S., Beeson, James G.
Publicado 2021

Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement

por Bartlett, Stephen T., Markmann, James F., Johnson, Paul, Korsgren, Olle, Hering, Bernhard J., Scharp, David, Kay, Thomas W. H., Bromberg, Jonathan, Odorico, Jon S., Weir, Gordon C., Bridges, Nancy, Kandaswamy, Raja, Stock, Peter, Friend, Peter, Gotoh, Mitsukazu, Cooper, David K. C., Park, Chung-Gyu, O'Connell, Phillip, Stabler, Cherie, Matsumoto, Shinichi, Ludwig, Barbara, Choudhary, Pratik, Kovatchev, Boris, Rickels, Michael R., Sykes, Megan, Wood, Kathryn, Kraemer, Kristy, Hwa, Albert, Stanley, Edward, Ricordi, Camillo, Zimmerman, Mark, Greenstein, Julia, Montanya, Eduard, Otonkoski, Timo
Publicado 2016

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

por Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Publicado 2016

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

por Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.
Publicado 2016

Modification of diet, exercise and lifestyle (MODEL) study: a randomised controlled trial protocol

por Radavelli-Bagatini, Simone, Bondonno, Catherine P, Sim, Marc, Blekkenhorst, Lauren C, Anokye, Reindolf, Connolly, Emma, Bondonno, Nicola P, Schousboe, John T, Woodman, Richard J, Zhu, Kun, Szulc, Pawel, Jackson, Ben, Dimmock, James, Schlaich, Markus P, Cox, Kay L, Kiel, Douglas P, Lim, Wai H, Stanley, Mandy, Devine, Amanda, Thompson, Peter L, Gianoudis, Jenny, De Ross, Belinda, Daly, Robin M, Lewis, Joshua R, Hodgson, Jonathan M
Publicado 2020

Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)

por Flaherty, Keith T., Gray, Robert J., Chen, Alice P., Li, Shuli, McShane, Lisa M., Patton, David, Hamilton, Stanley R., Williams, P. Mickey, Iafrate, A. John, Sklar, Jeffrey, Mitchell, Edith P., Harris, Lyndsay N., Takebe, Naoko, Sims, David J., Coffey, Brent, Fu, Tony, Routbort, Mark, Zwiebel, James A., Rubinstein, Larry V., Little, Richard F., Arteaga, Carlos L., Comis, Robert, Abrams, Jeffrey S., O’Dwyer, Peter J., Conley, Barbara A.
Publicado 2020

Limiting Mrs2-dependent mitochondrial Mg(2+) uptake induces metabolic programming in prolonged dietary stress

por Madaris, Travis R., Venkatesan, Manigandan, Maity, Soumya, Stein, Miriam C., Vishnu, Neelanjan, Venkateswaran, Mridula K., Davis, James G., Ramachandran, Karthik, Uthayabalan, Sukanthathulse, Allen, Cristel, Osidele, Ayodeji, Stanley, Kristen, Bigham, Nicholas P., Bakewell, Terry M., Narkunan, Melanie, Le, Amy, Karanam, Varsha, Li, Kang, Mhapankar, Aum, Norton, Luke, Ross, Jean, Aslam, M. Imran, Reeves, W. Brian, Singh, Brij B., Caplan, Jeffrey, Wilson, Justin J., Stathopulos, Peter B., Baur, Joseph A., Madesh, Muniswamy
Publicado 2023

Trametinib in Patients With NF1-, GNAQ-, or GNA11-Mutant Tumors: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols S1 and S2

por Wisinski, Kari B., Flamand, Yael, Wilson, Melissa A., Luke, Jason J., Tawbi, Hussein A., Hong, Fangxin, Mitchell, Edith P., Zwiebel, James A., Chen, Helen, Gray, Robert J., Li, Shuli, McShane, Lisa M., Rubinstein, Lawrence V., Patton, David, Williams, P. Mickey, Hamilton, Stanley R., Behrens, Robert J., Pennington, Kathryn P., Conley, Barbara A., Arteaga, Carlos L., Harris, Lyndsay N., O'Dwyer, Peter J., Chen, Alice P., Flaherty, Keith T.
Publicado 2023

Dapagliflozin vs. metolazone in heart failure resistant to loop diuretics

por Yeoh, Su Ern, Osmanska, Joanna, Petrie, Mark C, Brooksbank, Katriona J M, Clark, Andrew L, Docherty, Kieran F, Foley, Paul W X, Guha, Kaushik, Halliday, Crawford A, Jhund, Pardeep S, Kalra, Paul R, McKinley, Gemma, Lang, Ninian N, Lee, Matthew M Y, McConnachie, Alex, McDermott, James J, Platz, Elke, Sartipy, Peter, Seed, Alison, Stanley, Bethany, Weir, Robin A P, Welsh, Paul, McMurray, John J V, Campbell, Ross T
Publicado 2023

The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design

por Flaherty, Keith T, Gray, Robert, Chen, Alice, Li, Shuli, Patton, David, Hamilton, Stanley R, Williams, Paul M, Mitchell, Edith P, Iafrate, A John, Sklar, Jeffrey, Harris, Lyndsay N, McShane, Lisa M, Rubinstein, Larry V, Sims, David J, Routbort, Mark, Coffey, Brent, Fu, Tony, Zwiebel, James A, Little, Richard F, Marinucci, Donna, Catalano, Robert, Magnan, Rick, Kibbe, Warren, Weil, Carol, Tricoli, James V, Alexander, Brian, Kumar, Shaji, Schwartz, Gary K, Meric-Bernstam, Funda, Lih, Chih-Jian, McCaskill-Stevens, Worta, Caimi, Paolo, Takebe, Naoko, Datta, Vivekananda, Arteaga, Carlos L, Abrams, Jeffrey S, Comis, Robert, O’Dwyer, Peter J, Conley, Barbara A
Publicado 2020

Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a...

por Ebinger, Joseph E, Joung, Sandy, Liu, Yunxian, Wu, Min, Weber, Brittany, Claggett, Brian, Botting, Patrick G, Sun, Nancy, Driver, Matthew, Kao, Yu Hung, Khuu, Briana, Wynter, Timothy, Nguyen, Trevor-Trung, Alotaibi, Mona, Prostko, John C, Frias, Edwin C, Stewart, James L, Goodridge, Helen S, Chen, Peter, Jordan, Stanley C, Jain, Mohit, Sharma, Sonia, Fert-Bober, Justyna, Van Eyk, Jennifer E, Minissian, Margo B, Arditi, Moshe, Melmed, Gil Y, Braun, Jonathan G, McGovern, Dermot P B, Cheng, Susan, Sobhani, Kimia
Publicado 2022

Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer

por Kruse, Megan L., Patel, Mona, McManus, Jeffrey, Chung, Yoon-Mi, Li, Xiuxiu, Wei, Wei, Bazeley, Peter S., Nakamura, Fumihiko, Hardaway, Aimalie, Downs, Erinn, Chandarlapaty, Sarat, Thomas, Mathew, Moore, Halle C.F., Budd, George T., Tang, W.H. Wilson, Hazen, Stanley L., Bernstein, Aaron, Nik-Zainal, Serena, Abraham, Jame, Sharifi, Nima
Publicado 2021

Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual...

por Merritt, Kate, McGuire, Philip K., Egerton, Alice, Aleman, André, Block, Wolfgang, Bloemen, Oswald J. N., Borgan, Faith, Bustillo, Juan R., Capizzano, Aristides A., Coughlin, Jennifer Marie, De la Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q., Du, Fei, Falkai, Peter, Galinska-Skok, Beata, Gallinat, Jurgen, Gasparovic, Charles, Ginestet, Cedric E., Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng Choon, Howes, Oliver D., Jauhar, Sameer, Jeon, Peter, Kato, Tadafumi, Kaufmann, Charles A., Kegeles, Lawrence S., Keshavan, Matcheri, Kim, Sang-Young, Kunugi, Hiroshi, Lauriello, John, Liemburg, Edith Jantine, Mcilwain, Meghan E., Modinos, Gemma, Mouchlianitis, Elias D., Nakamura, Jun, Nenadic, Igor, Öngür, Dost, Ota, Miho, Palaniyappan, Lena, Pantelis, Christos, Plitman, Eric, Posporelis, Sotirios, Purdon, Scot E., Reichenbach, Jürgen R., Renshaw, Perry F., Russell, Bruce R., Sawa, Akira, Schaefer, Martin, Shungu, Dikoma C., Smesny, Stefan, Stanley, Jeffrey A., Stone, James M., Szulc, Agata, Taylor, Reggie, Thakkar, Katy, Théberge, Jean, Tibbo, Philip G., van Amelsvoort, Therese, Walecki, Jerzy, Williamson, Peter C., Wood, Stephen James, Xin, Lijing, Yamasue, Hidenori
Publicado 2021

Genome-Wide Analysis of Copy Number Variants in Attention Deficit Hyperactivity Disorder: The Role of Rare Variants and Duplications at 15q13.3

por Williams, Nigel M., Franke, Barbara, Mick, Eric, Anney, Richard J.L., Freitag, Christine M., Gill, Michael, Thapar, Anita, O'Donovan, Michael C., Owen, Michael J., Holmans, Peter, Kent, Lindsey, Middleton, Frank, Zhang-James, Yanli, Liu, Lu, Meyer, Jobst, Nguyen, Thuy Trang, Romanos, Jasmin, Romanos, Marcel, Seitz, Christiane, Renner, Tobias J., Walitza, Susanne, Warnke, Andreas, Palmason, Haukur, Buitelaar, Jan, Rommelse, Nanda, Vasquez, Alejandro Arias, Hawi, Ziarih, Langley, Kate, Sergeant, Joseph, Steinhausen, Hans-Christoph, Roeyers, Herbert, Biederman, Joseph, Zaharieva, Irina, Hakonarson, Hakon, Elia, Josephine, Lionel, Anath C., Crosbie, Jennifer, Marshall, Christian R., Schachar, Russell, Scherer, Stephen W., Todorov, Alexandre, Smalley, Susan L., Loo, Sandra, Nelson, Stanley, Shtir, Corina, Asherson, Philip, Reif, Andreas, Lesch, Klaus-Peter, Faraone, Stephen V.
Publicado 2012

Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine

por Benkeser, David, Fong, Youyi, Janes, Holly E., Kelly, Elizabeth J., Hirsch, Ian, Sproule, Stephanie, Stanley, Ann Marie, Maaske, Jill, Villafana, Tonya, Houchens, Christopher R., Martins, Karen, Jayashankar, Lakshmi, Castellino, Flora, Ayala, Victor, Petropoulos, Christos J., Leith, Andrew, Haugaard, Deanne, Webb, Bill, Lu, Yiwen, Yu, Chenchen, Borate, Bhavesh, van der Laan, Lars W. P., Hejazi, Nima S., Carpp, Lindsay N., Randhawa, April K., Andrasik, Michele P., Kublin, James G., Isaacs, Margaret Brewinski, Makhene, Mamodikoe, Tong, Tina, Robb, Merlin L., Corey, Lawrence, Neuzil, Kathleen M., Follmann, Dean, Hoffman, Corey, Falsey, Ann R., Sobieszczyk, Magdalena, Koup, Richard A., Donis, Ruben O., Gilbert, Peter B.
Publicado 2023