Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT

por Smith, Theresa M., Willardson, Barry M.
Publicado 2022

Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli

por Iacovelli, Riccardo, Sokolova, Nika, Haslinger, Kristina
Publicado 2022

Transcriptional plasticity of fibroblasts in heart disease

por Micheletti, Rudi, Alexanian, Michael
Publicado 2022

AMP-activated protein kinase — a journey from 1 to 100 downstream targets

por Hardie, D. Grahame
Publicado 2022

Strength in numbers: effect of protein crowding on the shape of cell membranes

por Ruhoff, Victoria Thusgaard, Moreno-Pescador, Guillermo, Pezeshkian, Weria, Bendix, Poul Martin
Publicado 2022

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors

por Steens, Jurre A., Salazar, Carl Raymund P., Staals, Raymond H.J.
Publicado 2022

Fundamental roles for inter-organelle communication in aging

por Donahue, Eric K. F., Ruark, Elizabeth M., Burkewitz, Kristopher
Publicado 2022

Propagation of Parkinson's disease by extracellular vesicle production and secretion

por Shippey, Laura E., Campbell, Susan G., Hill, Andrew F., Smith, David P.
Publicado 2022

Studying actin-induced cell shape changes using Giant Unilamellar Vesicles and reconstituted actin networks

por Lopes dos Santos, Rogério, Campillo, Clément
Publicado 2022

Dynamics of phagocytosis mediated by phosphatidylserine

por Vorselen, Daan
Publicado 2022

Mechanisms of TNF-independent RIPK3-mediated cell death

por Tummers, Bart, Green, Douglas R.
Publicado 2022

Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential

por Madgwick, Suzanne, Luli, Saimir, Sellier, Helene, Butterworth, Jacqueline A., Leslie, Jack, Moore, Adam J., Corbin, Emma K., Yemm, Adrian I., Chiremba, Robson T., Tiniakos, Dina, Oakley, Fiona, Perkins, Neil D., Hunter, Jill E.
Publicado 2022

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

por Hunter, Jill E., Campbell, Amy E., Butterworth, Jacqueline A., Sellier, Helene, Hannaway, Nicola L., Luli, Saimir, Floudas, Achilleas, Kenneth, Niall S., Moore, Adam J., Brownridge, Philip J., Thomas, Huw D., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Knight, Andrew M., Garrett, Michelle D., Collins, Ian, Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

por Hunter, Jill E., Campbell, Amy E., Kerridge, Scott, Fraser, Callum, Hannaway, Nicola L., Luli, Saimir, Ivanova, Iglika, Brownridge, Philip J., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S. R., Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

por Hunter, Jill E., Campbell, Amy E., Hannaway, Nicola L., Kerridge, Scott, Luli, Saimir, Butterworth, Jacqueline A., Sellier, Helene, Mukherjee, Reshmi, Dhillon, Nikita, Sudhindar, Praveen D., Shukla, Ruchi, Brownridge, Philip J., Bell, Hayden L., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Collins, Ian, Garrett, Michelle D., Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Analysis of DNMT1 gene variants in progression of neural tube defects—an in silico to in vitro approach

por Sadhukhan, Susanta, Paul, Nirvika, Ghosh, Sudakshina, Munian, Dinesh, Ganguly, Kausik, Ghosh, Krishnendu, Sengupta, Mainak, Das, Madhusudan
Publicado 2022

IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway

por Phair, Iain R., Sumoreeah, Megan C., Scott, Niamh, Spinelli, Laura, Arthur, J. Simon C.
Publicado 2022

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery

por May, Lauren T., Bartolo, Belinda A., Harrison, David G., Guzik, Tomasz, Drummond, Grant R., Figtree, Gemma A., Ritchie, Rebecca H., Rye, Kerry-Anne, de Haan, Judy B.
Publicado 2022

Retraction: 17β-estradiol binding to ERα promotes the progression of prolactinoma through estrogen-response element-induced CaBP-9k upregulation

Publicado 2022

Correction: Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes

Publicado 2022