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601
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602“…In the title compound, [Mn(2)(C(2)O(4))(C(5)H(3)N(2)O(2))(2)(H(2)O)(2)](n), the Mn(II) atom exhibits a distorted octahedral coordination geometry, with the centrosymmetric oxalate anion and the monoanionic pyrimidine-2-carboxylate ligands generating a two-dimensional honeycomb network with a (6,3)-topology.…”
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603
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604“…The asymmetric unit of the title compound, C(16)H(17)FN(2)O(4)S, contains three independent molecules, in which the pyrimidine and benzene rings are oriented at dihedral angles of 41.72 (3)°, 26.21 (3)° and 36.49 (3)°. …”
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605“…In the title compound, C(15)H(15)N(5)O(4)S, the dihedral angle between the pyrimidine and benzene rings is 84.56 (2)°. Intramolecular hydrazine–carbonyl N—H⋯O and intermolecular sulfonamide–pyridimine N—H⋯N hydrogen bonds stabilize the molecular and crystal structures, respectively.…”
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606por Neuenfeldt, Patrícia D., Drawanz, Bruna B., Cunico, Wilson, Tiekink, Edward R. T., Wardell, James L., Wardell, Solange M. S. V.“…The title compound, C(12)H(15)N(3)OS, features an envelope conformation for the 1,3-thiazolidin-4-one ring with the S atom as the flap atom. The pyrimidine ring is almost orthogonal to the 1,3-thiazolidin-4-one ring as indicated by the N—C—C—N torsion angle of −111.96 (18)°. …”
Publicado 2009
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607
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608“…Intramolecular π–π interactions between the pyrimidine rings [centroid–centroid distance = 3.654 (2) Å] and between the pyridine rings [centroid–centroid distance = 3.775 (2) Å] help to set the molecular conformation; the pyrimidine rings, as well as the pyridine rings, are nearly parallel, forming dihedral angles of 4.12 (14) and 2.46 (14)°, respectively.…”
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609“…In the title compound, C(14)H(14)ClN(3)OS, the 4,6-dimethylpyrimidine ring and the chlorobenzene ring subtend a dihedral angle of 80.0 (2)°. …”
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610
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611
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612por Jasinski, Jerry P., Butcher, Ray J., Hakim Al-Arique, Q. N. M., Yathirajan, H. S., Narayana, B.“…The dihedral angles of the pyrimidine ring with the benzene and pyridyl rings are 22.3 (1) and 53.2 (9)°, respectively, in molecule A, and 6.8 (1) and 11.6 (9)° in molecule B. …”
Publicado 2010
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613“…A new and facile synthesis of 2-thioxoquinazolin-4-ones by introducing a benzenoid system in the pyrimidine moiety by reacting ethoxymethylene derivatives of 1,3-diarylthiobarbituric acids (DTBA) with active methylene compounds, such as malononitrile and ethyl cyanoacetate, in presence of ZnCl(2) has been developed.…”
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614“…The molecule of the title perimidine derivative, C(18)H(12)N(2)O(3), is essentially planar, the dihedral angle between the benzene and perimidine rings being 3.25 (5)°. …”
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615“…Self-assembly of these dimeric units results in a four-component supramolecular unit featuring a homosynthon between two molecules of the pyrimidin-2-amine involving two N—H⋯O hydrogen bonds, and two heterosynthons between each one molecule of pyrimidin-2-amine and 1-phenylcyclopentane-1-carboxylic acid involving N—H⋯O and O—H⋯N hydrogen bonds.…”
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616por Redrejo-Rodríguez, Modesto, Saint-Pierre, Christine, Couve, Sophie, Mazouzi, Abdelghani, Ishchenko, Alexander A., Gasparutto, Didier, Saparbaev, Murat“…However little is known about repair of pyrimidine-derived hydantoins in human cells. METHODOLOGY/PRINCIPAL FINDINGS: Here, using both denaturing PAGE and MALDI-TOF MS analyses we report that the bacterial, yeast and human AP endonucleases can incise duplex DNA 5′ next to 5OH-Hyd and 5OH-5Me-Hyd thus initiating the NIR pathway. …”
Publicado 2011
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617“…The treatment with 5-FU can lead to severe toxicity due to enzyme deficiencies in the degradation of pyrimidines, but it can also lead to thiamine deficiency with the classic symptoms of beriberi. …”
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618“…In L, the pyridine and pyrimidine rings are twisted at an angle of 11.2 (1)°. …”
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619por Praveen, A. S., Jasinski, Jerry P., Golen, James A., Yathirajan, H. S., Narayana, B.“…In the title compound, C(15)H(17)N(3)O(3), the dihedral angle between the pyrimidine and benzene rings is 87.0 (7)°. In the crystal, molecules are linked into inversion dimers with R (2) (2)(8) graph-set motifs by a pair of N—H⋯O hydrogen bonds. …”
Publicado 2011
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620“…In the mononuclear title compound, [Ni(C(10)H(9)N(4)O(2)S)(2)(C(12)H(8)N(2))], the Ni(II) atom has a distorted octahedral coordination geometry comprising four N atoms from two 4-amino-N-(pyrimidin-2-yl)benzenesulfonamidate ligands and two N atoms from a 1,10-phenanthroline ligand. …”
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