Loss of AMP-activated protein kinase α2 subunit in mouse β-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

por Beall, Craig, Piipari, Kaisa, Al-Qassab, Hind, Smith, Mark A., Parker, Nadeene, Carling, David, Viollet, Benoit, Withers, Dominic J., Ashford, Michael L. J.
Publicado 2010

Role of conservative mutations in protein multi-property adaptation

por Rodriguez-Larrea, David, Perez-Jimenez, Raul, Sanchez-Romero, Inmaculada, Delgado-Delgado, Asuncion, Fernandez, Julio M., Sanchez-Ruiz, Jose M.
Publicado 2010

The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants

por Churko, Jared M., Langlois, Stephanie, Pan, Xinyue, Shao, Qing, Laird, Dale W.
Publicado 2010

Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP

por Ramos, Isabela B., Miranda, Kildare, Pace, Douglas A., Verbist, Katherine C., Lin, Fu-Yang, Zhang, Yonghui, Oldfield, Eric, Machado, Ednildo A., De Souza, Wanderley, Docampo, Roberto
Publicado 2010

Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells

por Evans, Ian M., Bagherzadeh, Azadeh, Charles, Mark, Raynham, Tony, Ireson, Chris, Boakes, Alexandra, Kelland, Lloyd, Zachary, Ian C.
Publicado 2010

Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK p...

por Tchaparian, Eskouhie, Marshal, Lisa, Cutler, Gene, Bauerly, Kathryn, Chowanadisai, Winyoo, Satre, Michael, Harris, Calliandra, Rucker, Robert B.
Publicado 2010

Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by r...

por Chouchani, Edward T., Hurd, Thomas R., Nadtochiy, Sergiy M., Brookes, Paul S., Fearnley, Ian M., Lilley, Kathryn S., Smith, Robin A. J., Murphy, Michael P.
Publicado 2010

Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal

por Kaur, Gurpreet, Delluc-Clavieres, Aurelie, Poon, Ivan K. H., Forwood, Jade K., Glover, Dominic J., Jans, David A.
Publicado 2010

The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophage...

por Lane, Amanda E., Tan, Joanne T. M., Hawkins, Clare L., Heather, Alison K., Davies, Michael J.
Publicado 2010

Significance of serum adiponectin levels in patients with chronic liver disease

por Balmer, Maria Luisa, Joneli, Jeannine, Schoepfer, Alain, Stickel, Felix, Thormann, Wolfgang, Dufour, Jean-François
Publicado 2010

Bimolecular fluorescence complementation analysis of eukaryotic fusion products

por Lin, Ho-Pi, Vincenz, Claudius, Eliceiri, Kevin W., Kerppola, Tom K., Ogle, Brenda M.
Publicado 2010

Gene expression profiling in whole blood of patients with coronary artery disease

por Taurino, Chiara, Miller, William H., McBride, Martin W., McClure, John D., Khanin, Raya, Moreno, María U., Dymott, Jane A., Delles, Christian, Dominiczak, Anna F.
Publicado 2010

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

por Recino, Asha, Sherwood, Victoria, Flaxman, Amy, Cooper, Wendy N., Latif, Farida, Ward, Andrew, Chalmers, Andrew D.
Publicado 2010

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

por Nichols, R. Jeremy, Dzamko, Nicolas, Morrice, Nicholas A., Campbell, David G., Deak, Maria, Ordureau, Alban, Macartney, Thomas, Tong, Youren, Shen, Jie, Prescott, Alan R., Alessi, Dario R.
Publicado 2010

Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit

por Blackburn, Christopher, Gigstad, Kenneth M., Hales, Paul, Garcia, Khristofer, Jones, Matthew, Bruzzese, Frank J., Barrett, Cynthia, Liu, Jane X., Soucy, Teresa A., Sappal, Darshan S., Bump, Nancy, Olhava, Edward J., Fleming, Paul, Dick, Lawrence R., Tsu, Christopher, Sintchak, Michael D., Blank, Jonathan L.
Publicado 2010

SENP1 participates in the dynamic regulation of Elk-1 SUMOylation

por Witty, James, Aguilar-Martinez, Elisa, Sharrocks, Andrew D.
Publicado 2010

Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform

por Wang, Minchuan, Bond, Nicholas J., Letcher, Andrew J., Richardson, Jonathan P., Lilley, Kathryn S., Irvine, Robin F., Clarke, Jonathan H.
Publicado 2010

Evidence for an interaction between Golli and STIM1 in store-operated calcium entry

por Walsh, Ciara M., Doherty, Mary K., Tepikin, Alexei V., Burgoyne, Robert D.
Publicado 2010

Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle

por Vichaiwong, Kanokwan, Purohit, Suneet, An, Ding, Toyoda, Taro, Jessen, Niels, Hirshman, Michael F., Goodyear, Laurie J.
Publicado 2010

Electron capture dissociation mass spectrometric analysis of lysine-phosphorylated peptides

por Kowalewska, Karolina, Stefanowicz, Piotr, Ruman, Tomasz, Frączyk, Tomasz, Rode, Wojciech, Szewczuk, Zbigniew
Publicado 2010