“…The embryo of the sand-dollar (Echinarachnius parma) was exposed to various concentrations of fluorinated pyrimidines immediately after fertilization. FUDR (5-fluorodeoxyuridine) was most active, and a concentration of 2 to 4 mγ/10 cc. (0.8 to 1.6 x 10(-6) m.eq.…”
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“…METHODS: Two generally overlooked types of DNA damage, the formamide modification and the thymine glycol modification, both derived from pyrimidine bases, were assayed as markers of oxidative stress. …”
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“…To elucidate the contribution of pyrimidine in DNA strand breaks caused by low-energy electrons (LEEs), theoretical investigations of the LEE attachment-induced C(3′)–O(3′), and C(5′)–O(5′) σ bond as well as N-glycosidic bond breaking of 2′-deoxycytidine-3′,5′-diphosphate and 2′-deoxythymidine-3′,5′-diphosphate were performed using the B3LYP/DZP++ approach. …”
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“…The Zn(II) ion binds to two N atoms from two different 2-amino­pyrimidine ligands and two bromide ions. N—H⋯N hydrogen bonds link the mol­ecules to form a one-dimensional supra­molecular structure. …”
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“…In the title compound, C(7)H(14)N(6), the amine groups of the two methyl­hydrazino substituents are orientated in the opposite direction to the methyl substituent at the 2-position of the pyrimidine ring. The mol­ecule is almost planar with only the two amine N atoms lying substanti­ally out of the mean plane of the pyrimidine ring [by 0.1430 (2) and 0.3092 (2) Å]. …”
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“…The dimers are arranged into chains via inter­molecular N—H⋯N hydrogen bonds between the hydrazino groups and the N atoms of the pyrimidine rings of both types of the mol­ecules, linking the mol­ecules into a C(7) graph-set motif along [100]. …”
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“…In the aminal-type title compound, C(10)H(15)N(3), the six-membered hexa­hydro­pyrimidine ring adopts a chair conformation and the N atoms are pyramidally coordinated. …”
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“…In the title compound, C(15)H(19)N(3), the pyrimidine ring is approximately planar [maximum deviation = 0.007 (1) Å] and forms a dihedral angle of 3.15 (6)° with the benzene ring. …”
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“…The pyrimidin-4(3H)-one group is essentially planar, with a maximum deviation of 0.081 (1) Å for the O atom. …”
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“…The title compound, C(6)H(6)N(2)O(2)S, is a new polymorphic form of 2-(pyrimidin-2-ylsulfan­yl)acetic acid. Unlike the previous orthorhombic polymorph [Pan & Chen (2009 ▶) Acta Cryst. …”
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“…PYD1 (dihydropyrimidine dehydogenase) initiates the degradation of pyrimidine nucleobases and is located in plastids. In this study, a physiological analysis of PYD1 employing T-DNA knockout mutants and overexpressors was carried out. …”
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“…In the title compound, C(18)H(17)N(3), the dihedral angles between the central pyrimidine ring and its directly-bonded and N-bonded pendant phenyl rings are 25.48 (6) and 80.33 (6)°, respectively. …”
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“…In the title salt, C(4)H(5)ClN(3) (+)·C(4)H(3)O(4) (−), the 2-amino-5-chloro­pyrimidinium cation is protonated at one of its pyrimidine N atoms. In the roughly planar (r.m.s. deviation = 0.026 Å) hydrogen malate anion, an intra­molecular O—H⋯O hydrogen bond generates an S(7) ring. …”
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“…The title compound, C(6)H(4)ClN(3), is essentially planar with the pyrrole and pyrimidine rings inclined to one another by 0.79 (15)°. …”
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“…The title compound, C(10)H(16)N(4), crystalizes with two mol­ecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in one of the mol­ecules are disordered over two sets of sites with occupancy factors 0.508 (11):0.492 (11). …”
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“…In both independent mol­ecules in the asymmetric unit, the tricyclic perimidine consists of a planar (r.m.s. deviations = 0.0125 and 0.0181 Å) naphthalene ring system and an envelope conformation C(4)N(2) ringwith the NCN group hinged with respect to the naph­thalene backbone by 36.9 (2) and 41.3 (2)° in the two independent molecules. …”
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