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Mostrando 501 - 520 Resultados de 4,819 Para Buscar 'Pirimidina~', tiempo de consulta: 4.69s Limitar resultados
  1. 501
    “…This quinoline carboxylic acid directly inhibited dihydroorotate dehydrogenase (DHODH), a host enzyme required for de novo pyrimidine biosynthesis, and partially reduced pyrimidine levels. …”
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    Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export
  2. 502
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    7-Chloro-5-(chloro­meth­yl)pyrazolo­[1,5-a]pyrimidine-3-carbonitrile
  3. 503
    por Lin, Cui-Hua, Liu, Nai-Sheng
    Publicado 2012
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    2-Amino-4,6-dimeth­oxy­pyrimidin-1-ium 2,2-dichloro­acetate
  4. 504
    por Gao, Guo-Rui, Duan, Wen-Hu
    Publicado 2012
    “…In the title compound, C(10)H(9)N(5), the fused 2-methyl­imidazo[1,2-a]pyrimidine ring system is approximately planar [dihedral angle of 1.14 (9)° between the two fused rings] and the 1H-pyrazole ring is rotated by 28.16 (11)° out of that plane. …”
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    2-Methyl-3-(1H-pyrazol-3-yl)imidazo[1,2-a]pyrimidine
  5. 505
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    Yields of damage to C4′ deoxyribose and to pyrimidines in pUC18 by the direct effect of ionizing radiation
  6. 506
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    3,5,6-Trimethyl­thieno[2,3-d]pyrimidin-4(3H)-one
  7. 507
    “…The asymmetric unit of the title compound, [Li(4)(C(6)H(2)N(2)O(4))(2)(H(2)O)(6)](n), comprises two Li(+) ions bridged by a completely deprotonated pyrimidine-3,6-dicarboxyl­ate ligand and coordinated by two water mol­ecules; the asymmetric units related by an inversion operation create a structural unit which forms part of a two-dimensional polymeric structure parallel to (10-1). …”
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    Poly[hexa­aqua­bis­(μ(4)-pyrimidine-4,6-dicarboxyl­ato)tetra­lithium]
  8. 508
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    Poly[[hexa­aqua­bis­(μ(3)-pyrimidine-4,6-dicarboxyl­ato)dicalcium] dihydrate]
  9. 509
    “…The mean plane of the central thio­urea fragment forms dihedral angles of 13.50 (14) and 5.03 (11)° with the furan and pyrimidine rings, respectively. The dihedral angle between the furan and pyrimidine rings is 18.43 (10)°. …”
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    3-[(Furan-2-yl)carbon­yl]-1-(pyrimi­din-2-yl)thio­urea
  10. 510
    “…The fused pyrazole and pyrimidine rings in the title compound, C(16)H(15)N(3)O(2), are almost coplanar, being inclined to one another by 1.31 (12)°. …”
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    Ethyl 7-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidine-5-carboxyl­ate
  11. 511
    “…The columns related by a unit translation along the b axis are packed into (100) layers via another C—H⋯π inter­action involving the pyrimidine ring as an acceptor.…”
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    2-{4-[(1,3-Benzodioxol-5-yl)meth­yl]piperazin-1-yl}pyrimidine
  12. 512
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    Co-Existence of Hereditary Pyrimidine 5’-Nucleotidase Deficiency and Heterozygous α-Thalassemia: A Case Presentation
  13. 513
    “…In the title compound, C(7)H(8)N(4)S, the methyl C atom is displaced by 1.232 (7) Å from the mean plane of the pyrazolo­[3,4-d]pyrimidine ring system (r.m.s. deviation = 0.007 Å). …”
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    Crystal structure of 1-ethyl­pyrazolo[3,4-d]pyrimidine-4(5H)-thione
  14. 514
    “…There has been special interest in the chemistry of quinolone and pyrimidine derivatives due to their diverse biological activities such as anticonvulsant, anti-malarial agents, antibacterial, antiviral, cytostatic, antithelemintic, antigenotoxic, anti-cancer agents. …”
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    Synthesis and Antimicrobial Activity of some Tetrahydro Quinolone Diones and Pyrano[2,3-d]pyrimidine Derivatives
  15. 515
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    Crystal structure of 4-methyl­sulfanyl-2-(2H-tetra­zol-2-yl)pyrimidine
  16. 516
    “…The reaction of 5-amino-N-aryl-1H-pyrazoles 4a–c with acetylacetone 5 or 2-(4-methoxybenzylidene)malononitrile 8 yielded the pyrazolo[1,5-a]pyrimidine derivatives 7a–c and 10a–c, respectively. …”
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    Synthesis, Characterization, and Cytotoxicity of Some New 5-Aminopyrazole and Pyrazolo[1,5-a]pyrimidine Derivatives
  17. 517
    por Ding, Yun, Kanavarioti, Anastassia
    Publicado 2016
    “…Osmylation is the addition of osmium tetroxide 2,2’-bipyridine (OsBp) to the C5–C6 pyrimidine double bond. The process is simple, selective for deoxythymidine (dT) over deoxycytidine (dC), unreactive towards the purines, practically 100% effective, and strikingly independent of length, sequence, and composition. …”
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    Single pyrimidine discrimination during voltage-driven translocation of osmylated oligodeoxynucleotides via the α-hemolysin nanopore
  18. 518
    “…On the other hand, thiazolo[3,2-a]pyrimidine-3-one 3 was coupled with aryldiazonium salts or condensed with isatin to afford compounds 4a–c or 5, respectively. …”
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    Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities
  19. 519
    “…Chemical compounds containing pyrimidine ring have been shown to regulate a variety of biological processes. …”
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    OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo
  20. 520
    “…Leishmania pyrimidine salvage is replete with opportunities for therapeutic intervention with enzyme inhibitors or antimetabolites. …”
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    Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy
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