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221por Stavros, Sofoklis, Papapanagiotou, Ioannis K., Zacharakis, Dimitrios, Migklis, Kyriaki, Mantzioros, Rafail, Domali, Ekaterini, Chatzipapas, Ioannis, Drakakis, Peter, Rodolakis, Alexandros“…Neglected severe obstetric anal sphincter injuries may result in fecal incontinence. …”
Publicado 2021
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222“…OBJECTIVE: To analyze the therapeutic effect of Compound Phellodendron decoction on wounds after anal fistulotomy. METHODS: 100 patients with anal fistula who underwent anal fistulotomy from April 2019 to April 2021 were included in the study group and control group according to the random number table method. 50 patients in the study group were treated with Compound Phellodendron decoction by fumigation and sitting bath, while warm water replaced Compound Phellodendron decoction in the control group. …”
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223por Jones, Angharad, Ferrari, Linda, Martinez, Paula Igualada, Oteng-Ntim, Eugene, Hainsworth, Alison, Schizas, Alexis“…INTRODUCTION AND HYPOTHESIS: Obstetric anal sphincter injuries (OASIS) are a common cause of maternal morbidity with an overall incidence in the UK of 2.9% (range 0–8%). …”
Publicado 2021
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224“…The hallmark feature of the disease is severe pain during defecation. Chronic anal fissure (CAF) causes undue stress that leads to poor quality of life. …”
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226“…This de novo expression of PNAd correlates strongly with induction of transcripts for both GlcNAc6ST-1 and GlcNAc6ST-2, as well as the expression of GlcNAc6ST-2 protein. …”
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227por Mo, Delin, Zhu, Zhengmao, te Pas, Marinus FW, Li, Xinyun, Yang, Shulin, Wang, Heng, Wang, Huanling, Li, Kui“…RESULTS: We cloned the full-length cDNA of porcine PNAS-4 gene encoding a protein of 194 amino acids which was expressed in the Golgi complex. …”
Publicado 2008
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228por Onyshchenko, Mykola I., Gaynutdinov, Timur I., Englund, Ethan A., Appella, Daniel H., Neumann, Ronald D., Panyutin, Igor G.“…Using a DMS protection assay, we demonstrated G-quadruplex formation within the G-rich sequence from the promoter region of the human BCL2 gene in plasmid DNA. Our results show that molecules binding the complementary C-strand facilitate G-quadruplex formation and introduce a new mode of PNA-mediated sequence-specific targeting.…”
Publicado 2009
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230por McNeer, Nicole Ali, Anandalingam, Kavitha, Fields, Rachel J., Caputo, Christina, Kopic, Sascha, Gupta, Anisha, Quijano, Elias, Polikoff, Lee, Kong, Yong, Bahal, Raman, Geibel, John P, Glazer, Peter M., Saltzman, W. Mark, Egan, Marie E.“…Here, we use triplex-forming PNA molecules and donor DNA in biodegradable polymer nanoparticles to correct F508del. …”
Publicado 2015
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231por Yung, Tung-Yuan, Liu, Ting-Yu, Huang, Li-Ying, Wang, Kuan-Syun, Tzou, Huei-Ming, Chen, Po-Tuan, Chao, Chi-Yang, Liu, Ling-Kang“…Nanocomposite materials of the Au nanoparticles (Au/PDDA-G) and the bimetallic PtAu nanoparticles on poly-(diallyldimethylammonium chloride) (PDDA)-modified graphene sheets (PtAu/PDDA-G) were prepared with hydrothermal method at 90 °C for 24 h. …”
Publicado 2015
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233por Mengue, Sotero Serrate, Bertoldi, Andréa Dâmaso, Boing, Alexandra Crispim, Tavares, Noemia Urruth Leão, Pizzol, Tatiane da Silva Dal, Oliveira, Maria Auxiliadora, Arrais, Paulo Sérgio Dourado, Ramos, Luiz Roberto, Farias, Mareni Rocha, Luiza, Vera Lucia, Bernal, Regina Tomie Ivata, de Barros, Aluísio Jardim Dornellas“…OBJECTIVE: To describe methodological aspects of the household survey National Survey on Access, Use and Promotion of Rational Use of Medicines (PNAUM) related to sampling design and implementation, the actual obtained sample, instruments and fieldwork. …”
Publicado 2016
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234por Leite, Silvana Nair, Manzini, Fernanda, Álvares, Juliana, Guerra, Augusto Afonso, Costa, Ediná Alves, Acurcio, Francisco de Assis, Guibu, Ione Aquemi, Costa, Karen Sarmento, Karnikowski, Margô Gomes de Oliveira, Soeiro, Orlando Mário, Farias, Mareni Rocha“…METHODS: This is a cross-sectional study, of quantitative approach, from data obtained in the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos – Serviços, 2015 (PNAUM – National Survey on Access, Use and Promotion of Rational Use of Medicines – Services, 2015). …”
Publicado 2017
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235“…After optimization of the β‐PNA solid‐phase peptide synthesis and validation of helix formation, the ability of the novel β‐PNAs to dimerize and interact with lipid bilayers was investigated by both fluorescence and circular dichroism spectroscopy. …”
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236“…A pneumococcal immunization campaign was designed to address barriers and increase vaccine uptake from independent community pharmacies. METHODS: A “Did You Pneu?” pneumococcal immunization campaign was developed by a pharmacist at the head office of an independent community pharmacy banner. …”
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237por Peng, Wenjun, Wu, Yuanyuan, Zhang, Ge, Zhu, Wensi, Chang, Meijia, Rouzi, Ainiwaer, Jiang, Weipeng, Tong, Lin, Wang, Qin, Liu, Jie, Song, Yuanlin, Li, Huayin, Li, Ka, Zhou, Jian“…CONCLUSION: To conclude, GLIPR1 played a pivotal role in COPD pathogenesis and protected against CS-induced inflammatory response and airway damage, including cell pyroptosis, through the PLAU/EGFR signaling. …”
Publicado 2021
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238por Gaweda-Walerych, Katarzyna, Sitek, Emilia J., Borczyk, Małgorzata, Berdyński, Mariusz, Narożańska, Ewa, Brockhuis, Bogna, Korostyński, Michał, Sławek, Jarosław, Zekanowski, Cezary“…Successful rescue of PLAU mRNA levels by nonsense-mediated mRNA decay (NMD) inhibitor (puromycin) confirmed NMD as the underlying mechanism. …”
Publicado 2021
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240por Abes, Saïd, Turner, John J., Ivanova, Gabriela D., Owen, David, Williams, Donna, Arzumanov, Andrey, Clair, Philippe, Gait, Michael J., Lebleu, Bernard“…It requires sequence-specific and high affinity binding of RNaseH-incompetent DNA mimics to pre-mRNA. Peptide nucleic acids (PNA) or phosphoramidate morpholino oligonucleotides (PMO) are particularly suited as steric block oligonucleotides in this respect. …”
Publicado 2007
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