Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity

por Ji, Xia, Zou, Jin, Peng, Haibo, Stolle, Anne-Sophie, Xie, Ruiqiang, Zhang, Hongjie, Peng, Bo, Mekalanos, John J., Zheng, Jun
Publicado 2019

Data gaps and opportunities for comparative and conservation biology

por Conde, Dalia A., Staerk, Johanna, Colchero, Fernando, da Silva, Rita, Schöley, Jonas, Baden, H. Maria, Jouvet, Lionel, Fa, John E., Syed, Hassan, Jongejans, Eelke, Meiri, Shai, Gaillard, Jean-Michel, Chamberlain, Scott, Wilcken, Jonathan, Jones, Owen R., Dahlgren, Johan P., Steiner, Ulrich K., Bland, Lucie M., Gomez-Mestre, Ivan, Lebreton, Jean-Dominique, González Vargas, Jaime, Flesness, Nate, Canudas-Romo, Vladimir, Salguero-Gómez, Roberto, Byers, Onnie, Berg, Thomas Bjørneboe, Scheuerlein, Alexander, Devillard, Sébastien, Schigel, Dmitry S., Ryder, Oliver A., Possingham, Hugh P., Baudisch, Annette, Vaupel, James W.
Publicado 2019

The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity

por Barnes, Christopher O., Wu, Ying, Song, Jinhu, Lin, Guowu, Baxter, Elizabeth L., Brewster, Aaron S., Nagarajan, V., Holmes, Andrew, Soltis, S. Michael, Sauter, Nicholas K., Ahn, Jinwoo, Cohen, Aina E., Calero, Guillermo
Publicado 2019

Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane

por Wang, Qi, Pechersky, Yakov, Sagawa, Shiori, Pan, Albert C., Shaw, David E.
Publicado 2019

Overlooked roles of DNA damage and maternal age in generating human germline mutations

por Gao, Ziyue, Moorjani, Priya, Sasani, Thomas A., Pedersen, Brent S., Quinlan, Aaron R., Jorde, Lynn B., Amster, Guy, Przeworski, Molly
Publicado 2019

Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration

por Li, Dongqing, Kular, Lara, Vij, Manika, Herter, Eva K., Li, Xi, Wang, Aoxue, Chu, Tongbin, Toma, Maria-Alexandra, Zhang, Letian, Liapi, Eleni, Mota, Ana, Blomqvist, Lennart, Sérézal, Irène Gallais, Rollman, Ola, Wikstrom, Jakob D., Bienko, Magda, Berglund, David, Ståhle, Mona, Sommar, Pehr, Jagodic, Maja, Landén, Ning Xu
Publicado 2019

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance

por Lim, Jonathan K. M., Delaidelli, Alberto, Minaker, Sean W., Zhang, Hai-Feng, Colovic, Milena, Yang, Hua, Negri, Gian Luca, von Karstedt, Silvia, Lockwood, William W., Schaffer, Paul, Leprivier, Gabriel, Sorensen, Poul H.
Publicado 2019

Cystine–glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity

por Arensman, Michael D., Yang, Xiaoran S., Leahy, Danielle M., Toral-Barza, Lourdes, Mileski, Mary, Rosfjord, Edward C., Wang, Fang, Deng, Shibing, Myers, Jeremy S., Abraham, Robert T., Eng, Christina H.
Publicado 2019

HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells

por Yan, Junpeng, Shun, Ming-Chieh, Zhang, Yi, Hao, Caili, Skowronski, Jacek
Publicado 2019

Systematic assessment of the sex ratio at birth for all countries and estimation of national imbalances and regional reference levels

por Chao, Fengqing, Gerland, Patrick, Cook, Alex R., Alkema, Leontine
Publicado 2019

Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

por Uyehara, Christopher M., McKay, Daniel J.
Publicado 2019

Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis

por Voskuhl, Rhonda R., Itoh, Noriko, Tassoni, Alessia, Matsukawa, Macy Akiyo, Ren, Emily, Tse, Vincent, Jang, Ellis, Suen, Timothy Takazo, Itoh, Yuichiro
Publicado 2019

Retinal microglia initiate neuroinflammation in ocular autoimmunity

por Okunuki, Yoko, Mukai, Ryo, Nakao, Takeshi, Tabor, Steven J., Butovsky, Oleg, Dana, Reza, Ksander, Bruce R., Connor, Kip M.
Publicado 2019

Optogenetic fMRI interrogation of brain-wide central vestibular pathways

por Leong, Alex T. L., Gu, Yong, Chan, Ying-Shing, Zheng, Hairong, Dong, Celia M., Chan, Russell W., Wang, Xunda, Liu, Yilong, Tan, Li Hai, Wu, Ed X.
Publicado 2019

An oscillator model better predicts cortical entrainment to music

por Doelling, Keith B., Assaneo, M. Florencia, Bevilacqua, Dana, Pesaran, Bijan, Poeppel, David
Publicado 2019

Defining the core essential genome of Pseudomonas aeruginosa

por Poulsen, Bradley E., Yang, Rui, Clatworthy, Anne E., White, Tiantian, Osmulski, Sarah J., Li, Li, Penaranda, Cristina, Lander, Eric S., Shoresh, Noam, Hung, Deborah T.
Publicado 2019

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses

por Dodonova, Svetlana O., Prinz, Simone, Bilanchone, Virginia, Sandmeyer, Suzanne, Briggs, John A. G.
Publicado 2019

PD-1(+) regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

por Kamada, Takahiro, Togashi, Yosuke, Tay, Christopher, Ha, Danbee, Sasaki, Akinori, Nakamura, Yoshiaki, Sato, Eiichi, Fukuoka, Shota, Tada, Yasuko, Tanaka, Atsushi, Morikawa, Hiromasa, Kawazoe, Akihito, Kinoshita, Takahiro, Shitara, Kohei, Sakaguchi, Shimon, Nishikawa, Hiroyoshi
Publicado 2019

Dynamic cluster formation determines viscosity and diffusion in dense protein solutions

por von Bülow, Sören, Siggel, Marc, Linke, Max, Hummer, Gerhard
Publicado 2019

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

por Sarker, Gitalee, Sun, Wenfei, Rosenkranz, David, Pelczar, Pawel, Opitz, Lennart, Efthymiou, Vissarion, Wolfrum, Christian, Peleg-Raibstein, Daria
Publicado 2019