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1121“…An efficient, versatile, and one-pot method for the preparation of novel fluorinated thiazolo- and oxazolo[3,2-a]pyrimidin-7-ones is described from 2-aminothiazoles or 2-amino-oxazoles and fluorinated alkynoates. …”
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1122“…An efficient and general protocol for the synthesis of functionalized 2,4,6-triaryl pyridines and pyrimidines was developed from commercially available aromatic ketones, aldehydes and hexamethyldisilazane (HMDS) as a nitrogen source under microwave irradiation. …”
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1123por Bouihi, Fatiha, Schmaltz, Bruno, Mathevet, Fabrice, Kreher, David, Faure-Vincent, Jérôme, Yildirim, Ceren, Elhakmaoui, Ahmed, Bouclé, Johann, Akssira, Mohamed, Tran-Van, François, Abarbri, Mohamed“…The chemical structures of the molecules consist of a pyrazolo[1,5-a]pyrimidine acceptor core functionalized with one 3,6-bis(4,4′-dimethoxydiphenylamino)carbazole (3,6-CzDMPA) donor moiety via a phenyl π-spacer at the 3, 5 and 7 positions, respectively. …”
Publicado 2022
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1124“…The title compound, [Gd(C(5)H(2)N(2)O(4))(C(5)H(3)N(2)O(4))(C(12)H(8)N(2))(2)]·2H(2)O, was obtained from a solvothermal reaction of 2,4-dihydroxypyrimidine-5-carboxylic acid (H(3)iso), GdCl(3)·6H(2)O and 1,10-phenanthroline (phen). …”
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1125“…The title compound, 0.61C(19)H(17)BrN(4)O(3)S·0.39C(19)H(17)BrN(4)O(3)S, is a Schiff base derived from 5-bromosalicylaldehyde and 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide(sulfamethazine) and is isostructural with its chloro analogue. …”
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1126“…In the molecule of the title compound, C(24)H(20)F(2)N(6)O(4)·C(2)H(5)OH, the pyrimidine ring is oriented at dihedral angles of 42.64 (3) and 62.94 (3)° with respect to the benzene rings, while the dihedral angle between the benzene rings is 74.45 (3)°. …”
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1127por El-Kalyoubi, Samar, El-Sebaey, Samiha A., El-Sayed, Ahmed A., Abdelhamid, Moustafa S., Agili, Fatimah, Elfeky, Sherin M.“…Hence, novel series of pyrimidine Schiff bases (4–9) were employed in the synthesis of selenium nanoparticle forms (4NPs–9NPs). …”
Publicado 2023
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1128por Saleh, Abdulrahman M., Mahdy, Hazem A., El-Zahabi, Mohamed Ayman, Mehany, Ahmed B. M., Khalifa, Mohamed M., Eissa, Ibrahim H.“…A novel series of pyrimidine-5-carbonitrile derivatives bearing benzylidene and hydrazone moieties with different linkers (spacers) were designed and synthesized as possible inhibitors of the vascular endothelial growth factor receptor-2 (VEGFR-2). …”
Publicado 2023
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1129por Reda, Nada, Elshewy, Ahmed, EL-Askary, Hesham I., Mohamed, Khaled O., Helwa, Amira A.“…A novel series of pyrimidine-5-carbonitrile derivatives was designed, synthesized, then evaluated for their cytotoxic activity as novel anti-cancer with dual EGFR(WT)/COX-2 inhibitors. …”
Publicado 2023
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1130por Mansour, Basem, El-Sherbeny, Magda A., Al-Omary, Fatmah A. M., Saber, Sameh, Ramadan, Heba A., El-Baz, Ahmed M., Mourad, Ahmed A. E., Abdel-Aziz, Naglaa I.“…[Image: see text] Two hybrid series of pyrazole-clubbed pyrimidines 5a–c and pyrazole-clubbed pyrazoline compounds 6a,b and 7 were designed as attractive scaffolds to be investigated in vitro and in vivo for antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. …”
Publicado 2023
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1131por Mostafa, Sahar I., Papatriantafyllopoulou, Constantina, Perlepes, Spyros P., Hadjiliadis, Nick“…The new complexes [M(2)O(5)L(2)(H(2)O)(2)] · H(2)O (M = Mo, 1; M = W, 2), [RuL(2)(H(2)O)(2)] · H(2)O (3), [ML(3)] · xH(2)O (M = Rh, x = 2, 4; M = Ir, x = 1, 5), [RhL(2)(PPh(3))(2)](ClO(4)) · 2H(2)O (6), [PdL(2)] · 2H(2)O (7), [PdL(phen)]Cl · H(2)O (8), [Re OL(2)(PPh(3))]Cl (9) and [UO(2)L(2)] (10) are reported, where LH is 4,6-diamino-1-hydro-5-hydroxy-pyrimidine-2-thione. The complexes were characterized by elemental analyses, physical techniques (molar conductivity, room-temperature magnetic susceptibility), and spectroscopic (IR, Raman, UV/VIS/ligand field, NMR, mass) methods. …”
Publicado 2008
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1132
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1133“…The crystal structure consists of μ-N:N′ pyrimidine-bridged zigzag-like nickel thiocyanate chains; these are further linked by μ-N:N-bridging pyrimidine ligands into layers which are stacked perpendicular to the b axis. …”
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1134“…In the title compound, C(18)H(15)N(3)O(3)·0.5CH(2)Cl(2), the fused ring benzofuro[2,3-d]pyrimidine system is essentially planar [maximum deviation 0.029 (1) Å]. …”
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1135por Nayak, Susanta K., Venugopala, K. N., Chopra, Deepak, Govender, Thavendran, Kruger, Hendrik G., Maguire, Glenn E. M., Guru Row, T. N.“…In the title compound, C(14)H(15)ClN(2)O(2)S, the tetrahydropyrimidine ring adopts a twisted boat conformation with the carbonyl group in an s-trans conformation with respect to the C=C double bond of the six-membered tetrahydropyrimidine ring. …”
Publicado 2009
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1136
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1137“…In the title compound, C(19)H(23)Cl(2)N(3)OS, the dihedral angle between the benzene ring and the pyrimidine ring is 86.6 (9)°. The piperidine ring adopts a chair conformation.…”
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1138
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1139“…The asymmetric unit consists of one Co(II) ion, one pyrimidine ligand, two selenocyanate anions and one methanol molecule in general positions as well as one pyrimidine ligand located around a twofold rotation axis. …”
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1140