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“…In the title compound, C(14)H(15)BrN(2)O(3), the dihydro­pyrimidin­one ring adopts a boat conformation. In the crystal, adjacent mol­ecules are linked through N—H⋯O hydrogen bonds forming an R(2)(2)(8) ring motif and generating a zigzag chain extending in [010].…”
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“…A number of substituted-α,β-unsaturated carbonyl compounds (1a-i) were prepared by Claisen-Schmidt condensation of substituted acetophenone with selected araldehydes, which on cycloaddition with thiourea furnished 4,6-disubstituted pyrimidine-2-thiols (2a-i). Reaction of (2a-i) with ethyl chloroacetate followed by condensation with hydrazine hydrate yielded 2-[(4,6-disubstituted pyrimidine-2-yl) thio] acetohydrazides (4a-c). …”
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“…In the title complex, [PdBr(2)(C(13)H(18)N(2))(2)], the Pd(II) atom is situated on an inversion center. The tetra­hydro­pyrimidine group of the N-(2,4,6-trimethyl­phen­yl)-1,4,5,6-tetra­hydro­pyrimidine ligand is twisted from the square (PdN(2)Br(2)) coordination plane with a C—N—Pd—Br torsion angle of 81.8 (4)°; this is different from the angle of 43.47 (14)°, reported in a closely related structure, dichloridobis(1-methyl-1,4,5,6-tetra­hydro­pyrimidine)­palladium(II).…”
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“…The coordination environment is formed by two 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (dmtp) ligands, coordinated through the N atom in position 3, and two cyanate anions inter­acting by their N atoms. …”
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“…One is generated by the inter­action of the 2-amino-4,6-dimethyl­pyrimidin-1-ium cation with the carboxyl­ate group of the 2,3,5-triiodo­benzoate anion via N—H⋯O hydrogen bonds. …”
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“…New fluorescent compounds, benzo[4,5]thieno[3,2-d]pyrimidine 5,5-dioxides (3a–g), 2-amino-4-methylsulfanylbenzo[4,5]thieno[3,2-d]pyrimidine (6), and 2-amino-4-methylsulfanyl-7-methoxybenzo[4,5]furo[3,2-d]pyrimidine (7), were synthesized in good yields from heterocyclic ketene dithioacetals (1a–c) and guanidine carbonate (2a) or (S)-methylisothiourea sulfate (2b) in pyridine under reflux. …”
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“…In the title coordination polymer, [Hg(NCS)(2)(C(4)H(5)N(3))], the Hg(II) atom is four-coordinated by one aromatic N atom from a 2-amino­pyrimidine ligand, one S atom from a terminal thio­cyanate ligand, and one S atom and one N atom from a bridging thio­cyanate ligand. …”
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“…The polymeric chains are linked by C—H⋯O inter­actions and there are π–π inter­actions between the pyrimidine rings with a centroid–centroid distance of 3.446 (2) Å.…”
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“…The crystal structure also features inversion-generated aromatic π–π stacking inter­actions between the pyrimidine rings for both mol­ecules [centroid–centroid distances = 3.412 (2) (mol­ecule A) and 3.396 (2) Å (mol­ecule B)].…”
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“…In order to aid inhibitor design and rationalize the basis for CDK9 selectivity, we have studied the CDK-binding properties of six different members of a 4-(thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile series that bind to both CDK9/cyclin T and CDK2/cyclin A. …”
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“…In the title compound, C(24)H(18)Cl(4)N(4), the pyrimidine ring makes dihedral angles of 19.1 (2), 4.1 (2) and 67.5 (2)°, respectively, with phenyl and two benzene rings, and the mol­ecular conformation is stabilized by an intra­molecular N—H⋯N hydrogen bond closing a six-membered ring with an S(6) motif. …”
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“…PURPOSE: The present paper demonstrates the utility of PASS computer-aided program and makes a clear comparison of predicted and observed pharmacological properties of some novel 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2, 4, 6 (1H, 3H, 5H)-triones (5a–f). MATERIALS AND METHODS: The synthesis of the titled derivatives were achieved by the reaction between 2E)-1-(1H-benzimidazol-2-yl)-3-phenylprop-2-en-1-ones (4a–f) and barbituric acid in the presence of catalytic amount of acetic acid medium. …”
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“…The fused pyrazole and pyrimidine rings in the title compound, C(22)H(19)BrN(4)O, are almost coplanar, their planes being inclined to one another by 2.08 (13)°. …”
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“…Moreover, a novel route to pyrido[2,3-d]pyrimidine was achieved. Most of the synthesized compounds were found to exhibit strong inhibitory effects on the growth of Gram-positive bacteria especially Bacillus subtilis. …”
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“…Supra­molecular tapes along [1-10] are formed in the crystal packing through N(amino)—H⋯O(hydrox­yl) and N(amino)—H⋯N(pyrimidin­yl) hydrogen bonds, and these are linked into layers in the ab plane by π–π inter­actions [inter-centroid distance between pyrimidinyl rings = 3.5919 (9) Å].…”
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