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  1. 1461
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    1-[(1,3-Dithio­lan-2-yl)meth­yl]-8-nitro-6-propyl-1,2,3,5,6,7-hexa­hydro­imidazo[1,2-c]pyrimidine
  2. 1462
    por Li, Hai-Bo, Shi, Hai-Bo, Hu, Wei-Xiao
    Publicado 2011
    “…In the title compound, C(22)H(19)Cl(2)N(5)S, the thia­zole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°. …”
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    4-{2-[(3,4-Dichloro­phen­yl)(meth­yl)amino]-4-methyl-1,3-thia­zol-5-yl}-N-(3-methyl­phen­yl)pyrimidin-2-amine
  3. 1463
    por Shi, Hai-Bo, Li, Hai-Bo, Hu, Wei-Xiao
    Publicado 2011
    “…In one mol­ecule, the thia­zole and pyrimidine rings are almost co-planar, making a dihedral angle of 2.48 (8)°. …”
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    N-(3-Meth­oxy­phen­yl)-4-{4-methyl-2-[(meth­yl)(4-methyl­phen­yl)amino]-1,3-thia­zol-5-yl}pyrimidin-2-amine
  4. 1464
    “…The title complex, [NaRuCl(4)(C(4)H(4)N(2))(C(2)H(6)OS)(2)](n), is the sodium salt of monoanionic octa­hedral [Ru(III)Cl(4)(pyrimidine)(DMSO)](−) in which the sulfur-bound dimethyl sulfoxide (DMSO) and pyrimidine ligand are oriented trans to one another on the Ru(III) atom. …”
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    Poly[μ(3)-chlorido-μ(2)-chloridodichlorido(μ-dimethyl sulfoxide-κ(2) O:S)(dimethyl sulfoxide-κO)(μ-pyrimidine-κ(2) N:N′)­ruthenium(III)sodium]
  5. 1465
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    A second monoclinic polymorph of 6-amino-1,3-dimethyl-5-[(E)-2-(methyl­sulfan­yl)benzyl­idene­amino]­pyrimidine-2,4(1H,3H)-dione
  6. 1466
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    2-Amino­pyridinium 5-(5-chloro-2,4-dinitro­phen­yl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetra­hydro­pyrimidin-6-olate
  7. 1467
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    6-(3,5-Dimethyl­benz­yl)-5-ethyl-1-[(2-phen­oxy­eth­oxy)meth­yl]-1,2,3,4-tetra­hydro­pyrimidine-2,4-dione
  8. 1468
    por He, Ping, Wan, Qin-Qin, Liao, Quan-Lei
    Publicado 2012
    “…In the title compound, C(31)H(37)ClN(4)O(3), the fused rings of the pyrrolo­[3,2-d]pyrimidine system form a dihedral angle of 5.80 (11)°. …”
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    Ethyl 3-(4-chloro­phen­yl)-2-(dipentyl­amino)-4-oxo-5-phenyl-4,5-dihydro-3H-pyrrolo­[3,2-d]pyrimidine-7-carboxyl­ate
  9. 1469
    “…In the title compound, C(20)H(16)Cl(2)N(4)O(2), the dihedral angles between the planes of the chloro­phenyl, chloro­cyano­phenyl­imine and ester groups and the plane of the six-membered tetra­hydro­pyrimidine ring are 86.9 (2), 72.6 (2) and 7.9 (2)°, respectively. …”
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    Methyl (E)-2-[(3-chloro-4-cyano­phenyl)­imino]-4-(4-chloro­phen­yl)-6-methyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
  10. 1470
    “…The asymmetric unit of the title compound, C(19)H(19)N(3)O(4), contains two mol­ecules with very few conformational differences; a C atom in the pyrimidine ring in one of the mol­ecules is disordered in a 0.688 (15):0.312 (15) ratio. …”
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    [6-(Furan-2-yl)-7-nitro-2,3,4,6,7,8-hexa­hydro-1H-pyrido[1,2-a]pyrimidin-9-yl](phen­yl)methanone
  11. 1471
    “…The mercury coordination polyhedron can be described as tetra­hedral (from the N,N′-bidenate bi­pyridine mol­ecule and the sulfonamide N atoms of the sulfamerazine anions) or as squashed trigonal-prismatic, if two long (> 2.80 Å) Hg—N bonds to pyrimidine N atoms are included. The dihedral angle between the aromatic rings in the anion is 73.3 (2)°. …”
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    Bis[4-amino-N-(4-methyl­pyrimidin-2-yl-κN (3))benzene­sulfonamidato-κN](2,2′-bi­pyridine-κ(2) N,N′)mercury(II)
  12. 1472
    “…[Image: see text] Structure–activity relationships for cellular uptake and inhibition of cell proliferation were studied for 2-amino-4-oxo-6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolates in which the terminal l-glutamate of the parent structure (7) was replaced by natural or unnatural amino acids. …”
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    Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter
  13. 1473
    “…In the title compound, C(17)H(22)N(2)O(6), the di­hydro­pyrimidine ring adopts a flattened boat conformation. …”
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    Crystal structure of ethyl 6-methyl-2-oxo-4-(3,4,5-tri­meth­oxy­phen­yl)-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
  14. 1474
    “…In the title compound, C(20)H(16)Cl(2)N(2)O(2)S, the pyrimidine ring has a screw-boat conformation. The attached di­chloro­phenyl ring is twisted at an angle of 89.29 (13)° with respect to the pyrimidine ring mean plane. …”
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    Crystal structure of ethyl 4-(2,4-di­chloro­phen­yl)-2-methyl-4H-benzo[4,5]thia­zolo[3,2-a]pyrimidine-3-carboxyl­ate
  15. 1475
    “…CONCLUSIONS: In summary, new and efficient synthetic routes of isoxazoline, pyrrolo[3,4-d]isoxazole-4,6-dione derivatives, pyrazoles, pyrazolo[3,4-d]pyridazines and pyrazolo[1,5-a]pyrimidines have been achieved and the biological activity has been investigated. …”
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    Regioselectivity of 1,3-dipolar cycloadditions and antimicrobial activity of isoxazoline, pyrrolo[3,4-d]isoxazole-4,6-diones, pyrazolo[3,4-d]pyridazines and pyrazolo[1,5-a]pyrimidines
  16. 1476
    “…This study describes the design, synthesis and evaluation of 18 compounds incorporating a pyrrolo[2,3-d]pyrimidine scaffold for dual inhibition of epidermal growth factor receptor kinase (EGFR) and aurora kinase A (AURKA). …”
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    Design, synthesis and biological activity of N(4)-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kinase
  17. 1477
    “…Finally, compounds 12a,b were refluxed with dimethylformamide dimethylacetal (DMFDMA) to afford amidines 13a,b that were readily cyclized to the corresponding pyrazolo[4,3-d]pyrimidines 14a,b when refluxed with ammonium acetate.…”
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    Studies on 2-Arylhydrazononitriles: Synthesis of 3-Aryl-2-arylhydrazopropanenitriles and Their Utility as Precursors to 2-Substituted Indoles, 2-Substituted-1,2,3-Triazoles, and 1-Substituted Pyrazolo[4,3-d]pyrimidines
  18. 1478
    “…Analogously, the reactions of hydrazonoyl halides with 7-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-5-phenyl-2-thioxo-2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-one gave 3-(4-substituted)-8-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-6-phenyl-1-arylpyrido[2,3-d]-[1,2,4]-triazolo-[4,3-a]pyrimidin-5(1H)-ones in a good yield. …”
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    Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating Triazole Moiety
  19. 1479
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    Synthesis of novel thiazole, pyranothiazole, thiazolo[4,5-b]pyridines and thiazolo[5′,4′:5,6]pyrano[2,3-d]pyrimidine derivatives and incorporating isoindoline-1,3-dione group
  20. 1480
    “…Dialkylaminoalkylamides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids have been obtained as potential antiviral agents. …”
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    4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acids
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