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121por Elskens, Joke, Manicardi, Alex, Costi, Valentina, Madder, Annemieke, Corradini, Roberto“…Over the past decades, peptide nucleic acid/DNA (PNA:DNA) duplex stability has been improved via backbone modification, often achieved via introducing an amino acid side chain at the α- or γ-position in the PNA sequence. …”
Publicado 2017
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122por Bannenberg, Lars Johannes, Nugroho, Ferry Anggoro Ardy, Schreuders, Herman, Norder, Ben, Trinh, Thu Trang, Steinke, Nina-Juliane, van Well, Ad A., Langhammer, Christoph, Dam, Bernard“…In response, for the case of Pd(1–y)Au(y) (y = 0.15–0.30) alloys, we directly compare these two systems and establish that they are distinctively different. …”
Publicado 2019
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123por Li, Zhexuan, Chen, Changhan, Wang, Juncheng, Wei, Ming, Liu, Guancheng, Qin, Yuexiang, She, Li, Liu, Yong, Huang, Donghai, Tian, Yongquan, Zhu, Gangcai, Zhang, Xin“…GO and PPI network were established on PLAU-related downstream molecular. The stroma score was deconvoluted for analysis of PLAU’s association with the immune environment. …”
Publicado 2021
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124por Iacono, Diego, Murphy, Erin K., Avantsa, Soundarya S., Perl, Daniel P., Day, Regina M.“…Our data show that radiated-animals had lower levels of pTau in FC and H, APP in H and CRB, GAP43 in CRB, and higher level of GFAP in H versus sham-animals. …”
Publicado 2021
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125por Tissot, Cécile, L. Benedet, Andréa, Therriault, Joseph, Pascoal, Tharick A., Lussier, Firoza Z., Saha-Chaudhuri, Paramita, Chamoun, Mira, Savard, Melissa, Mathotaarachchi, Sulantha S., Bezgin, Gleb, Wang, Yi-Ting, Fernandez Arias, Jaime, Rodriguez, Juan Lantero, Snellman, Anniina, Ashton, Nicholas J., Karikari, Thomas K., Blennow, Kaj, Zetterberg, Henrik, De Villers-Sidani, Etienne, Huot, Philippe, Gauthier, Serge, Rosa-Neto, Pedro“…BACKGROUND: To investigate the association of plasma pTau181, assessed with a new immunoassay, with neurodegeneration of white matter and gray matter cross-sectionally and longitudinally, in aging and Alzheimer’s disease. …”
Publicado 2021
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126por Wu, Min, Wei, Bo, Duan, Sai-Li, Liu, Mian, Ou-Yang, Deng-Jie, Huang, Peng, Chang, Shi“…Purpose: Aberrant DNA methylation plays a crucial role in the tumorigenesis of differentiated thyroid cancer (DTC); nevertheless, the factors leading to the local and regional recurrence of DTC are not well understood. …”
Publicado 2022
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127por Montes-Vergara, José Carlos, Penitente-Filho, Jurandy Mauro, Machado-Neves, Mariana, Machado, Lucas Corrêa Martins, Castaño-Villadiego, Faider Alberto, Costa, Karine Assis, da Costa, Eduardo Paulino, de Campos, Carolina Filardi, Ramírez-López, Camilo José, Guimarães, Simone Eliza Facioni, Lopes, Paulo Sávio, Guimarães, José Domingos“…ABSTRACT: This study aimed to evaluate the endometrial angiogenesis of pregnant commercial line and Piau gilts during early pregnancy. We used 27 gilts, divided into three groups according to the type of mating: Commercial (n = 9), commercial line females mated with commercial line males; Cross-mated (n = 9), Piau females mated with commercial line males; and Piau (n = 9), Piau females mated with Piau males. …”
Publicado 2022
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128“…In this work, a palladium binding peptide, Pd4, has been used for the synthesis of catalytically active palladium-decorated gold (Pd-on-Au) nanoparticles (NPs) and palladium–gold (Pd(x)Au(100−x)) alloy NPs exhibiting high nitrite degradation efficiency. …”
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129“…Here we take an extensive investigation of the evolution of keywords among all publications in PNAS Social Sciences from 1990 to 2021. Statistical tests show the keyword mention time series always accompanied by the emergence of a log-normal distribution. …”
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130por Mosseri, Andrea, Sancho-Albero, María, Mercurio, Flavia Anna, Leone, Marilisa, De Cola, Luisa, Romanelli, Alessandra“…In this work, we explored the self-assembly of PNA dimers conjugated to the dipeptide WW. Our studies suggest that the indole ring of tryptophan promotes aggregation of the conjugates. …”
Publicado 2023
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131por Potenza, Nicoletta, Moggio, Loredana, Milano, Giovanna, Salvatore, Vincenzo, Di Blasio, Benedetto, Russo, Aniello, Messere, Anna“…We demonstrate that the chemical modifications are compatible with the siRNA machinery, because all the PNA-modified siRNAs can efficiently mediate specific gene silencing in mammalian cells. …”
Publicado 2008
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133por Iverson, Douglas, Serrano, Crystal, Brahan, Ann Marie, Shams, Arik, Totsingan, Filbert, Bell, Anthony J.“…These data compare the electrophoretic mobility of hybrid PNA–DNA junctions vs. i) a classic immobile DNA 4WJ, J1 and ii) contaminating nucleic acid structures.…”
Publicado 2015
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134por Jaehme, Michael, Singh, Rajkumar, Garaeva, Alisa A., Duurkens, Ria H., Slotboom, Dirk-Jan“…For example, the PnuT transporters have specificity for vitamin B1 (thiamine). …”
Publicado 2018
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135por Veerbeek, Janneke, Steen, Raymond, Vijselaar, Wouter, Rurup, W. Frederik, Korom, Saša, Rozzi, Andrea, Corradini, Roberto, Segerink, Loes, Huskens, Jurriaan“…Although both functionalization routes were successful, hybridization could only be detected on the samples with thiol-PNA. No fluorescence was observed when introducing dye-labeled noncomplementary DNA, which indicates specific DNA hybridization. …”
Publicado 2018
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136por Canady, Taylor D., Berlyoung, April S., Martinez, Joe A., Emanuelson, Cole, Telmer, Cheryl A., Bruchez, Marcel P., Armitage, Bruce A.“…High affinity nucleic acid analogues such as gammaPNA (γPNA) are capable of invading stable secondary and tertiary structures in DNA and RNA targets but are susceptible to off-target binding to mismatch-containing sequences. …”
Publicado 2020
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137“…Importantly, we show that strand displacement from PNA–DNA heteroduplexes is compatible with RNA inputs, the most common nucleic acid target for intracellular applications. …”
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138por Sousa, Lúcia G. V., Castro, Joana, França, Angela, Almeida, Carina, Muzny, Christina A., Cerca, Nuno“…This work aims to develop a novel peptide nucleic acid (PNA) probe targeting F. vaginae. This probe was further validated in a multiplex assay, which included a Gardnerella-specific PNA probe, as a possible method for diagnosis of BV, and was compared with quantification by qPCR. …”
Publicado 2021
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139por Asefifeyzabadi, Narges, Durocher, Grace, Tshilenge, Kizito-Tshitoko, Alam, Tanimul, Ellerby, Lisa M., Shamsi, Mohtashim H.“…We present a PNA microprobe sensing platform to detect trinucleotide repeat mutation by electrochemical impedance spectroscopy. …”
Publicado 2022
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140por Capasso, Paola, Cimmino, Lucia, Abate, Andrea F., Bruno, Andrea, Cattaneo, Giuseppe“…A well-known Source Camera Identification (SCI) technique, based on Pixel Non-Uniformity (PNU), was applied to analyze the integrity of the input video stream as well as to detect any tampered/fake frames. …”
Publicado 2022
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