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  1. 13181
    “…The findings of the present study indicate that AGR2 expression is significantly associated with location and size of GC, depth of invasion, TNM stage, lymphatic metastasis, vessel invasion, distant metastasis, Lauren's classification, high CTSD expression and poor prognosis. …”
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    AGR2 is associated with gastric cancer progression and poor survival
  2. 13182
    por Wilkins, Katie, Hassan, Mehedi, Francescatto, Margherita, Jespersen, Jakob, Parra, R. Gonzalo, Cuypers, Bart, DeBlasio, Dan, Junge, Alexander, Jigisha, Anupama, Rahman, Farzana, Laenen, Griet, Willems, Sander, Thorrez, Lieven, Moreau, Yves, Raju, Nagarajan, Chothani, Sonia Pankaj, Ramakrishnan, C., Sekijima, Masakazu, Gromiha, M. Michael, Slator, Paddy J, Burroughs, Nigel J, Szałaj, Przemysław, Tang, Zhonghui, Michalski, Paul, Luo, Oskar, Li, Xingwang, Ruan, Yijun, Plewczynski, Dariusz, Fiscon, Giulia, Weitschek, Emanuel, Ciccozzi, Massimo, Bertolazzi, Paola, Felici, Giovanni, Cuypers, Bart, Meysman, Pieter, Vanaerschot, Manu, Berg, Maya, Imamura, Hideo, Dujardin, Jean-Claude, Laukens, Kris, Domanova, Westa, Krycer, James R., Chaudhuri, Rima, Yang, Pengyi, Vafaee, Fatemeh, Fazakerley, Daniel J., Humphrey, Sean J., James, David E., Kuncic, Zdenka
    Publicado 2016
    “…Michael Gromiha O3 Detection of Heterogeneity in Single Particle Tracking Trajectories Paddy J Slator, Nigel J Burroughs O4 3D-NOME: 3D NucleOme Multiscale Engine for data-driven modeling of three-dimensional genome architecture Przemysław Szałaj, Zhonghui Tang, Paul Michalski, Oskar Luo, Xingwang Li, Yijun Ruan, Dariusz Plewczynski O5 A novel feature selection method to extract multiple adjacent solutions for viral genomic sequences classification Giulia Fiscon, Emanuel Weitschek, Massimo Ciccozzi, Paola Bertolazzi, Giovanni Felici O6 A Systems Biology Compendium for Leishmania donovani Bart Cuypers, Pieter Meysman, Manu Vanaerschot, Maya Berg, Hideo Imamura, Jean-Claude Dujardin, Kris Laukens O7 Unravelling signal coordination from large scale phosphorylation kinetic data Westa Domanova, James R. …”
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    Highlights from the 11th ISCB Student Council Symposium 2015: Dublin, Ireland. 10 July 2015
  3. 13183
    “…Univariate analysis indicated that age ≤ 50 years (P = 0.045), tumor invasion to the muscularis mucosa (P < 0.001), tumor size > 2 cm (P = 0.014), presence of ulceration (P = 0.01), diffuse type as per Lauren classification (P = 0.005), and undifferentiated-type histology (P = 0.001) were associated with LN metastasis. …”
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    Risk factors for lymph node metastasis in mucosal gastric cancer and re-evaluation of endoscopic submucosal dissection
  4. 13184
    “…METHODS: We examined genetic data from 3430 POAG cases and 3108 controls derived from the combination of the GLAUGEN and NEIGHBOR studies. We constructed biological-system coherent mitochondrial nuclear-encoded protein gene-sets by intersecting the MitoCarta database with the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. …”
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    Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses
  5. 13185
    “…No difference in ORR was observed in terms of gender, performance status, primary tumour site, gastric resection, histologic subtype, Lauren classification, No. of metastatic site and No. of chemotherapy. …”
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    To Excavate Biomarkers Predictive of the Response for Capecitabine plus RAD001 through Nanostring-Based Multigene Assay in Advanced Gastric Cancer Patients
  6. 13186
    “…Tumor size, lymphatic vessel or vein invasion, grading, classification systems (WHO, Lauren, Ming), expression of BAX, BCL-2, CDX2, Cyclin E, E-cadherin, Ki-67, TP53, TP21, SHH, Survivin, HIF1A, TROP2 and mismatch repair deficiency were analyzed using tissue microarrays and correlated with overall and tumor related survival. …”
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    Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas
  7. 13187
    “…Furthermore, high M2 TAMs density was correlated with larger tumor size, diffuse Lauren type, poor histologic differentiation, deeper tumor invasion, lymph node metastasis, and advanced TNM stage. …”
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    The Prognostic and Clinicopathological Significance of Tumor-Associated Macrophages in Patients with Gastric Cancer: A Meta-Analysis
  8. 13188
    “…Immune cell PD-L1 expression was frequently associated with intestinal type cancer by the Lauren classification (p = 0.015), with a lower risk of lymph node metastasis (p = 0.027) and lower tumor stages (p = 0.029) compared to MSI-H gastric cancers without PD-L1 expression. …”
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    Programmed cell death-ligand 1 expression predicts survival in patients with gastric carcinoma with microsatellite instability
  9. 13189
    “…BACKGROUND: Linitis plastica due to gastric adenocarcinoma is a condition with a long history, but still lacks a standardized definition and is commonly confused with Borrmann type IV, Lauren diffuse, and signet-cell type gastric cancer. …”
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    The significance of a nineteenth century definition in the era of genomics: linitis plastica
  10. 13190
    “…High Ki-67 expression was significantly related with Lauren's classification (OR = 1.70; P = 0.001; 95%CI: 1.40-2.06) and tumor size(OR = 1.54; P = 0.006; 95%CI: 1.14-2.09). …”
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    Clinicopathologic significance and prognostic value of Ki-67 expression in patients with gastric cancer: a meta-analysis
  11. 13191
    por Ye, Peng, Shi, Yu, Li, Anling
    Publicado 2018
    “…No association was found between hMLH1 promoter methylation and Lauren classification or Helicobacter pylori (HP) infection status. …”
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    Association Between hMLH1 Promoter Methylation and Risk of Gastric Cancer: A Meta-Analysis
  12. 13192
    “…RESULTS: The expression level of LIMD1 positively correlated with the prognosis of GC patients regardless of tumor stage, size, lymph node, metastasis, Lauren’s classification, differentiation, gender, treatment, and ERBB2 amplification status. …”
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    LIMD1 is a survival prognostic marker of gastric cancer and hinders tumor progression by suppressing activation of YAP1
  13. 13193
    “…Increased Uba2 expression was correlated with tissue differentiation, Lauren’s classification, vascular invasion, and TNM stage, as determined by the analysis of 100 GC cases (P < 0.05). …”
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    Ubiquitin-like modifier activating enzyme 2 promotes cell migration and invasion through Wnt/β-catenin signaling in gastric cancer
  14. 13194
    “…In multivariate analysis of disease-free survival, SPC-prognosis [hazard ratio (HR): 1.879 (1.101–3.205), 2.399 (1.415–4.067), p=0.003] and MSI status (HR: 0.363, 95% confidence interval: 0.161–0.820, p=0.015) were independent prognostic factors along with age, Lauren classification, TNM stage, and chemotherapy. …”
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    Single Patient Classifier Assay, Microsatellite Instability, and Epstein-Barr Virus Status Predict Clinical Outcomes in Stage II/III Gastric Cancer: Results from CLASSIC Trial
  15. 13195
    “…TMB was also significantly associated with DNA damage repair (DDR) genes genotype (p = 0.047), Lauren classification (p = 1.5e−5), differentiation (1.9e−7), and HER2 status (p = 0.023). 38.31% of gastric cancer patients harbored at least one actionable alteration according to OncoKB database. …”
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    Mutational landscape of gastric cancer and clinical application of genomic profiling based on target next-generation sequencing
  16. 13196
    por Zhang, Zhili, Zhu, Xiaoyong
    Publicado 2019
    “…LPA2 positive expression was associated with tumor invasion depth, Lauren type, vascular invasion, local lymph node metastasis, and clinical stage (P<0.05). …”
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    Clinical Significance of Lysophosphatidic Acid Receptor-2 (LPA2) and Krüppel-Like Factor 5 (KLF5) Protein Expression Detected by Tissue Microarray in Gastric Adenocarcinoma
  17. 13197
    “…According to univariate analysis, location, gross type, World Health Organization classification, Lauren classification, size, depth of invasion, and lymphatic invasion were significant variables affecting (18)F-FDG uptake (all P < .05). …”
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    Clinicopathologic parameters associated with the FDG-avidity in staging of early gastric cancer using (18)F-FDG PET
  18. 13198
    “…High expression of CDK12 was identified in 43 cases (50%), and it was significantly correlated with Lauren's classification (diffuse type) and number of metastatic lymph nodes (≥15). …”
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    Expression pattern of CDK12 protein in gastric cancer and its positive correlation with CD8(+) cell density and CCL12 expression
  19. 13199
    “…CLDN18.2 expression was significantly higher in GCs of the diffuse histological subtype per Lauren classification and in high grade (G3) tumors. …”
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    Comparison of Claudin 18.2 expression in primary tumors and lymph node metastases in Japanese patients with gastric adenocarcinoma
  20. 13200
    “…We will focus on different aspects including aggressiveness assessment, staging and Lauren type discrimination, prognosis prediction and response evaluation. …”
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    Gastric cancer and image-derived quantitative parameters: Part 2—a critical review of DCE-MRI and (18)F-FDG PET/CT findings
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