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801
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802
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803por Xu, Shengzhen“…Adjacent thienophene–pyrimidine and pyrimidine–benzene rings have centroid–centroid distances of 3.96 (1) and 3.55 (2) Å, respectively.…”
Publicado 2007
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804por Tamazyan, Rafael, Ayvazyan, Armen, Martirosyan, Vahan, Avagyan, Kristine, Martirosyan, Ashot“…In the title compound, C(21)H(20)N(4)O(2), a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor, the pyrrolidine ring adopts an envelope conformation, while the hydrogenated pyrimidine ring adopts a weakly expressed twist conformation. …”
Publicado 2008
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805“…The angle at the methylene C atom linking the pyrimidine and cyclohexane ring is 113.7 (3)°, which is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibitors. …”
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806“…The asymmetric unit of the title compound, C(15)H(15)ClN(4)O(6)S, contains two independent molecules, in which the pyrimidine and benzene rings are oriented at dihedral angles of 75.21 (3) and 86.00 (3)°. …”
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807por Gaye, Papa Aly, Barry, Aliou Hamady, Gaye, Mohamed, Sarr, Aminata Diasse, Sall, Abdou Salam“…In the title compound, C(6)H(9)N(2)S(+)·Cl(−)·CH(4)N(2)S, the 4,6-dimethyl-2-thioxo-1,2-dihydropyrimidin-3-ium cation is protonated at one of the pyrimidine N atoms. …”
Publicado 2009
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808“…In the title compound, [Mn(C(11)H(8)N(3)O(2)S)(2)(H(2)O)(4)]·2H(2)O, the Mn(II) ion lies on an inversion centre and is coordinated by four water molecules in equatorial positions and two N atoms from two 2-[4-(3-pyridyl)pyrimidin-2-ylsulfanyl]acetate ligands in the axial positions. …”
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809por Hoffman, Jacqui E., Cheng, Henry, Rheingold, Arnold L., DiPasquale, Antonio, Yanovsky, Alex“…The title compound, C(12)H(19)BrN(4)O, represents the minor component of the two products obtained in a series of transformations involving the Grignard reaction of tert-butoxycarbonyl-protected 4-aminocyclohexanone with MeMgBr, and subsequent interaction of the obtained amino-substituted cyclohexanol with 4-chloro-6-methylpyrimidin-2-amine followed by bromination with N-bromosuccinimide. …”
Publicado 2009
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810
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811por Kannan, M., Manivel, P., Sarathbabu, M., Sathishkumar, R., Surya Prakash Rao, H., Krishna, R.“…In the title compound, C(19)H(22)N(4)O(2), the tetrahydropyrimidine ring adopts an envelope conformation (with the N atom connected to the benzyl group representing the flap). …”
Publicado 2010
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812“…The molecule is built up from two fused six-membered rings and one five-membered ring linked through a spiro C atom. Both the pyrimidine and the cyclopentane rings adopt envelope conformations. …”
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813
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814“…The dihedral angles formed by the two benzene rings with the pyrimidine ring are 70.70 (8) and 88.02 (9)°. The dihedral angle between two benzene rings is 46.67 (10)°.…”
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815por El-Moghazy, Samir M., Ibrahim, Diaa A., Abdelgawad, Nagwa M., Farag, Nahla A. H., El-Khouly, Ahmad S.“…A series of 2,5,7-trisubstituted pyrimido[4,5-d]pyrimidine cyclin-dependent kinase (CDK2) inhibitors is designed and synthesized. 6-Amino-2-thiouracil is reacted with an aldehyde and thiourea to prepare the pyrimido[4,5-d]-pyrimidines. …”
Publicado 2011
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816“…An N—H⋯O interaction occurs between the pyrimidine ring (donor) and carboxylate group (acceptor) while the other ring is formed by N—H⋯N interactions, which form a dimer between two symmetry-related salts. …”
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817“…In the title compound, C(18)H(17)N(5)O(2), the pyrimidine ring makes dihedral angles of 66.09 (12), 71.39 (13) and 56.7 (3)° with two phenyl rings and the nitro group, respectively. …”
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818“…In the title compound, C(11)H(9)N(5)O, the pyrazolopyrimidin-4-one ring system is almost planar, with a maximum deviation of 0.0546 (13) Å for the O atom. …”
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819por Pakawatchai, Chaveng, Wattanakanjana, Yupa, Choto, Patcharanan, Nimthong, Ruthairat“…In the mononuclear title complex, [CuI(C(6)H(8)N(2)S)(C(18)H(15)P)(2)], the Cu(I) ion is in a slightly distorted tetrahedral coordination geometry formed by two P atoms from two triphenylphosphane ligands, one S atom from a 4,6-dimethylpyrimidine-2(1H)-thione ligand and one iodide ion. There is an intramolecular N—H⋯I hydrogen bond. …”
Publicado 2012
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820por Khazi, Mohammed Iqbal A., Fathima, Nikhath, Belavagi, Ningaraddi S., Begum, Noor Shahina, Khazi, I. M.“…In the title compound, C(7)H(7)ClN(4)O, the pyrazolopyrimidine ring is essentially planar, the r.m.s. deviation of the fitted atoms being 0.0071 Å. …”
Publicado 2012
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