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Mostrando 321 - 340 Resultados de 4,819 Para Buscar 'Pirimidina~', tiempo de consulta: 5.15s Limitar resultados
  1. 321
    “…In the title compound, C(11)H(9)ClN(4)O(2), the dihedral angle between the aromatic rings is 79.67 (8)°. π–π stacking between centrosymmetrically related pairs of pyrimidine rings occurs along [100] [centroid–centroid separations = 3.4572 (8) and 3.5433 (7) Å].…”
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    6-Chloro-N-methyl-5-nitro-N-phenyl­pyrimidin-4-amine
  2. 322
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    4-Nitro­benzoic acid–N-(pyrimidin-2-yl)aniline (1/1)
  3. 323
    “…Their main difference is the torsion angles, ranging from 1.6 (5) to 5.9 (5)°, between the methyl group and the pyrimidine plane. A pair of inter­molecular N—H⋯N hydrogen bonds link mol­ecules A and C into a twisted dimer with a dihedral angle of 32.9 (1)° between the two pyrimidine rings, creating an R (2) (2)(8) motif. …”
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    6-Chloro-N (4),N (4)-dimethyl­pyrimidine-2,4-diamine
  4. 324
    “…In the title compound, C(13)H(10)BrN(3)O(3), the pyrimidine and benzene rings are twisted with an inter­planar angle of 58.4 (1)°. …”
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    Methyl 4-[N-(5-bromo­pyrimidin-2-yl)carbamo­yl]benzoate
  5. 325
    “…A new series of pyrazolo[3,4-d]pyrimidines has been synthesized. The new compounds were tested for their antitumor activity on 60 different cell lines, and some of the compounds were found to have potent antitumor activity. …”
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    Design, Synthesis, and Antitumor Evaluation of Novel Pyrazolo[3,4-d]pyrimidine Derivatives
  6. 326
    “…BACKGROUND: Imidazo[1,2-a]pyridines and pyrimidines are important organic fluorophores which have been investigated as biomarkers and photochemical sensors. …”
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    Fluorescent property of 3-hydroxymethyl imidazo[1,2-a]pyridine and pyrimidine derivatives
  7. 327
    “…The dihedral angle between the phenyl and pyrimidine ring is 16.49 (6)°. An intra­molecular N—H⋯N hydrogen bond stabilizes the mol­ec­ular conformation. …”
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    1-(2-Chloro­benzo­yl)-3-(pyrimidin-2-yl)thio­urea
  8. 328
    “…The fused pyrazole and pyrimidine rings in the title compound, C(13)H(10)ClN(3), are almost coplanar, their planes being inclined to one another by 0.8 (2)°. …”
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    7-Chloro-5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidine
  9. 329
    “…In the crystal of the title compound, C(6)H(9)N(3)·C(6)H(8)O(2), the 2-amino-4,6-di­methyl­pyrimidine and sorbic acid mol­ecules are linked through N—H⋯O and O—H⋯N hydrogen bonds, which generate a cyclic bimolecular heterosynthon with an R (2) (2)(8) graph-set motif. …”
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    2-Amino-4,6-di­methyl­pyrimidine–sorbic acid (1/1)
  10. 330
    “…Here we study the mechanism of the formation of a complex flower-shaped supramolecular structure of pyrimido[4,5-d]pyrimidine nucleosides by dynamic light scattering, scanning electron microscopy, differential scanning calorimetry, nuclear magnetic resonance and X-ray analysis. …”
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    Complex self-assembly of pyrimido[4,5-d]pyrimidine nucleoside supramolecular structures
  11. 331
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    2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S-Adenosyltransferase-2
  12. 332
    “…Under the auspices of the Pilot Scale Library Program of the NIH Roadmap Initiative, we produced and report herein a diverse library of 181 purine, pyrimidine, and 1,2,4-triazole-N-acetamide analogues which were prepared in a parallel high throughput solution-phase reaction format. …”
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    Solution-Phase Parallel Synthesis of Acyclic Nucleoside Libraries of Purine, Pyrimidine, and Triazole Acetamides
  13. 333
    “…Based on pharmacophore of the CRF1 receptor antagonists, a new series of thiazolo[4,5-d] pyrimidines were synthesized as Corticotropin-releasing factor (CRF) receptor modulators and the prepared compounds carry groups shown to produce optimum binding affinity to CRF receptors. …”
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    Synthesis of New Thiazolo[4,5-d]pyrimidines as Corticotropin Releasing Factor Modulators
  14. 334
    “…We present the first atomic-resolution pictures of the detrimental DNA cross-links of neighboring pyrimidine bases within the nucleosome, and provide the mechanistic framework for lesion recognition by UV-DDB in chromatin.…”
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    Structural basis of pyrimidine-pyrimidone (6–4) photoproduct recognition by UV-DDB in the nucleosome
  15. 335
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    Diversion of aspartate in ASS1-deficient tumors fosters de novo pyrimidine synthesis
  16. 336
    “…Herein we show that covalent modification of one or both of the pyrimidine bases by an osmium bipyridine complex leads to measureable differences in the blockade amplitudes of DNA molecules. …”
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    Osmium-Based Pyrimidine Contrast Tags for Enhanced Nanopore-Based DNA Base Discrimination
  17. 337
    “…Overall, we find that Hoogsteen-position pyrimidines support triple helix stability and function and that thermodynamic stability, based on EMSA results, is necessary but not sufficient for stabilization activity of the MALAT1 triple helix in cells. …”
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    Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix
  18. 338
    “…The integrated -omics data indicate purine and pyrimidine metabolism pathway activity differences between PLF and PSF mice. …”
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    Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans
  19. 339
    “…The human pathogenic parasite Trypanosoma brucei possess both de novo and salvage routes for the biosynthesis of pyrimidine nucleotides. Consequently, they do not require salvageable pyrimidines for growth. …”
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    Pyrimidine Salvage Enzymes Are Essential for De Novo Biosynthesis of Deoxypyrimidine Nucleotides in Trypanosoma brucei
  20. 340
    “…Given the unique properties of the OCF(3) group and the ubiquity of pyridine and pyrimidine in biologically active molecules and functional materials, trifluoromethoxylated pyridines and pyrimidines could serve as valuable building blocks for the discovery and development of new drugs, agrochemicals, and materials.…”
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    Access to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines
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